{"product_id":"inflammatory-bowel-disease-crossroads-of-microbes-epithelium-and-immune-systems-hardback-9780470090466","title":"Inflammatory Bowel Disease; Crossroads of Microbes, Epithelium and Immune Systems (Hardback) 9780470090466","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eInflammatory Bowel Disease\u003c\/font\u003e\u003cbr\u003e\r\n\u003cfont size=\"5\"\u003eCrossroads of Microbes, Epithelium and Immune Systems\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eDerek J. Chadwick (Edited by), Novartis (Author), Jamie A. Goode (Edited by)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780470090466, Wiley\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 12 November 2004\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e240 pages\u003cbr\u003e23.6 x 16 x 1.7 cm, 0.508 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cem\u003e\u003cfont size=\"3\"\u003e\"This is a well written book that provides a succinct, easy to read summary of the current concepts in IBD. The discussions following each chapter are invaluable.\" (\u003ci\u003eDoody's Book Review Service\u003c\/i\u003e)\u003c\/font\u003e\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003eInflammatory bowel disease (IBD) comprises a group of idiopathic diseases of the intestine characterized by chronic inflammation of the bowel with periods of exacerbation and remission. Although the exact cause of IBD remains undetermined, the condition appears to be related to a combination of genetic and environmental factors resulting in an aberrant activation of the mucosal immune system. This book contains a series of interdisciplinary discussions between clinical and basic scientists focusing on key issues such as: \u0026lt;\u0026gt; \u003cul\u003e \u003cli\u003eEpithelial cell and molecular biology, including apoptosis, necrosis and cell survival\u003c\/li\u003e \u003cli\u003eThe role of bacterial milieu and mucosal bacteria in the IBD and of prebiotic and probiotic therapy\u003c\/li\u003e \u003cli\u003eThe progress towards the identification of susceptibility genes and phenotype-determining genes\u003c\/li\u003e \u003cli\u003eThe pharmacogenetics of IBD\u003c\/li\u003e \u003cli\u003eMucosal immunology and therapeutic strategies stemming therefrom\u003c\/li\u003e \u003c\/ul\u003e\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e\u003cp\u003eSymposium on Inflammatory bowel disease-crossroads of microbes, epithelium and immune systems, held at the Novartis Foundation, London, 25 - 27 November 2003\u003c\/p\u003e \u003cp\u003eEditors: Derek Chadwick (Organizer) and Jamie Goode\u003c\/p\u003e \u003cp\u003eThis symposium is based on a proposal made by Derek Jewell and Bill Roediger\u003c\/p\u003e \u003cp\u003eDerek Jewell Chair's introduction 1\u003c\/p\u003e \u003cp\u003e\u003cb\u003eJohn D. Rioux\u003c\/b\u003e Progress towards identifying inflammatory bowel disease susceptibility genes 3\u003cbr\u003e\u003ci\u003eDiscussion\u003c\/i\u003e 11\u003c\/p\u003e \u003cp\u003e\u003cb\u003eT. Ahmad\u003c\/b\u003e Phenotype-determining genes in inflammatory bowel disease 17\u003cbr\u003e\u003ci\u003eDiscussion\u003c\/i\u003e 29\u003c\/p\u003e \u003cp\u003e\u003cb\u003eDermot Kelleher, Richard Farrell\u003c\/b\u003e and\u003cb\u003e Ross McManus\u003c\/b\u003e Pharmacogenetics of inflammatory bowel disease 41\u003cbr\u003e\u003ci\u003eDiscussion\u003c\/i\u003e 53\u003c\/p\u003e \u003cp\u003e\u003cb\u003eG.T. Macfarlane, E. Furrie\u003c\/b\u003e and\u003cb\u003e S. Macfarlane\u003c\/b\u003e Bacterial milieu and mucosal bacteria in ulcerative colitis 57\u003cbr\u003e\u003ci\u003eDiscussion\u003c\/i\u003e 64\u003c\/p\u003e \u003cp\u003e\u003cb\u003eY. R. Mahida\u003c\/b\u003e and\u003cb\u003e R. N. Cunliffe\u003c\/b\u003e Defensins and mucosal protection 71\u003cbr\u003e\u003ci\u003eDiscussion\u003c\/i\u003e 77\u003c\/p\u003e \u003cp\u003e\u003cb\u003eW. E.W. Roediger\u003c\/b\u003e Intestinal mycoplasma in Crohn's disease 85\u003cbr\u003e\u003ci\u003eDiscussion\u003c\/i\u003e 93\u003c\/p\u003e \u003cp\u003e\u003cb\u003eJohn H. Cummings \u003c\/b\u003eand\u003cb\u003e San Choon Kong\u003c\/b\u003e Probiotics, prebiotics and antibiotics in inflammatory bowel disease 99\u003cbr\u003e\u003ci\u003eDiscussion\u003c\/i\u003e 112\u003c\/p\u003e \u003cp\u003e\u003cb\u003eAndrei I. Ivanov, Asma Nusrat\u003c\/b\u003e and\u003cb\u003e Charles A. Parkos\u003c\/b\u003e The epithelium in inflammatory bowel disease: potential role of endocytosis of junctional proteins in barrier disruption 115\u003cbr\u003e\u003ci\u003eDiscussion\u003c\/i\u003e 124\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePeter R. Gibson\u003c\/b\u003e Apoptosis or necrosis ö colonic epithelial cell survival 133\u003cbr\u003e\u003ci\u003eDiscussion\u003c\/i\u003e 145\u003c\/p\u003e \u003cp\u003e\u003cb\u003eKen Takeuchi, Laurence Maiden\u003c\/b\u003e and\u003cb\u003e Ingvar Bjarnason\u003c\/b\u003e Genetic aspects of intestinal permeability in inflammatory bowel disease 151\u003cbr\u003e\u003ci\u003eDiscussion\u003c\/i\u003e 159\u003c\/p\u003e \u003cp\u003e\u003cb\u003eFiona Powrie\u003c\/b\u003e and\u003cb\u003e Holm Uhlig\u003c\/b\u003e Animal models of intestinal inflammation: clues to the pathogenesis of inflammatory bowel disease 164\u003cbr\u003e\u003ci\u003eDiscussion\u003c\/i\u003e 174\u003c\/p\u003e \u003cp\u003e\u003cb\u003eHolm H. Uhlig, Christian Mottet\u003c\/b\u003e and\u003cb\u003e Fiona Powrie\u003c\/b\u003e Homing of intestinal immune cells 179\u003cbr\u003e\u003ci\u003eDiscussion\u003c\/i\u003e 188\u003c\/p\u003e \u003cp\u003e\u003cb\u003eS. Ghosh\u003c\/b\u003e Anti-TNF therapy in Crohn's disease 193\u003cbr\u003e\u003ci\u003eDiscussion\u003c\/i\u003e 205\u003c\/p\u003e \u003cp\u003eFinal discussion 211\u003cbr\u003eIndex of contributors 219\u003cbr\u003eSubject index 221\u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Biology, life sciences [\u003ca title=\"See our other books on Biology, life sciences\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Biology,%20life%20sciences%20%5BPS%5D%22\"\u003ePS\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Wiley","offers":[{"title":"Brand New","offer_id":52405524758808,"sku":"9780470090466","price":143.29,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/files\/9780470090466.jpg?v=1784136165","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/inflammatory-bowel-disease-crossroads-of-microbes-epithelium-and-immune-systems-hardback-9780470090466","provider":"Freshly Printed Books","version":"1.0","type":"link"}