{"product_id":"in-vitro-methods-in-toxicology-paperback-9780521104753","title":"In Vitro Methods in Toxicology (Paperback \/ softback) 9780521104753","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eIn Vitro Methods in Toxicology\u003c\/font\u003e\u003cbr\u003e\r\n\r\n\r\n\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eThe volume brings together the once disparate knowledge of cultural techniques and thus provides an important reference work for industrial and academic toxicologists.\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eC. K. Atterwill (Edited by), C. E. Steele (Edited by)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780521104753, Cambridge University Press\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003ePaperback \/ softback, published 19 March 2009\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e472 pages\u003cbr\u003e22.9 x 15.2 x 2.7 cm, 0.69 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003eFirst published in 1987, this book describes tissue (cell and organ) culture techniques which could be used at a critical predevelopment stage to screen for drug-inducing toxicity or to analyse the molecular mechanisms of toxicity at a later stage in parallel with investigative studies. This type of research has important ethical, financial and scientific implications. In particular, less animals and compound are required in in vitro research and more detailed information at the cellular and subcellular levels can be obtained. The volume brings together the once disparate knowledge of cultural techniques and thus provides an important reference work for industrial and academic toxicologists. It could also form a framework for discussion of potential improvements and modification of toxicity testing.\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eIntroduction G. B. Leslie and P. Johnson\u003cbr\u003e Part I. Target Organ Toxicity: 1. In vitro methods in renal toxicology M. A. Snith, W. R. Hewitt and J. Hook\u003cbr\u003e 2. Ototoxicity E. S. Harpur\u003cbr\u003e 3. Cultured cell models for studying problems in cardiac toxicology N. Sperelakis and G. Bkaily\u003cbr\u003e 4. Use of the isolated rat heart for the detection of cardiotoxic agents A. Cockburn\u003cbr\u003e 5. Brain reaggregate cultures in neurotoxicological investigations C. K. Atterwill\u003cbr\u003e 6. Application of thyroid cell culture to the study of thyrotoxicity C. G. Brown\u003cbr\u003e 7. In vitro methods to investigate toxic lung disease A. Poole and R. C. Brown\u003cbr\u003e 8. Metabolism and toxicity of drugs in mammalian hepatocyte culture R. J. Chenery\u003cbr\u003e 9. In vitro evaluation of haemic systems in toxicology J. S. H. Luke and G. R. Betton\u003cbr\u003e Part II. General and Topical Toxicity: 10. The chorioallantoic membrance in irritancy testing R. S. Lawrence\u003cbr\u003e 11. In vitro dermal irritancy tests P. A. Duffy and O. P. Flint\u003cbr\u003e 12. Genetic toxicology M. Richold\u003cbr\u003e 13. In vitro immunotoxicology K. Miller, S. Nicklin and S. G. Volsen\u003cbr\u003e Part III. Reproductive Toxicity: 14. An in vitro test for teratogens using cultures of rat embryo cells O. P. Flint\u003cbr\u003e 15. Postimplantion embryo culture and its application to problems in teratology D. L. Cockroft and C. E. Steele\u003cbr\u003e 16. Sub-mammalian and sub-vertebrate models in teratogenicity screening S. J. Freeman and N. A. Brown\u003cbr\u003e 17. The use of in vitro techniques to investigate the action of testicular toxicants D. A. Garside\u003cbr\u003e 18. An in vitro assessment of ovarian function: a potential tool for investigating mechanisms of toxicity in the ovary D. A. Garside and P. McKibbin\u003cbr\u003e Part IV. Conclusion: 19. Conclusion C. K. Atterwill and C. E. Steele\u003cbr\u003e Index.\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Pharmacology [\u003ca title=\"See our other books on Pharmacology\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Pharmacology%20%5BMMG%5D%22\"\u003eMMG\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Cambridge University Press","offers":[{"title":"Default Title","offer_id":46006411690264,"sku":"9780521104753","price":46.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/products\/9780521104753i.jpg?v=1694976003","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/in-vitro-methods-in-toxicology-paperback-9780521104753","provider":"Freshly Printed Books","version":"1.0","type":"link"}