{"product_id":"multidimensional-liquid-chromatography-theory-and-applications-in-industrial-chemistry-and-the-life-sciences-hardback-9780471738473","title":"Multidimensional Liquid Chromatography; Theory and Applications in Industrial Chemistry and the Life Sciences (Hardback) 9780471738473","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eMultidimensional Liquid Chromatography\u003c\/font\u003e\u003cbr\u003e\r\n\u003cfont size=\"5\"\u003eTheory and Applications in Industrial Chemistry and the Life Sciences\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eSteven A. Cohen (Edited by), SA Cohen (Author), Mark R. Schure (Edited by)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780471738473, Wiley\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 22 April 2008\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e480 pages\u003cbr\u003e24.4 x 16.3 x 2.9 cm, 0.83 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cem\u003e\u003cfont size=\"3\"\u003e\"It is a timely publication and present a valuable resource of scientific information on MDLC…It presents systematically gathered scientific information from a plethora of articles scattered over a wide range of sources. This effort should be appreciated by a wide audience of scientists and researchers who deal with complex separation programs in biomedical, environmental, and natural products; industrial polymers; food and other sources.\" (\u003ci\u003eJournal of the American Chemical Society\u003c\/i\u003e, November 12, 2008)\u003c\/font\u003e\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003eMultidimensional Liquid Chromatography (MDLC) is a very powerful separation technique for analyzing exceptionally complex samples in one step. This authoritative reference presents a number of recent contributions that help define the current art and science of MDLC. Topics covered include instrumentation, theory, methods development, and applications of MDLC in the life sciences and in industrial chemistry. With the information to help you perform very difficult separations of complex samples, this reference includes chapters contributed by leading experts or teams of experts.\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e\u003cp\u003eForeword xiii\u003c\/p\u003e \u003cp\u003ePreface xv\u003c\/p\u003e \u003cp\u003eContributors xvii\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 Introduction 1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1.1 Previous Literature Which Covers MDLC 4\u003c\/p\u003e \u003cp\u003e1.2 How this Book is Organized 5\u003c\/p\u003e \u003cp\u003eReferences 6\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart I Theory 9\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 Elements of the Theory of Multidimensional Liquid Chromatography 11\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e2.1 Introduction 11\u003c\/p\u003e \u003cp\u003e2.2 Peak Capacity 13\u003c\/p\u003e \u003cp\u003e2.3 Resolution 17\u003c\/p\u003e \u003cp\u003e2.4 Orthogonality 19\u003c\/p\u003e \u003cp\u003e2.5 Two-Dimensional Theory of Peak Overlap 21\u003c\/p\u003e \u003cp\u003e2.6 Dimensionality, Peak Ordering, and Clustering 23\u003c\/p\u003e \u003cp\u003e2.7 Theory of Zone Sampling 24\u003c\/p\u003e \u003cp\u003e2.8 Dilution and Limit of Detection 26\u003c\/p\u003e \u003cp\u003e2.9 Chemometric Analysis 27\u003c\/p\u003e \u003cp\u003e2.10 Future