{"product_id":"from-structure-to-clinical-development-allosteric-modulation-of-g-protein-coupled-receptors-hardback-9780128201879","title":"From Structure to Clinical Development: Allosteric Modulation of G Protein-Coupled Receptors (Hardback) 9780128201879","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eFrom Structure to Clinical Development: Allosteric Modulation of G Protein-Coupled Receptors\u003c\/font\u003e\u003cbr\u003e\r\n\r\n\r\n\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cp\u003eProvides the authority and expertise of leading contributors who discuss advances in pharmacology\u003c\/p\u003e\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eChristopher J. Langmead (Volume editor)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780128201879, Elsevier Science\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 8 May 2020\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e328 pages\u003cbr\u003e22.9 x 15.1 x 2.4 cm, 0.66 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003e\u003cp\u003e\u003ci\u003eFrom Structure to Clinical Development: Allosteric Modulation of G Protein-Coupled Receptors,\u003c\/i\u003e\u003ci\u003e Volume 88\u003c\/i\u003e\u003ci\u003e,\u003c\/i\u003e the latest release in the \u003ci\u003eAdvances in Pharmacology\u003c\/i\u003e series, presents a variety of chapters from the best authors in the field. Chapters in this updated edition include Targeting muscarinic M1 receptor in neurodegeneration, Photo-switchable allosteric ligands, Computational approaches for the design of mGlu receptor allosteric modulators, Allosteric modulation of GLP-1 receptor in metabolic disorders, Group II mGluR roles in the nervous system and their roles in addiction, RAMPs as allosteric modulators of Class B GPCRs, Structure-based discovery and development of mGlu5 NAMs, and much more. \u003c\/p\u003e\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e\u003col\u003e \u003col\u003e\n\u003cb\u003e \u003cli\u003eThe computational modeling of allosteric modulation of metabotropic glutamate receptors\u003c\/li\u003e\u003c\/b\u003e\u003ci\u003e \u003c\/i\u003e\u003cp\u003eLaura Pérez-Benito, Claudia Llinas del Torrent, Leonardo Pardo and Gary Tresadern\u003c\/p\u003e \u003cb\u003e \u003c\/b\u003e\u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eStructure-based discovery and development of metabotropic glutamate receptor 5 negative allosteric modulators\u003c\/li\u003e \u003ci\u003e \u003c\/i\u003e\u003cp\u003eKirstie A. Bennett, John A. Christopher and Benjamin G. Tehan\u003c\/p\u003e \u003cb\u003e \u003c\/b\u003e\u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eThe function and allosteric control of the human sweet taste receptor\u003c\/li\u003e \u003ci\u003e \u003c\/i\u003e\u003cp\u003eGuy Servant, Terry Kenakin, Lan Zhang, Mark Williams and Nicole Servant\u003c\/p\u003e \u003cb\u003e \u003c\/b\u003e\u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eThe different aspects of the GABA\u003csub\u003eB\u003c\/sub\u003e receptor allosteric modulation\u003c\/li\u003e \u003ci\u003e \u003c\/i\u003e\u003cp\u003eJulie Kniazeff\u003c\/p\u003e \u003cb\u003e \u003c\/b\u003e\u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eRAMPs as allosteric modulators of the calcitonin and calcitonin-like class B G protein-coupled receptors\u003c\/li\u003e \u003ci\u003e \u003c\/i\u003e\u003cp\u003eAugen A. Pioszak and Debbie L. Hay\u003c\/p\u003e \u003cb\u003e \u003c\/b\u003e\u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eStrategies and considerations of G-protein-coupled receptor photopharmacology\u003c\/li\u003e \u003ci\u003e \u003c\/i\u003e\u003cp\u003eAlice E. Berizzi and Cyril Goudet\u003c\/p\u003e \u003cb\u003e \u003c\/b\u003e\u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eDiscovery and pharmacology of the covalent GLP-1 receptor (GLP-1R) allosteric modulator BETP. A novel tool to probe GLP-1R pharmacology\u003c\/li\u003e \u003ci\u003e \u003c\/i\u003e\u003cp\u003eFrancis S. Willard, Joseph D. Ho and Kyle W. Sloop\u003c\/p\u003e \u003cb\u003e \u003c\/b\u003e\u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eAllosteric modulation of metabotropic glutamate receptors in alcohol use disorder: Insights from preclinical investigations\u003c\/li\u003e \u003ci\u003e \u003c\/i\u003e\u003cp\u003eKari A. Johnson and David M. Lovinger\u003c\/p\u003e \u003cb\u003e \u003c\/b\u003e\u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eAllosteric modulation of muscarinic receptors in alcohol and substance use disorders\u003c\/li\u003e \u003ci\u003e \u003c\/i\u003e\u003cp\u003eLeigh C. Walker and Andrew J. Lawrence\u003c\/p\u003e \u003cb\u003e \u003c\/b\u003e\u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eM1 muscarinic acetylcholine receptors: A therapeutic strategy for symptomatic and disease-modifying effects in Alzheimer's disease?\u003c\/li\u003e \u003c\/ol\u003e\n\u003c\/ol\u003e\n\u003ci\u003e \u003c\/i\u003e\u003cp\u003eMiriam Scarpa, Sarah Hesse and Sophie J. Bradley\u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Pharmacology [\u003ca title=\"See our other books on Pharmacology\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Pharmacology%20%5BMMG%5D%22\"\u003eMMG\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Academic Press","offers":[{"title":"Default Title","offer_id":46650168574232,"sku":"9780128201879","price":164.19,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/products\/9780128201879.jpg?v=1694106156","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/from-structure-to-clinical-development-allosteric-modulation-of-g-protein-coupled-receptors-hardback-9780128201879","provider":"Freshly Printed Books","version":"1.0","type":"link"}