{"product_id":"isotope-tracers-in-metabolic-research-principles-and-practice-of-kinetic-analysis-hardback-9780471462095","title":"Isotope Tracers in Metabolic Research; Principles and Practice of Kinetic Analysis (Hardback) 9780471462095","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eIsotope Tracers in Metabolic Research\u003c\/font\u003e\u003cbr\u003e\r\n\u003cfont size=\"5\"\u003ePrinciples and Practice of Kinetic Analysis\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eRobert R. Wolfe (Author), David L. Chinkes (Author)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780471462095, Wiley\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 9 November 2004\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e488 pages, Drawings: 198 B\u0026amp;W, 0 Color; Tables: 48 B\u0026amp;W, 0 Color\u003cbr\u003e26.7 x 18.5 x 3.2 cm, 1.061 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cem\u003e\u003cfont size=\"3\"\u003e\"...is supported by a wealth of illustrations, tables, and exemplary calculations that will aid in comprehension...[an] excellent and much needed textbook.\" (\u003ci\u003eThe Quarterly Review of Biology\u003c\/i\u003e, March 2007)  \u003cp\u003e\"...should be required for anyone who desires to know more about metabolic tracer kinetics.\" (\u003ci\u003eJournal of the American Society for Mass Spectrometry\u003c\/i\u003e, September 2005)\u003c\/p\u003e \u003cp\u003e\"...an effective integration of theory and practical implementation...It effectively serves as a teaching textbook as well as a research item.\" (\u003ci\u003eE-STREAMS\u003c\/i\u003e, August 2005)\u003c\/p\u003e\u003c\/font\u003e\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003eIn the past few years, the number of applications of tracers for in vivo biomedical studies has greatly increased. New analytical tools at the genetic and protein levels have spurred this growth, opening the door for a deeper understanding of metabolic events. This in turn promises to yield significant advances in the understanding and treatment of human disease.  \u003cp\u003eNow fully revised and expanded, \u003ci\u003eIsotope Tracers in Metabolic Research\u003c\/i\u003e, Second Edition is the established definitive text on stable and radioactive isotope tracers. In unique, multidisciplinary fashion, it presents comprehensive coverage of new methodological, mathematical, and theoretical approaches.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eThis new Second Edition includes:\u003c\/b\u003e\u003c\/p\u003e \u003cul\u003e \u003cli\u003eAll-new chapters on nuclear magnetic resonance, mass isotopomer analysis, and methods of protein metabolism analysis\u003c\/li\u003e \u003cli\u003eA completely updated categorized list of over 750 references\u003c\/li\u003e \u003cli\u003eMajor advances in the development of mass isotopomer and positional isotopomer techniques, noninvasive isotope techniques for studying metabolic pathways, hyphenated techniques, and new tracer techniques\u003c\/li\u003e \u003cli\u003eThe latest developments in quantification of DNA synthesis and mass spectrometry spurred by genome sequencing and proteomics\u003c\/li\u003e \u003cli\u003eNew coverage of mathematical modeling\u003c\/li\u003e \u003cli\u003eExpanded coverage of microdialysis probes, laboratory procedures, and regulatory issues related to human studies\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eIn this complete guide to performing tracer studies, the authors systematically cover tracer selection, modeling considerations, sample derivitization, mass spectrometry analysis, and data interpretation. Problems and discussion questions highlight key points in each chapter. Isotope \u003ci\u003eTracers in Metabolic Research\u003c\/i\u003e, Second Edition offers students and researchers a comprehensive, practical resource for utilizing the latest tracer methodologies.\u003c\/p\u003e\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003ePreface.  \u003cp\u003eChapter 1. Basic Characteristics of Isotopic Tracers.\u003c\/p\u003e \u003cp\u003eChapter 2. Calculating Specific Activity and Radiation Dosages.\u003c\/p\u003e \u003cp\u003eChapter 3. Calculation of Substance Kinetics: Single-Pool Model.\u003c\/p\u003e \u003cp\u003eChapter 4. Calculation of Substrate Kinetics: Multiple-Pool Model.\u003c\/p\u003e \u003cp\u003eChapter 5. Mass Spectrometry: Instrumentation.\u003c\/p\u003e \u003cp\u003eChapter 6. Determination of Isotopic Enrichment.\u003c\/p\u003e \u003cp\u003eChapter 7. Measurement of Substrate Oxidation.\u003c\/p\u003e \u003cp\u003eChapter 8. Measurement of Total Energy Expenditure Using the Doubly Labeled Water Method.\u003c\/p\u003e \u003cp\u003eChapter 9. Mass Isotopomer Distribution Analysis.\u003c\/p\u003e \u003cp\u003eChapter 10. Glucose Metabolism.\u003c\/p\u003e \u003cp\u003eChapter 11. Lipid Kinetics.\u003c\/p\u003e \u003cp\u003eChapter 12. Whole Body Protein Synthesis and Breakdown.\u003c\/p\u003e \u003cp\u003eChapter 13. Measurement of the Synthesis of Specific Proteins.\u003c\/p\u003e \u003cp\u003eChapter 14. Measurement of Regional or Tissue Protein Breakdown.\u003c\/p\u003e \u003cp\u003eChapter 15. Arterial-Venous Balance Technique to Measure Amino Acid Kinetics.\u003c\/p\u003e \u003cp\u003eChapter 16. Nuclear Magnetic Resonance.\u003c\/p\u003e \u003cp\u003eGlossary.\u003c\/p\u003e \u003cp\u003eAbbreviations.\u003c\/p\u003e \u003cp\u003eIndex.\u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Biology, life sciences [\u003ca title=\"See our other books on Biology, life sciences\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Biology,%20life%20sciences%20%5BPS%5D%22\"\u003ePS\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Wiley-Liss","offers":[{"title":"Brand New","offer_id":52502987571480,"sku":"9780471462095","price":235.29,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/files\/9780471462095.jpg?v=1786322588","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/isotope-tracers-in-metabolic-research-principles-and-practice-of-kinetic-analysis-hardback-9780471462095","provider":"Freshly Printed Books","version":"1.0","type":"link"}