Directions 28\u003c\/p\u003e \u003cp\u003eReferences 30\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Peak Capacity in Two-Dimensional Liquid Chromatography 35\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e3.1 Introduction 35\u003c\/p\u003e \u003cp\u003e3.2 Theory 37\u003c\/p\u003e \u003cp\u003e3.3 Procedures 41\u003c\/p\u003e \u003cp\u003e3.4 Results and Discussion 42\u003c\/p\u003e \u003cp\u003e3.5 Conclusions 49\u003c\/p\u003e \u003cp\u003eAppendix 3A Generation of Random Correlated Coordinates 50\u003c\/p\u003e \u003cp\u003eAppendix 3B Derivation of Limiting Correlation Coefficient r 54\u003c\/p\u003e \u003cp\u003eReferences 56\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Decoding Complex 2D Separations 59\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e4.1 Introduction 59\u003c\/p\u003e \u003cp\u003e4.2 Fundamentals: The Statistical Description of Complex Multicomponent Separations 62\u003c\/p\u003e \u003cp\u003e4.3 Decoding 1D and 2D Multicomponent Separations by Using the SMO Poisson Statistics 68\u003c\/p\u003e \u003cp\u003e4.4 Decoding Multicomponent Separations by the Autocovariance Function 74\u003c\/p\u003e \u003cp\u003e4.5 Application to 2D Separations 78\u003c\/p\u003e \u003cp\u003e4.5.1 Results from SMO Method 81\u003c\/p\u003e \u003cp\u003e4.5.2 Results from 2D Autocovariance Function Method 84\u003c\/p\u003e \u003cp\u003e4.6 Concluding Remarks 88\u003c\/p\u003e \u003cp\u003eAcknowledgments 88\u003c\/p\u003e \u003cp\u003eReferences 88\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart II Columns, Instrumentation and Methods Development 91\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Instrumentation for Comprehensive Multidimensional Liquid Chromatography 93\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e5.1 Introduction 93\u003c\/p\u003e \u003cp\u003e5.2 Heart-Cutting Versus Comprehensive Mode 95\u003c\/p\u003e \u003cp\u003e5.3 Chromatographic Hardware 97\u003c\/p\u003e \u003cp\u003e5.3.1 Valves 97\u003c\/p\u003e \u003cp\u003e5.4 CE Interfaces 104\u003c\/p\u003e \u003cp\u003e5.4.1 Gated Interface for HPLC–CE 104\u003c\/p\u003e \u003cp\u003e5.4.2 Microfluidic Valves for On-Chip Multidimensional Analysis 105\u003c\/p\u003e \u003cp\u003e5.5 Columns and Combinations 106\u003c\/p\u003e \u003cp\u003e5.5.1 Column Systems, Dilution, and Splitting 108\u003c\/p\u003e \u003cp\u003e5.6 Detection 109\u003c\/p\u003e \u003cp\u003e5.7 Computer Hardware and Software 109\u003c\/p\u003e \u003cp\u003e5.7.1 Software Development 110\u003c\/p\u003e \u003cp\u003e5.7.2 Valve Sequencing 111\u003c\/p\u003e \u003cp\u003e5.7.3 Data Format and Storage 113\u003c\/p\u003e \u003cp\u003e5.8 Zone Visualization 115\u003c\/p\u003e \u003cp\u003e5.8.1 Contour Visualization 115\u003c\/p\u003e \u003cp\u003e5.8.2 2D Peak Presentation 117\u003c\/p\u003e \u003cp\u003e5.8.3 Zone Visualization in Specific Chemical (pI) Regions 117\u003c\/p\u003e \u003cp\u003e5.8.4 External Plotting Programs 117\u003c\/p\u003e \u003cp\u003e5.8.5 Difference Plots 118\u003c\/p\u003e \u003cp\u003e5.8.6 Multi-channel Data 118\u003c\/p\u003e \u003cp\u003e5.9 Data Analysis and Signal Processing 119\u003c\/p\u003e \u003cp\u003e5.10 Future Prospects 120\u003c\/p\u003e \u003cp\u003eReferences 121\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 Method Development in Comprehensive Multidimensional Liquid Chromatography 