{"product_id":"immunological-aspects-of-the-vascular-endothelium-hardback-9780521452496","title":"Immunological Aspects of the Vascular Endothelium (Hardback) 9780521452496","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eImmunological Aspects of the Vascular Endothelium\u003c\/font\u003e\u003cbr\u003e\r\n\r\n\r\n\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eAn 1995 look at the functioning of the vascular endothelium, and the diseases that arise as a result of inflammation and immunological responses.\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eCaroline O. S. Savage (Edited by), Jeremy D. Pearson (Edited by)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780521452496, Cambridge University Press\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 7 September 1995\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e276 pages\u003cbr\u003e23.7 x 15.8 x 2.4 cm, 0.594 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cem\u003e\u003cfont size=\"3\"\u003e\"This is a stimulating monograph...recommended for readers interested in the endothelium and its rapid ascendance to the status of an immunologic organ.\"   John A. Robinson, Doody's Health Sciences Book Review Journal\u003c\/font\u003e\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003eOriginally published in 1995, this volume looks at the functioning of the vascular endothelium, and the diseases and tissue injury that arise as a result of inflammation and immunological responses. The vascular endothelium is a metabolically highly active layer of cells lining all blood vessel walls. Through its interactions with leucocytes and other mediators, it is central to the development of inflammatory foci and to lymphocyte trafficking around the body. Tissue injury may arise here as a result of abnormal inflammatory or immune responses. The potential for such injury to contribute to autoimmune disease is discussed in this book, particularly in relation to autoimmune vascular disease of the renal, rheumatological and neurological systems, as well as in organ transplantation.\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e1. New concepts of mechanisms in autoimmunity\u003cbr\u003e 2. Regulation of endothelial cell function by cytokines\u003cbr\u003e 3. Interactions between granulocytes and endothelium\u003cbr\u003e 4. The regulation of lymphocyte migration by vascular endothelium and its role in the immune response\u003cbr\u003e 5. The role of the vascular endothelium in immunologically-mediated neurological diseases\u003cbr\u003e 6. The role of the endothelium in systemic lupus erythematosus and Sjögren's syndrome\u003cbr\u003e 7. The role of the endothelium in rheumatoid arthritis and scleroderma\u003cbr\u003e 8. The role of the endothelium in systemic vasculitis\u003cbr\u003e 9. Endothelial involvement in childhood Kawasaki disease\u003cbr\u003e 10. The role of the endothelium in thrombotic thrombocytopaenic purpura and haemolytic uraemic sydrome\u003cbr\u003e 11. The immunological role of the endothelium in organ transplantation\u003cbr\u003e Index.\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Immunology [\u003ca title=\"See our other books on Immunology\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Immunology%20%5BMJCM%5D%22\"\u003eMJCM\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Cambridge University Press","offers":[{"title":"Default Title","offer_id":46007493067032,"sku":"9780521452496","price":117.29,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/products\/9780521452496i_90074be6-55a1-448f-880b-465d7d676dd9.jpg?v=1691382245","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/immunological-aspects-of-the-vascular-endothelium-hardback-9780521452496","provider":"Freshly Printed Books","version":"1.0","type":"link"}