{"product_id":"machina-carnis-the-biochemistry-of-muscular-contraction-in-its-historical-development-paperback-9780521112673","title":"Machina Carnis; The Biochemistry of Muscular Contraction in its Historical Development (Paperback) 9780521112673","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eMachina Carnis\u003c\/font\u003e\u003cbr\u003e\r\n\u003cfont size=\"5\"\u003eThe Biochemistry of Muscular Contraction in its Historical Development\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cem\u003eThis book is an account of the centuries of experiment and speculation that have led to our understanding of how muscles work.\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eDorothy M. Needham (Author)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780521112673, Cambridge University Press\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003ePaperback, published 4 June 2009\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e820 pages\u003cbr\u003e22.9 x 15.2 x 4.1 cm, 1.9 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003eOriginally published in 1971, this is an account of the centuries of experiment and speculation that have led to our understanding of how muscles work. The book traces all the developments in the field since 1600 and devotes special attention to the breakthroughs made in the last century. It considers the nature of the muscle machine and its fuel, as well as the intricate regulation of energy supply under different conditions. It also examines the very varied kinds of muscle and the effects of some diseases on their structure and function. Finally it shows how the energy metabolism first elucidated for the mechanical work of muscle has been found to explain most of the other kinds of work done by cells, as in light production, secretion, ionic transport and electrical discharge. The biochemistry of muscle, carbohydrate metabolism and phosphorylations was the author's chosen field of research for over forty years.\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003ePreface\u003cbr\u003e 1. Bringing muscles into focus: the first two millennia\u003cbr\u003e 2. Muscle metabolism after the Chemical Revolution\u003cbr\u003e 3. the relationship between mechanical events, heat production and metabolism\u003cbr\u003e 4. The influence of brewing science on the study of muscle glycolysis\u003cbr\u003e 5. The discovery of phosphagen and adenosinetriphosphate\u003cbr\u003e 6. Adenosinetriphosphate as fuel and as phosphate-carrier\u003cbr\u003e 7. Early studies of msucle structure and theories of contraction\u003cbr\u003e 8. Interaction of actomyosin and ATP\u003cbr\u003e 9. Some theories of contraction mechanism\u003cbr\u003e 10. On myosin, actin and tropomyoson\u003cbr\u003e 11. The sliding mechanism\u003cbr\u003e 12. How does the sliding mechanism work?\u003cbr\u003e 13. Excitation, excitation-contraction coupling and relaxation\u003cbr\u003e 14. Happenings in intact muscle\u003cbr\u003e 15. Rigor and the chemical\u003cbr\u003e changes responsible for its onset\u003cbr\u003e 16. Respiration\u003cbr\u003e 17. Oxidative phosphorylation\u003cbr\u003e 18. The regulation of carbohydrate metabolism for energy supply to the muscle machine\u003cbr\u003e 19. A comparative study of the striated muscle of vertebrates\u003cbr\u003e 20. Enzymic and other effects of denervation, cross-innervation and repeated stimulation\u003cbr\u003e 21. some aspects of muscle disease\u003cbr\u003e 22. Contraction in muscles of invertebrates\u003cbr\u003e 23. Vertebrate smooth muscle\u003cbr\u003e 24. Energy provision and contactile proteins in non-muscular functions\u003cbr\u003e References.\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Biology, life sciences [\u003ca title=\"See our other books on Biology, life sciences\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Biology,%20life%20sciences%20%5BPS%5D%22\"\u003ePS\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Cambridge University Press","offers":[{"title":"Default Title","offer_id":46006492496152,"sku":"9780521112673","price":46.19,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/products\/9780521112673i_3e833b27-cd4a-48da-90e8-f566f3998eea.jpg?v=1691371261","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/machina-carnis-the-biochemistry-of-muscular-contraction-in-its-historical-development-paperback-9780521112673","provider":"Freshly Printed Books","version":"1.0","type":"link"}