127\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e6.1 Introduction 127\u003c\/p\u003e \u003cp\u003e6.2 Previous Work 128\u003c\/p\u003e \u003cp\u003e6.3 Column Variables 130\u003c\/p\u003e \u003cp\u003e6.4 Method Development 130\u003c\/p\u003e \u003cp\u003e6.4.1 The Cardinal Rules of 2DLC Method Development 132\u003c\/p\u003e \u003cp\u003e6.5 Planning the Experiment 143\u003c\/p\u003e \u003cp\u003e6.6 General Comments on Optimizing the 2DLC Experiment: Speed–Resolution Trade-off 143\u003c\/p\u003e \u003cp\u003eAcknowledgment 144\u003c\/p\u003e \u003cp\u003eReferences 144\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 Monolithic Columns and Their 2D-HPLC Applications 147\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e7.1 Introduction 147\u003c\/p\u003e \u003cp\u003e7.2 Monolithic Polymer Columns 148\u003c\/p\u003e \u003cp\u003e7.2.1 Structural Properties of Polymer Monoliths 148\u003c\/p\u003e \u003cp\u003e7.2.2 Chromatographic Properties of Polymer Monolithic Columns 150\u003c\/p\u003e \u003cp\u003e7.2.3 Two-Dimensional HPLC Using Polymer Monoliths 152\u003c\/p\u003e \u003cp\u003e7.3 Monolithic Silica Columns 153\u003c\/p\u003e \u003cp\u003e7.3.1 Preparation 154\u003c\/p\u003e \u003cp\u003e7.3.2 Structural Properties of Monolithic Silica Columns 154\u003c\/p\u003e \u003cp\u003e7.3.3 Chromatographic Properties of Monolithic Silica Columns 156\u003c\/p\u003e \u003cp\u003e7.4 Peak Capacity Increase by Using Monolithic Silica Columns in Gradient Elution 158\u003c\/p\u003e \u003cp\u003e7.5 2D HPLC Using Monolithic Silica Columns 159\u003c\/p\u003e \u003cp\u003e7.5.1 RP-RP 2D HPLC Using Two Different Columns 161\u003c\/p\u003e \u003cp\u003e7.5.2 RP–RP 2D HPLC Using Two Similar Columns 164\u003c\/p\u003e \u003cp\u003e7.5.3 Ion Exchange–Reversed-Phase 2D HPLC Using a Monolithic Column for the 2nd-D 166\u003c\/p\u003e \u003cp\u003e7.5.4 IEX-RP 2D HPLC Using a Monolithic RP Capillary Column for the 2nd-D 168\u003c\/p\u003e \u003cp\u003e7.6 Summary and Future Improvement of 2D HPLC 171\u003c\/p\u003e \u003cp\u003eReferences 171\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 Ultrahigh Pressure Multidimensional Liquid Chromatography 177\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e8.1 Background: MDLC in the Jorgenson Lab 177\u003c\/p\u003e \u003cp\u003e8.1.1 Cation Exchange–Size Exclusion 178\u003c\/p\u003e \u003cp\u003e8.1.2 Anion Exchange–Reversed Phase 180\u003c\/p\u003e \u003cp\u003e8.1.3 Cation Exchange–Reversed Phase 181\u003c\/p\u003e \u003cp\u003e8.1.4 Size Exclusion–Reversed Phase 183\u003c\/p\u003e \u003cp\u003e8.2 Online Versus Off-Line MDLC 188\u003c\/p\u003e \u003cp\u003e8.3 MDLC Using Ultrahigh Pressure Liquid Chromatography: Benefits and Challenges 189\u003c\/p\u003e \u003cp\u003e8.3.1 An Introduction to UHPLC 190\u003c\/p\u003e \u003cp\u003e8.3.2 UHPLC for LC LC: High Speed Versus High Peak Capacity 191\u003c\/p\u003e \u003cp\u003e8.3.3 LC UHPLC for Separations of Intact Proteins 191\u003c\/p\u003e \u003cp\u003e8.4 Experimental Details 193\u003c\/p\u003e \u003cp\u003e8.4.1 Instrumentation 193\u003c\/p\u003e \u003cp\u003e8.4.2 Data Analysis 194\u003c\/p\u003e \u003cp\u003e8.4.3 Chromatographic Conditions 195\u003c\/p\u003e \u003cp\u003e8.4.4 Samples 196\u003c\/p\u003e \u003cp\u003e8.5 Results and Discussion 196\u003c\/p\u003e \u003cp\u003e8.6 Future Directions for UHP-MDLC 202\u003c\/p\u003e \u003cp\u003eReferences 203\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart III Life Science Applications 205\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 Peptidomics 207\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e9.1 State of the Art—Why Peptidomics? 