{"product_id":"her2-positive-breast-cancer-paperback-9780323581226","title":"HER2-Positive Breast Cancer (Paperback \/ softback) 9780323581226","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eHER2-Positive Breast Cancer\u003c\/font\u003e\u003cbr\u003e\r\n\r\n\r\n\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cp\u003eStay up to date with all aspects of HER2-positive breast cancer\u003c\/p\u003e\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eSara Hurvitz (Author), Kelly McCann (Author)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780323581226, Elsevier Health Sciences\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003ePaperback \/ softback, published 2 August 2018\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e264 pages, 100 illustrations (100 in full color)\u003cbr\u003e23.4 x 19 x 1.8 cm, 0.66 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003e\u003cp\u003eGet a quick, expert overview of clinically-focused topics and guidelines that are relevant to testing for HER2, which contributes to approximately 25% of breast cancers today. This concise resource by Drs. Sara Hurvitz, and Kelly McCann consolidates today’s available information on this growing topic into one convenient resource, making it an ideal, easy-to-digest reference for practicing and trainee oncologists.\u003c\/p\u003e\n\u003cul\u003e \u003cli\u003eCovers the diagnosis, treatments and targeted therapies, and management of breast cancers that are HER2-positive.\u003c\/li\u003e  \u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eContains sections on background and testing, advanced disease, therapeutics, and toxicity considerations.\u003c\/li\u003e \u003cli\u003eIncludes a timely section on innovative future therapies.\u003c\/li\u003e\n\u003c\/ul\u003e\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e\u003cb\u003eBackground\/testing\u003c\/b\u003e  \u003cp\u003e1. The HER2 alteration in breast cancer\u003ci\u003e\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2. HER2 testing in the era of changing guidelines\u003ci\u003e\u003c\/i\u003e\u003c\/p\u003e \u003cb\u003e \u003c\/b\u003e\u003cp\u003eAdvanced Disease\u003c\/p\u003e \u003cp\u003e3. Optimal first-line treatment of HER2+ advanced disease\u003ci\u003e\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4. Second line therapy and beyond\u003ci\u003e\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5. HER2+ CNS metastases\u003ci\u003e\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eTherapeutics\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e6. Neoadjuvant therapy\u003ci\u003e\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7. Adjuvant therapy\u003ci\u003e\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8. Outcomes based on HR status in early stage disease\u003ci\u003e\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9. De-escalation of therapy for small tumor\u003ci\u003e\u003c\/i\u003e\u003c\/p\u003e \u003cb\u003e \u003c\/b\u003e\u003cp\u003eToxicity considerations\u003c\/p\u003e \u003cp\u003e10. Cardiac toxicity of HER2-targeted regimens\u003ci\u003e\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e11. Non-cardiac toxicity of HER2-targeted therapy\u003ci\u003e\u003c\/i\u003e\u003c\/p\u003e \u003cb\u003e \u003c\/b\u003e\u003cp\u003eTherapies on the horizon\u003c\/p\u003e \u003cp\u003e12. Targeting other pathways active in HER2+ disease (CDK4\/6, VEGF, PI3K, mTOR, FGFR, PARP, antibody-drug conjugates, etc)\u003ci\u003e\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e13. Harnessing the immune system in HER2+ disease\u003ci\u003e\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e14. Biosimilars\u003ci\u003e\u003c\/i\u003e\u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Oncology [\u003ca title=\"See our other books on Oncology\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Oncology%20%5BMJCL%5D%22\"\u003eMJCL\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Elsevier","offers":[{"title":"Default Title","offer_id":46650450182424,"sku":"9780323581226","price":62.85,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/products\/9780323581226_0b9f30d7-9116-47cc-ba5c-2846112f1d9e.jpg?v=1694989966","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/her2-positive-breast-cancer-paperback-9780323581226","provider":"Freshly Printed Books","version":"1.0","type":"link"}