{"product_id":"metabolomics-by-in-vivo-nmr-hardback-9780470847190","title":"Metabolomics by In Vivo NMR (Hardback) 9780470847190","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eMetabolomics by In Vivo NMR\u003c\/font\u003e\u003cbr\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003c\/p\u003e\n\u003cp\u003e\u003cfont size=\"4\"\u003eRobert G. Shulman (Edited by), RG Shulman (Author), Douglas L. Rothman (Edited by)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780470847190, Wiley\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 17 December 2004\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e208 pages\u003cbr\u003e25.1 x 19.4 x 1.7 cm, 0.595 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003e\u003ci\u003eMetabolism By In Vivo NMR\u003c\/i\u003e reviews and extends the experimental and theoretical reports concerning in vivo NMR, a pioneering approach that offers versatile new ways of studying metabolic pathways. Perfectly timed to coincide with recent findings that demonstrate the novelty and strength of this approach, the book covers recent applications in biochemistry, medicine, and psychology; in vivo NMR techniques; MCA; glucose metabolism focusing on glycogen; the value of muscle glycogen measurements in exercise; and much more. \u003cul\u003e \u003cli\u003eThis book is unique in linking in vivo 13C NMR measurements of neuronal activity and energetics with applications to functional imaging and certain disease states\u003c\/li\u003e \u003cli\u003eProvides a fundamental neurochemical explanation of brain activity applicable to functional imaging, theories of neuronal activity and disease states, e.g. epilepsy, psychiatric diseases and developmental disorders\u003c\/li\u003e \u003cli\u003eNovel and potentially controversial\u003c\/li\u003e \u003cli\u003eWill inspire future research directions.\u003c\/li\u003e \u003c\/ul\u003e\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e\u003cp\u003eContributors xi\u003c\/p\u003e \u003cp\u003eForeword xiii\u003cbr\u003e\u003ci\u003eSir George K. Radda, Medical Research Council, UK\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection A: Background\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1 Introduction 1\u003cbr\u003e\u003ci\u003eRobert G. Shulman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2 In Vivo NMR Spectroscopy – Techniques; Direct Detection; MRS; Kinetics and Labels; Fluxes; Concentrations 7\u003cbr\u003e\u003ci\u003eRobin de Graaf\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3 Metabolic Control Analysis for the NMR Spectroscopist 31\u003cbr\u003e\u003ci\u003eDavid A. Fell\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection B: 13C and 31P NMR Studies of the Regulation of Glucose Metabolism\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e4 MRS Studies of the Role of the Muscle Glycogen Synthesis Pathway in the Pathophysiology of Type 2 Diabetes 45\u003cbr\u003e\u003ci\u003eGerald I. Shulman and Douglas L. Rothman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5 Phosphorylation of Allosteric Enzymes can serve Homeostasis rather than Control Flux: the Example of Glycogen Synthase 59\u003cbr\u003e\u003ci\u003eJames R.A. Schafer, David A. Fell, Douglas Rothman and Robert G. Shulman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6 Regulation of Glycogen Metabolism in Muscle during Exercise 73\u003cbr\u003e\u003ci\u003eThomas B. Price\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7 13C NMR Studies of Heart Glycogen Metabolism 87\u003cbr\u003e\u003ci\u003eMaren R. Laughlin, Douglas L. Rothman and Robert G. Shulman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8 Bioenergetics Implication of Metabolic Fluctuation during Muscle Contraction 103\u003cbr\u003e\u003ci\u003eThomas Jue\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9 Lactate, Glycogen and Fatigue 125\u003cbr\u003e\u003ci\u003eRobert G. Shulman and Douglas L. Rothman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10 Futile Cycling in Yeast: How to Control Gluttony in the Midst of Plenty 137\u003cbr\u003e\u003ci\u003eJan den Hollander and Robert G. Shulman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e11 Trehalose Energetics in Yeast Spores 149\u003cbr\u003e\u003ci\u003eRobert G. Shulman and Jan den Hollander\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e12 Metabolic Networks in the Liver by 2H and 13C NMR 159\u003cbr\u003e\u003ci\u003eA. Dean Sherry and Craig R. Malloy\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e13 Summarized Reflections on Metabolism 175\u003cbr\u003e\u003ci\u003eRobert G. Shulman and James R. A. Schafer\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIndex 185\u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Chemistry [\u003ca title=\"See our other books on Chemistry\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Chemistry%20%5BPN%5D%22\"\u003ePN\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Wiley","offers":[{"title":"Brand New","offer_id":52278036168984,"sku":"9780470847190","price":148.65,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/files\/9780470847190.jpg?v=1781457069","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/metabolomics-by-in-vivo-nmr-hardback-9780470847190","provider":"Freshly Printed Books","version":"1.0","type":"link"}