207\u003c\/p\u003e \u003cp\u003e9.2 Strategies and Solutions 208\u003c\/p\u003e \u003cp\u003e9.3 Summary and Conclusions 218\u003c\/p\u003e \u003cp\u003eReferences 218\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 A Two-Dimensional Liquid Mass Mapping Technique for Biomarker Discovery 221\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e10.1 Introduction 221\u003c\/p\u003e \u003cp\u003e10.2 Methods for Separating and Identifying Proteins 223\u003c\/p\u003e \u003cp\u003e10.2.1 pI-Based Methods of Separation 223\u003c\/p\u003e \u003cp\u003e10.2.2 Chromatofocusing-A Column Based pH Separation 225\u003c\/p\u003e \u003cp\u003e10.2.3 Nonporous Separation of Proteins 226\u003c\/p\u003e \u003cp\u003e10.2.4 Electrospray-Time of Flight-Mass Spectrometry 228\u003c\/p\u003e \u003cp\u003e10.2.5 MALDI Peptide Mass Fingerprinting 229\u003c\/p\u003e \u003cp\u003e10.2.6 Data Analysis and Recombination 230\u003c\/p\u003e \u003cp\u003e10.3 Applications 230\u003c\/p\u003e \u003cp\u003e10.3.1 Proteomic Mapping and Clustering of Multiple Samples—Application to Ovarian Cancer Cell Lines 230\u003c\/p\u003e \u003cp\u003e10.3.2 2D Liquid Mass Mapping of Tumor Cell Line Secreted Samples, Application to Metastasis-Associated Protein Profiles 233\u003c\/p\u003e \u003cp\u003e10.3.3 Identification Annotation and Data Correlation in MCF10 Human Breast Cancer Cell Lines 235\u003c\/p\u003e \u003cp\u003e10.4 Summary and Conclusions 237\u003c\/p\u003e \u003cp\u003eAcknowledgments 238\u003c\/p\u003e \u003cp\u003eReferences 238\u003c\/p\u003e \u003cp\u003e\u003cb\u003e11 Coupled Multidimensional Chromatography and Tandem Mass Spectrometry Systems for Complex Peptide Mixture Analysis 243\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e11.1 Scx-rp\/ms\/ms 245\u003c\/p\u003e \u003cp\u003e11.2 Scx\/rp\/ms\/ms 248\u003c\/p\u003e \u003cp\u003e11.3 MudPIT 251\u003c\/p\u003e \u003cp\u003e11.4 Alternative First Dimension Approaches 254\u003c\/p\u003e \u003cp\u003e11.5 Conclusion 255\u003c\/p\u003e \u003cp\u003eReferences 255\u003c\/p\u003e \u003cp\u003e\u003cb\u003e12 Development of Orthogonal 2DLC Methods for Separation of Peptides 261\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e12.1 Introduction 261\u003c\/p\u003e \u003cp\u003e12.2 Previous Work 263\u003c\/p\u003e \u003cp\u003e12.3 Developing Orthogonal 2DLC Methods 264\u003c\/p\u003e \u003cp\u003e12.3.1 LC Selectivity for Peptides: Experimental Design 264\u003c\/p\u003e \u003cp\u003e12.3.2 Investigation of 2DLC Orthogonality for Separation of Peptides 266\u003c\/p\u003e \u003cp\u003e12.3.3 Geometric Approach to Orthogonality in 2DLC 271\u003c\/p\u003e \u003cp\u003e12.3.4 Practical 2DLC Considerations in Proteome Research 275\u003c\/p\u003e \u003cp\u003e12.3.5 Evaluation of Selected 2DLC MS\/MS Systems 276\u003c\/p\u003e \u003cp\u003e12.3.6 Peak Capacity in 2DLC-MS\/MS 280\u003c\/p\u003e \u003cp\u003e12.3.7 Considerations of Concentration Dynamic Range 282\u003c\/p\u003e \u003cp\u003e12.4 Conclusions 284\u003c\/p\u003e \u003cp\u003eAcknowledgment 284\u003c\/p\u003e \u003cp\u003eReferences 284\u003c\/p\u003e \u003cp\u003e\u003cb\u003e13 