{"product_id":"lahitas-systemic-lupus-erythematosus-hardback-9780128205839","title":"Lahita's Systemic Lupus Erythematosus (Hardback) 9780128205839","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eLahita's Systemic Lupus Erythematosus\u003c\/font\u003e\u003cbr\u003e\r\n\r\n\r\n\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eTranslational reference incorporating the most recent developments and advancement in the field, both in terms of clinical management and research\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eRobert G. Lahita (Edited by)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780128205839\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 27 July 2021\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e730 pages\u003cbr\u003e27.6 x 21.6 x 3.8 cm, 2.2 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003eApprox.698 pages\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e\u003cp\u003e\u003cb\u003ePart I: Basis of the Disease\u003c\/b\u003e \u003cb\u003eSection A: Genetics and epigenetics \u003c\/b\u003e1. Major histocompatibility complex and SLE 2. Lupus Susceptibility genes 3. Epigenetics in systemic lupus erythematosus and the integration of molecular pathways\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection B: Immunopathogenesis\u003c\/b\u003e 4. Autoantigens, antigenic mimicry, and immune complexes 5. B-cell Biology, tolerance and autoantibodies 6. T-Cell Biology, tolerance and regulation 7. Polymorphonuclear cells 8. Metabolic and mitochondrial dysfunction in SLE 9. Immunopathogenesis: the role of mucosal and skin microbiota in SLE\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection C: Disease effectors and modifiers\u003c\/b\u003e 10. Complement and SLE 11. Interferons and cytokines in SLE pathogenesis and therapy 12. Innate immunity in SLE pathogenesis 13. Sex bias in SLE\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection D: Tissue injury—the Biology\u003c\/b\u003e 14. Mechanisms of tissue injury in lupus nephritis 15. The skin 16. The brain in SLE: mechanisms and detection of injury and therapeutic strategies 17. The role of infections in SLE pathogenesis 18. Tissue injurydthe biology: SLE-associated vascular disease and antiphospholipid syndrome\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart II: Clinical presentation of disease Section A: Clinical presentation\u003c\/b\u003e 19. Epidemiology of SLE and related diseases: incidence, prevalence, and mortality 20. The clinical presentation of systemic lupus erythematosus and laboratory diagnosis 21. Passively acquired lupus in the fetus and neonate 22. Systemic lupus erythematosus in children 23. Environmental and drug-induced lupus 24. Reproductive health 25. Monitoring disease activity 26. Overlap syndromes\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection B: Specific organ involvement and clinical presentation\u003c\/b\u003e 27. Nervous system 28. Skin 29. Kidney disease 30. Cardiovascular disease in lupus 31. Pulmonary manifestations of systemic lupus erythematosus 32. GI hepatic and nonhepatic diseases 33. Musculoskeletal system: articular disease, myositis, and bone metabolism 34. Clinical presentation of antiphospholipid syndrome 35. Hematology: cytopenias 36. Malignancy risk and screening\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSection C: Treatment of systemic llupus erythematosus\u003c\/b\u003e 37. Antimalarial drugs (and lupus) 38. Glucocorticoids 39. Immunosuppressive therapy in SLE 40. Pipeline therapies and future drug development 41. Challenges of systemic lupus clinical trials\u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Pharmacology [\u003ca title=\"See our other books on Pharmacology\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Pharmacology%20%5BMMG%5D%22\"\u003eMMG\u003c\/a\u003e], Immunology [\u003ca title=\"See our other books on Immunology\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Immunology%20%5BMJCM%5D%22\"\u003eMJCM\u003c\/a\u003e], Physiology [\u003ca title=\"See our other books on Physiology\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Physiology%20%5BMFG%5D%22\"\u003eMFG\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Freshly Printed Books","offers":[{"title":"Default Title","offer_id":46648843305240,"sku":"9780128205839","price":195.79,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/products\/9780128205839.jpg?v=1694094545","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/lahitas-systemic-lupus-erythematosus-hardback-9780128205839","provider":"Freshly Printed Books","version":"1.0","type":"link"}