{"product_id":"measuring-immunity-basic-science-and-clinical-practice-hardback-9780124559004","title":"Measuring Immunity; Basic Science and Clinical Practice (Hardback) 9780124559004","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eMeasuring Immunity\u003c\/font\u003e\u003cbr\u003e\r\n\u003cfont size=\"5\"\u003eBasic Science and Clinical Practice\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cem\u003eDiscusses the immunology principles behind the methods, discuss how and when various tests and therapies should be used and how to interpret results\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eMichael T. Lotze (Edited by), Angus W. Thomson (Edited by)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780124559004, Elsevier Science\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 25 December 2004\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e736 pages\u003cbr\u003e21.9 x 27.6 x 3.8 cm, 2.44 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cem\u003e\u003cfont size=\"3\"\u003e\"This is a fine reference that describes both the basic science background and the clinical applications of available measures of immune function that are currently used by researchers and clinicians. It appears to fill a niche for which there is no competition.\" \u003cb\u003e--Marion C. Cohen, PhD, University of Medicine and Dentistry of New Jersey-NJMS for Doody's: 3 Star Review\u003c\/b\u003e\u003c\/font\u003e\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003eMost of the diseases of modern mankind involve either acute or chronic inflammation. \u003cb\u003eMeasuring Immunity\u003c\/b\u003e integrates the current information available on biomarkers and surrogate assays into a single handbook. It highlights the principles behind various applications, gives a brief summary on how they are conducted and provides detailed and critical analyses of murine models of immunity, clinical trials, and tests to predict utility and benefit. \u003cb\u003eMeasuring Immunity\u003c\/b\u003e is indispensable for scientists and clinicians interested in the clinical applications of modern immunobiology.\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eIntroduction \u003cbr\u003ePreface \u003cbr\u003e\u003cb\u003eFUNDAMENTALS OF THE IMMMUNE RESPONSE\u003c\/b\u003e\u003cbr\u003eMHC Class I \u003cbr\u003eMHC Class II \u003cbr\u003eCytokine receptor heterogeneity \u003cbr\u003eMeasuring cytokine polymorphisms:  functional variations and disease associations \u003cbr\u003eSignaling molecules affecting immune response \u003cbr\u003eToll like receptors in innate immunity \u003cbr\u003eDNA sequence-specific transcription factors \u003cbr\u003eGenetic factors diversity in NK and NKT cells \u003cbr\u003e\u003cb\u003eSEROLOGIC ASSAYS\u003c\/b\u003e \u003cbr\u003eHandling sera and obtaining fluid from different compartments practical  considerations\u003cbr\u003eAcute- phase proteins and inflammation: immunological and clinical implications, Complement in health and disease \u003cbr\u003eImmunoglobulin titers and immunoglobulin subtypes \u003cbr\u003eHuman antiglobulin responses \u003cbr\u003eMeasuring Rheumatoid Factors \u003cbr\u003eAutoantibodies  \u003cbr\u003eMeasuring antibody affinity using fluorescence \u003cbr\u003eSLE associated tests  \u003cbr\u003eMultiplexed serum assays \u003cbr\u003e\u003cb\u003eCELLULAR ENUMERATION AND PHENOTYPING\u003c\/b\u003e \u003cbr\u003eHandling and storage of cells and sera: practical considerations \u003cbr\u003ePhenotypic and functional measurements on circulating immune cells and their subsets\u003cbr\u003eNatural Killer cells \u003cbr\u003eTetramer Analysis  \u003cbr\u003ePeripheral blood naive and memory B cells  \u003cbr\u003eDendritic cells  \u003cbr\u003eMonocytes and macrophages  \u003cbr\u003eTumor cells  \u003cbr\u003eIntracellular cytokine assays\u003cbr\u003e\u003cb\u003eCELLULAR FUNCTION AND PHYSIOLOGY\u003c\/b\u003e \u003cbr\u003eCytolytic assays\t \u003cbr\u003eMixed leukocyte reactions \u003cbr\u003eAntigen\/mitogen-stimulated lymphocyte proliferation   \u003cbr\u003eMonitoring cell death \u003cbr\u003eCytokine enzyme linked immunosorbent spot (ELISPOT) assay  \u003cbr\u003eTesting natural killer cells \u003cbr\u003e\u003cb\u003ePROVOCATIVE ASSAYS \u003ci\u003ein vivo\u003c\/i\u003e\u003c\/b\u003e \u003cbr\u003eDelayed type hypersensitivity responses \u003cbr\u003eRebuck windows: granulocyte function \u003cbr\u003eThe vascular and coagulation systems\t \u003cbr\u003eSentinel node assays  \u003cbr\u003eImaging inflammation                                        \u003cbr\u003e\u003cb\u003eASSAYS IN ACUTE AND CHRONIC DISEASES\u003c\/b\u003e \u003cbr\u003eCancer–solid tumors  \u003cbr\u003eCancer–hematologic disorders  \u003cbr\u003eAutoimmunity–type 1 diabetes \u003cbr\u003eAutoimmunity–systemic lupus erythematosus   \u003cbr\u003eAutoimmunity–multiple sclerosis \u003cbr\u003eAutoimmunity–gastrointestinal  \u003cbr\u003eAutoimmunity–endocrine \u003cbr\u003eAutoimmunity–vasculitisTransplantation  \u003cbr\u003eViral responses–HIV 1 \u003cbr\u003eViral responses–Epstein- Barr virus \u003cbr\u003eViral responses–hepatitis\u003cbr\u003eDermatology  \u003cbr\u003eAtherosclerosis  \u003cbr\u003ePrimary immunodeficiencies  \u003cbr\u003eAsthma and allergy \u003cbr\u003e\u003cb\u003eNEW TECHNOLOGIES\u003c\/b\u003e \u003cbr\u003eCerum proteomic profiling and analysis\u003cbr\u003eImaging cytometry \u003cbr\u003eCancer biometrics \u003cbr\u003eGenomics and microarrays  \u003cbr\u003eImage informatics \u003cbr\u003eINDEX of manufacturers and suppliers, addresses, web site\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Immunology [\u003ca title=\"See our other books on Immunology\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Immunology%20%5BMJCM%5D%22\"\u003eMJCM\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Academic Press","offers":[{"title":"Default Title","offer_id":46649421922584,"sku":"9780124559004","price":119.49,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/products\/9780124559004.jpg?v=1694100886","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/measuring-immunity-basic-science-and-clinical-practice-hardback-9780124559004","provider":"Freshly Printed Books","version":"1.0","type":"link"}