Multidimensional Separation of Proteins with Online Electrospray Time-of-Flight Mass Spectrometric Detection 291\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e13.1 Introduction 291\u003c\/p\u003e \u003cp\u003e13.2 Chromatographic Parameters 293\u003c\/p\u003e \u003cp\u003e13.3 Analyte Detection and Subsequent Analysis 293\u003c\/p\u003e \u003cp\u003e13.4 Building a Multidimensional Protein Separation 294\u003c\/p\u003e \u003cp\u003e13.4.1 Selection of an Ion-Exchange–Reversed-Phase Separation System for Protein-Level Separations 295\u003c\/p\u003e \u003cp\u003e13.4.2 Chromatographic Sorbent Considerations 295\u003c\/p\u003e \u003cp\u003e13.4.3 Chromatographic Behavior of Proteins 296\u003c\/p\u003e \u003cp\u003e13.5 Comprehensive Multidimensional Chromatographic Systems 296\u003c\/p\u003e \u003cp\u003e13.6 Coupling 2DLC with Online ESI–MS Detection 299\u003c\/p\u003e \u003cp\u003e13.6.1 Interactions between the Two Dimensions of Chromatography (Step Vs. Linear) 304\u003c\/p\u003e \u003cp\u003e13.6.2 Recognizing Increased Selectivity in 2DLC Separations 306\u003c\/p\u003e \u003cp\u003e13.7 Expanding Multidimensional Separations into a “Middle-Out” Approach to Proteomic Analysis 308\u003c\/p\u003e \u003cp\u003e13.8 Future Directions in Protein MDLC 311\u003c\/p\u003e \u003cp\u003e13.8.1 Protein Chromatography 312\u003c\/p\u003e \u003cp\u003e13.8.2 MS Analysis of Proteins 313\u003c\/p\u003e \u003cp\u003e13.8.3 Data Interpretation 314\u003c\/p\u003e \u003cp\u003e13.9 Conclusion 314\u003c\/p\u003e \u003cp\u003eReferences 315\u003c\/p\u003e \u003cp\u003e\u003cb\u003e14 Analysis of Enantiomeric Compounds Using Multidimensional Liquid Chromatography 319\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e14.1 Online Achiral-Chiral LC-LC 320\u003c\/p\u003e \u003cp\u003e14.2 Applications 323\u003c\/p\u003e \u003cp\u003e14.2.1 Analysis of Enantiomers in Plasma and Urine 323\u003c\/p\u003e \u003cp\u003e14.3 Amino Acids 328\u003c\/p\u003e \u003cp\u003e14.3.1 Physiological Fluids or Tissues 328\u003c\/p\u003e \u003cp\u003e14.3.2 In Food, Beverages, and Other Products 333\u003c\/p\u003e \u003cp\u003e14.4 Other Applications 334\u003c\/p\u003e \u003cp\u003e14.4.1 Analysis of Enantiomers from Plant and Environmental Sources 334\u003c\/p\u003e \u003cp\u003e14.5 Miscellaneous Applications 336\u003c\/p\u003e \u003cp\u003e14.6 Conclusion 338\u003c\/p\u003e \u003cp\u003eReferences 339\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart IV Multidimensional Separation Using Capillary Electrophoresis 345\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e15 Two-Dimensional Capillary Electrophoresis for the Comprehensive Analysis of Complex Protein Mixtures 347\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e15.1 Introduction 347\u003c\/p\u003e \u003cp\u003e15.2 Previous Work 348\u003c\/p\u003e \u003cp\u003e15.2.1 Miniaturized IEF\/SDS-PAGE 348\u003c\/p\u003e \u003cp\u003e15.2.2 One-Dimensional Capillary Electrophoresis for Protein Analysis 349\u003c\/p\u003e \u003cp\u003e15.3 Two-Dimensional Capillary Separations for Analysis of Peptides and Proteins 352\u003c\/p\u003e \u003cp\u003e15.3.1 Capillary Liquid Chromatography Coupled with Capillary Electrophoresis for Analysis of Unlabeled Peptides and Proteins 352\u003c\/p\u003e \u003cp\u003e15.3.2 Two-Dimensional Capillary Electrophoresis for Analysis of Proteins 352\u003c\/p\u003e \u003cp\u003e15.3.3 High-Speed Two-Dimensional Capillary Electrophoresis 356\u003c\/p\u003e \u003cp\u003e15.3.4 The Analysis of a Single Fixed Cell 358\u003c\/p\u003e \u003cp\u003e15.4 Conclusions 360\u003c\/p\u003e \u003cp\u003e15.5 Abbreviations 360\u003c\/p\u003e \u003cp\u003eReferences 360\u003c\/p\u003e \u003cp\u003e\u003cb\u003e16 Two-Dimensional HPLC–CE Methods for Protein\/Peptide Separation 365\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e16.1 Introduction 365\u003c\/p\u003e \u003cp\u003e16.2 Off-line Versus Online 366\u003c\/p\u003e \u003cp\u003e16.3 HPLC Fractionation 366\u003c\/p\u003e \u003cp\u003e16.4 2d Hplc–ce 367\u003c\/p\u003e \u003cp\u003e16.5 CE–MS Detection 368\u003c\/p\u003e \u003cp\u003e16.6 Applications 370\u003c\/p\u003e \u003cp\u003e16.7 Concluding Remarks 380\u003c\/p\u003e \u003cp\u003eAcknowledgment 381\u003c\/p\u003e \u003cp\u003eReferences 381\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart V Industrial Applications 385\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e17 Multidimensional Liquid Chromatography in Industrial Applications 387\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e17.1 Introduction 387\u003c\/p\u003e \u003cp\u003e17.2 Principles of Multidimensional Liquid Chromatography as Applied to Polymer Analysis 390\u003c\/p\u003e \u003cp\u003e17.3 Experimental 393\u003c\/p\u003e \u003cp\u003e17.4 Analysis of Alkylene Oxide-Based Polymers 395\u003c\/p\u003e \u003cp\u003e17.4.1 Amphiphilic Polyalkylene Oxides 395\u003c\/p\u003e \u003cp\u003e17.5 Excipients 399\u003c\/p\u003e \u003cp\u003e17.6 Polyether Polyols 403\u003c\/p\u003e \u003cp\u003e17.7 Analysis of Condensation Polymers 406\u003c\/p\u003e \u003cp\u003e17.8 Polyamides 407\u003c\/p\u003e \u003cp\u003e17.9 Aromatic Polyesters 414\u003c\/p\u003e \u003cp\u003e17.10 Aliphatic Polyesters 417\u003c\/p\u003e \u003cp\u003eReferences 420\u003c\/p\u003e \u003cp\u003e\u003cb\u003e18 The Analysis of Surfactants by Multidimensional Liquid Chromatography 425\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e18.1 Introduction 425\u003c\/p\u003e \u003cp\u003e18.2 Analytical Characterization Methods 428\u003c\/p\u003e \u003cp\u003e18.2.1 CE and CGE 429\u003c\/p\u003e \u003cp\u003e18.2.2 Sec 430\u003c\/p\u003e \u003cp\u003e18.2.3 Nplc 431\u003c\/p\u003e \u003cp\u003e18.2.4 Rplc 433\u003c\/p\u003e \u003cp\u003e18.3 Detection Methods 434\u003c\/p\u003e \u003cp\u003e18.4 2dlc 434\u003c\/p\u003e \u003cp\u003e18.4.1 RPLC Coupled to SEC 435\u003c\/p\u003e \u003cp\u003e18.4.2 NPLC Coupled to RPLC 435\u003c\/p\u003e \u003cp\u003e18.5 Conclusions 442\u003c\/p\u003e \u003cp\u003eReferences 443\u003c\/p\u003e \u003cp\u003eIndex 447\u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Chemistry [\u003ca title=\"See our other books on Chemistry\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Chemistry%20%5BPN%5D%22\"\u003ePN\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Wiley-Interscience","offers":[{"title":"Brand New","offer_id":52298047127832,"sku":"9780471738473","price":130.86,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/files\/9780471738473.jpg?v=1781732538","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/multidimensional-liquid-chromatography-theory-and-applications-in-industrial-chemistry-and-the-life-sciences-hardback-9780471738473","provider":"Freshly Printed Books","version":"1.0","type":"link"}