{"product_id":"medicinal-chemistry-of-anticancer-drugs-paperback-9780444626493","title":"Medicinal Chemistry of Anticancer Drugs (Paperback \/ softback) 9780444626493","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eMedicinal Chemistry of Anticancer Drugs\u003c\/font\u003e\u003cbr\u003e\r\n\r\n\r\n\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eA concise, intermediate level book which bridges the gap between elementary sources and primary literature\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eCarmen Avendaño (Author), J. Carlos Menéndez (Author)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780444626493, Elsevier Science\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003ePaperback \/ softback, published 6 July 2015\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e768 pages, 40 illustrations (40 in full color)\u003cbr\u003e23.4 x 19 x 4.6 cm, 1.51 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cem\u003e\u003cfont size=\"3\"\u003e\"Through a mechanistic approach, this valuable guide provides the reader with the principles of modern drug design methods and their application in the cancer field.\" \u003cb\u003e--Anticancer Research\u003c\/b\u003e\u003c\/font\u003e\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003e\u003cp\u003e\u003ci\u003eMedicinal Chemistry of Anticancer Drugs, Second Edition, \u003c\/i\u003eprovides an updated treatment from the point of view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. \u003c\/p\u003e  \u003cp\u003eAntitumor chemotherapy is a very active field of research, and a huge amount of information on the topic is generated every year. Cytotoxic chemotherapy is gradually being supplemented by a new generation of drugs that recognize specific targets on the surface or inside cancer cells, and resistance to antitumor drugs continues to be investigated. While these therapies are in their infancy, they hold promise of more effective therapies with fewer side effects. \u003c\/p\u003e  \u003cp\u003eAlthough many books are available that deal with clinical aspects of cancer chemotherapy, this book provides a sorely needed update from the point of view of medicinal chemistry and drug design.\u003c\/p\u003e\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e1. Introduction to anticancer chemotherapy \u003cbr\u003e2. Antimetabolites \u003cbr\u003e3. Anticancer drugs that inhibit hormone action \u003cbr\u003e4. Anticancer drugs acting via radical species. Photosensitizers and photodynamic therapy of cancer. \u003cbr\u003e5. DNA alkylating agents \u003cbr\u003e6. Alkylating and non-alkylating compounds interacting with the DNA minor groove. \u003cbr\u003e7. DNA intercalation and inhibition of topoisomerases \u003cbr\u003e8. Anticancer drugs targeting tubulin and microtubules\u003cbr\u003e9. Drugs targeting signaling pathways for tumour cell growth and proliferation \u003cbr\u003e10.Other approaches to targeted therapy \u003cbr\u003e11.Drug targeting in anticancer chemotherapy\u003cbr\u003e12.Resistance to antitumour agents and drugs that modulate it\u003cbr\u003e13.Cancer chemoprevention\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Biochemistry [\u003ca title=\"See our other books on Biochemistry\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Biochemistry%20%5BPSB%5D%22\"\u003ePSB\u003c\/a\u003e], Organic chemistry [\u003ca title=\"See our other books on Organic chemistry\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Organic%20chemistry%20%5BPNN%5D%22\"\u003ePNN\u003c\/a\u003e], Pharmacology [\u003ca title=\"See our other books on Pharmacology\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Pharmacology%20%5BMMG%5D%22\"\u003eMMG\u003c\/a\u003e], Pharmaceutical industries [\u003ca title=\"See our other books on Pharmaceutical industries\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Pharmaceutical%20industries%20%5BKNDP%5D%22\"\u003eKNDP\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Elsevier Science","offers":[{"title":"Default Title","offer_id":46648882561304,"sku":"9780444626493","price":110.69,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/products\/9780444626493_b3a016bd-74d3-4afa-8953-ec22ade09cf1.jpg?v=1694987277","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/medicinal-chemistry-of-anticancer-drugs-paperback-9780444626493","provider":"Freshly Printed Books","version":"1.0","type":"link"}