{"product_id":"homocysteine-in-health-and-disease-paperback-9781107402423","title":"Homocysteine in Health and Disease (Paperback \/ softback) 9781107402423","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eHomocysteine in Health and Disease\u003c\/font\u003e\u003cbr\u003e\r\n\r\n\r\n\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eThis is an unusually comprehensive 2001 account of the broad range of medical implications of homocysteine.\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eRalph Carmel (Edited by), Donald W. Jacobsen (Edited by)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9781107402423, Cambridge University Press\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003ePaperback \/ softback, published 21 July 2011\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e536 pages\u003cbr\u003e27.9 x 21 x 2.7 cm, 1.19 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cem\u003e\u003cfont size=\"3\"\u003eReview of the hardback: ' … a fascinating story, the authors are eminent in their fields and the coverage is authorititive and comprehensive. Here is an excellent reference book for anyone interested in the field. Given the important clinical, scientific, and policy issues raised by the folic acid association … geriatricians really need to know about homocysteine.' John Grimley Evans, Age and Aging\u003c\/font\u003e\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003eHigh levels of homocysteine have been identified as a very important risk factor in cardiovascular disease. Homocysteine-related abnormalities are also thought to contribute to birth defects and dementia, and there are many common acquired diseases, drugs and genetic disorders which adversely affect the metabolism of homocysteine. In this 2001 book a multidisciplinary team of experts in the field give a clear analysis of the biochemistry, genetics, epidemiology, clinical settings, causes, impact and treatment of homocysteine disorders. This is an unusually comprehensive account of the broad range of medical, nutritional and methodological implications of homocysteine in health and disease.\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e1. Introduction: historical overview and recent perspectives David Wilken and Bridget Wilken\u003cbr\u003e Part I. Biochemistry and Physiology\u003cbr\u003e Section I. Chemistry: 2. Practical chemistry of homocysteine and other thiols Donald W. Jacobsen\u003cbr\u003e 3. Biosynthesis and reactions of homocysteine thiolactone Hieronim Jakubowski\u003cbr\u003e 4. Homocysteine and lipid oxidation Jay W. Heinecke\u003cbr\u003e 5. Homocysteine, nitric oxide and nitrosothiols Andrew J. Gow, Fred Cobb and Jonathan S. Stamler\u003cbr\u003e Section II. Biochemistry and metabolism: 6. Biosynthesis of S-adenosylmethionine Jose M. Mato, Matias A. Avila and Fernado J. Corrales\u003cbr\u003e 7. S-adenosylmethionine-dependent methyltransferase Steven G. Clarke and Kelly Banfield\u003cbr\u003e 8. S-adenosylhomosysteine hydrolase Sean T. Prigge and Peter K. Chiang\u003cbr\u003e 9. Regulation of homocysteine metabolism James D. Finkelstein\u003cbr\u003e 10. Microbial modeling of human disease: homocysteine metabolism Rowena G. Matthews and Martha L. Ludwig\u003cbr\u003e 11. Folate metabolism Robert J. Cook\u003cbr\u003e 12. Cobalamin-dependent remethylation Ruma V. Banerjee and Horatiu Olteanu\u003cbr\u003e 13. Betaine-dependent remethylation Tim Garrow\u003cbr\u003e 14. The transsulfuration pathway Warren D. Kruger\u003cbr\u003e Section III. Physiology: 15. Cellular transport and tissue distribution Brian Fowler\u003cbr\u003e 16. Homocysteine and the kidney John T. Brosnan\u003cbr\u003e 17. Homocysteine and the nervous system Anne M. Molloy and Donald G. Weir\u003cbr\u003e Section IV. Clinical Chemistry: 18. Methodologies of testing Karsten Rasmussen and Jan Möller\u003cbr\u003e 19. Methionine loading Nicholas Dudman and Jonathan Silberberg\u003cbr\u003e Part II. Clinical Dysfunction and Hyperhomocysteinemia\u003cbr\u003e Section V. Genetic Disorders: 20. Cystathionine-ß-synthase and its deficiency Jan P. Kraus and Viktor Kozich\u003cbr\u003e 21. Inborn errors of folate and cobalamin metabolism David S. Rosenblatt\u003cbr\u003e 22. Polymorphisms of folate and cobalamin metabolism Rima Rozen\u003cbr\u003e Section VI. Acquired Disorders: 23. Folate deficiency Ralph Carmel\u003cbr\u003e 24. Cobalamin deficiency Ralph Carmel\u003cbr\u003e 25. Vitamin B6 deficiency Jesse F. Gregory III\u003cbr\u003e 26. Homocysteine in renal disease Margret Arnadottir and Björn Hultberg\u003cbr\u003e 27. Diseases and drugs associated with hyperhomocysteinemia Henk J. Blom\u003cbr\u003e 28. Lifestyle factors associated with hyperhomocysteinemia Stein Emil Vollset, Helga Refsum, Ottar Nygard and Per Ueland\u003cbr\u003e Section VII. Clinical Consequences of Hyperhomocysteinemia: 29. Epidemiology: vascular and thrombotic associations Petra Verhoef and Meir Stampfer\u003cbr\u003e 30. Homocysteine and coronary artery disease Killian Robinson\u003cbr\u003e 31. Homocysteine and cerebrovascular disease J. David Spence and James F. Toole\u003cbr\u003e 32. Peripheral arterial disease Godfried Boers\u003cbr\u003e 33. Venous disease Armando D'Angelo and Chiara Beltrametti\u003cbr\u003e 34. Homocysteine and hemostasis Katherine A. Hajjar\u003cbr\u003e 35. Cellular mechanisms of homocysteine pathogenesis in atherosclerosis Donald W. Jacobsen\u003cbr\u003e 36. Homocysteine and cardiovascular physiology Steven R. Lentz\u003cbr\u003e 37. Homocysteine and human reproduction T. K. A. B. Eskes\u003cbr\u003e Section VIII. Intervention and Therapy: 38. Modification of hyperhomocysteinemia John M. Scott\u003cbr\u003e 39. Design of clinical trials to test the homocysteine hypothesis of vascular disease Robert Clarke\u003cbr\u003e 40. What is a desirable homocysteine level? Johan B. Ubbink\u003cbr\u003e Index.\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Psychiatry [\u003ca title=\"See our other books on Psychiatry\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Psychiatry%20%5BMMH%5D%22\"\u003eMMH\u003c\/a\u003e], Haematology [\u003ca title=\"See our other books on Haematology\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Haematology%20%5BMJF%5D%22\"\u003eMJF\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Cambridge University Press","offers":[{"title":"Default Title","offer_id":46265682821400,"sku":"9781107402423","price":86.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/products\/9781107402423i.jpg?v=1694484846","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/homocysteine-in-health-and-disease-paperback-9781107402423","provider":"Freshly Printed Books","version":"1.0","type":"link"}