{"product_id":"genome-scale-algorithm-design-biological-sequence-analysis-in-the-era-of-high-throughput-sequencing-hardback-9781107078536","title":"Genome-Scale Algorithm Design; Biological Sequence Analysis in the Era of High-Throughput Sequencing (Hardback) 9781107078536","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eGenome-Scale Algorithm Design\u003c\/font\u003e\u003cbr\u003e\r\n\u003cfont size=\"5\"\u003eBiological Sequence Analysis in the Era of High-Throughput Sequencing\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cem\u003eProvides an integrated picture of the latest developments in algorithmic techniques, with numerous worked examples, algorithm visualisations and exercises.\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eVeli Mäkinen (Author), Djamal Belazzougui (Author), Fabio Cunial (Author), Alexandru I. Tomescu (Author)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9781107078536, Cambridge University Press\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 7 May 2015\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e413 pages, 90 b\/w illus.  4 tables  269 exercises\u003cbr\u003e25.3 x 18 x 2.2 cm, 0.96 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cem\u003e\u003cfont size=\"3\"\u003e'A very timely textbook covering many recently established techniques and applications at a level of rigor befitting a computer science audience.' Paul Medvedev, Pennsylvania State University\u003c\/font\u003e\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003eHigh-throughput sequencing has revolutionised the field of biological sequence analysis. Its application has enabled researchers to address important biological questions, often for the first time. This book provides an integrated presentation of the fundamental algorithms and data structures that power modern sequence analysis workflows. The topics covered range from the foundations of biological sequence analysis (alignments and hidden Markov models), to classical index structures (k-mer indexes, suffix arrays and suffix trees), Burrows–Wheeler indexes, graph algorithms and a number of advanced omics applications. The chapters feature numerous examples, algorithm visualisations, exercises and problems, each chosen to reflect the steps of large-scale sequencing projects, including read alignment, variant calling, haplotyping, fragment assembly, alignment-free genome comparison, transcript prediction and analysis of metagenomic samples. Each biological problem is accompanied by precise formulations, providing graduate students and researchers in bioinformatics and computer science with a powerful toolkit for the emerging applications of high-throughput sequencing.\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eNotation\u003cbr\u003e Preface\u003cbr\u003e Part I. Preliminaries: 1. Molecular biology and high-throughput sequencing\u003cbr\u003e 2. Algorithm design\u003cbr\u003e 3. Data structures\u003cbr\u003e 4. Graphs\u003cbr\u003e 5. Network flows\u003cbr\u003e Part II. Fundamentals of Biological Sequence Analysis: 6. Alignments\u003cbr\u003e 7. Hidden Markov models (HMMs)\u003cbr\u003e Part III. Genome-Scale Index Structures: 8. Classical indexes\u003cbr\u003e 9. Burrows–Wheeler indexes\u003cbr\u003e Part IV. Genome-Scale Algorithms: 10. Read alignment\u003cbr\u003e 11. Genome analysis and comparison\u003cbr\u003e 12. Genome compression\u003cbr\u003e 13. Fragment assembly\u003cbr\u003e Part V. Applications: 14. Genomics\u003cbr\u003e 15. Transcriptomics\u003cbr\u003e 16. Metagenomics\u003cbr\u003e References\u003cbr\u003e Index.\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Biology, life sciences [\u003ca title=\"See our other books on Biology, life sciences\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Biology,%20life%20sciences%20%5BPS%5D%22\"\u003ePS\u003c\/a\u003e], Mathematics \u0026amp; science [\u003ca title=\"See our other books on Mathematics \u0026amp; science\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Mathematics%20\u0026amp;%20science%20%5BP%5D%22\"\u003eP\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Cambridge University Press","offers":[{"title":"Default Title","offer_id":46003157041432,"sku":"9781107078536","price":60.99,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/products\/9781107078536i.jpg?v=1694545963","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/genome-scale-algorithm-design-biological-sequence-analysis-in-the-era-of-high-throughput-sequencing-hardback-9781107078536","provider":"Freshly Printed Books","version":"1.0","type":"link"}