{"product_id":"gpcr-signaling-in-cancer-hardback-9780128202302","title":"GPCR Signaling in Cancer (Hardback) 9780128202302","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eGPCR Signaling in Cancer\u003c\/font\u003e\u003cbr\u003e\r\n\r\n\r\n\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cp\u003ePresents emerging concepts in targeting GPCRs for anti-cancer therapeutics\u003c\/p\u003e\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eArun K. Shukla (Volume editor)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780128202302, Elsevier Science\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 21 February 2020\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e164 pages\u003cbr\u003e22.9 x 15.1 x 1.8 cm, 0.41 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003e\u003cp\u003e\u003ci\u003eGPCR Signaling in Cancer, Volume 145\u003c\/i\u003e\u003ci\u003e,\u003c\/i\u003e the latest release in the \u003ci\u003eAdvances in Cancer Research\u003c\/i\u003e series, highlights recent developments in the area of GPCRs and cancer biology. Chapters included in this volume cover several GPCRs and their downstream effectors as case examples to highlight their fundamental understanding and therapeutic potential. Specific chapters address the Role of GRKs and beta-arrestins in cancer, Atypical GPCRs in cancer, the Role of a chemokine receptor (CCR) 5 in cancer, Targeting G protein-coupled receptors for therapeutics in cancer, Emerging GPCR signaling pathways in cancer, and more. \u003c\/p\u003e  \u003cp\u003eG protein-coupled receptors (GPCRs) constitute a large family of cell surface receptors which are involved in nearly every cellular and physiological event. These receptors can recognize a broad array of ligands and they are targeted by nearly one third of the currently prescribed drugs including anti-cancer therapeutics. \u003c\/p\u003e\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e\u003cp\u003e1. HERs Transregulation in Cancer Progression: From Discovery to 2020 and Beyond \u003ci\u003eRakesh Kumar \u003c\/i\u003e2. RTKs in Cancer Biology \u003ci\u003ePaul Fisher \u003c\/i\u003e3. Advances in EGFR Biochemistry and Biology \u003ci\u003eYosef Yarden \u003c\/i\u003e4. Mouse Models of RTKs\/HERs: Lessons and Implications to Biology and Therapy \u003ci\u003eWilliam Joseph Muller \u003c\/i\u003e5. MET Receptor in Oncology: From Biomarker to Therapeutic Target \u003ci\u003eRavi Salgia \u003c\/i\u003e6. RTKs in Pathobiology of Head \u0026amp; Neck Cancer \u003ci\u003eRadhakrishna Pillai \u003c\/i\u003e7. HER2 or Nuclear HER\/RTK in Cancer \u003ci\u003eMien-Chie Hung \u003c\/i\u003e8. FLT3 in Hematopietic Malignancies: From Pathobiology to Therapeutics \u003ci\u003ePremkumar Reddy \u003c\/i\u003e9. Advances in IGF1R Biology and –directed Cancer Therapeutics \u003ci\u003eDouglas Yee \u003c\/i\u003e10. Advances in Bcr-Abl in Cancer Therapy and Biology \u003ci\u003eNandini Verma \u003c\/i\u003e11. EphRs in Cancer Development and Progression \u003ci\u003eRenata Pasqualini \u003c\/i\u003e12. RTK-directed Clinical Advances: Trials and Treatments \u003ci\u003eMasakazu Toi\u003c\/i\u003e\u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Virology [\u003ca title=\"See our other books on Virology\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Virology%20%5Bnon-medical%5D%20%5BPSGL%5D%22\"\u003enon-medical PSGL\u003c\/a\u003e], Cellular biology [\u003ca title=\"See our other books on Cellular biology\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Cellular%20biology%20%5Bcytology%5D%20%5BPSF%5D%22\"\u003ecytology PSF\u003c\/a\u003e], Genetics [\u003ca title=\"See our other books on Genetics\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Genetics%20%5Bnon-medical%5D%20%5BPSAK%5D%22\"\u003enon-medical PSAK\u003c\/a\u003e], Immunology [\u003ca title=\"See our other books on Immunology\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Immunology%20%5BMJCM%5D%22\"\u003eMJCM\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Academic Press","offers":[{"title":"Default Title","offer_id":46650168901912,"sku":"9780128202302","price":119.19,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/products\/9780128202302.jpg?v=1694106160","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/gpcr-signaling-in-cancer-hardback-9780128202302","provider":"Freshly Printed Books","version":"1.0","type":"link"}