{"product_id":"force-microscopy-applications-in-biology-and-medicine-hardback-9780471396284","title":"Force Microscopy; Applications in Biology and Medicine (Hardback) 9780471396284","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eForce Microscopy\u003c\/font\u003e\u003cbr\u003e\r\n\u003cfont size=\"5\"\u003eApplications in Biology and Medicine\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eBhanu P. Jena (Edited by), BP Jena (Author), J. K. Heinrich Hörber (Edited by)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780471396284, Wiley\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 15 August 2006\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e310 pages\u003cbr\u003e25.8 x 18.2 x 2.8 cm, 0.719 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003eA complete examination of the uses of the atomic force microscope in biology and medicine\u003cbr\u003e \u003cbr\u003e \u003cbr\u003e This cutting-edge text, written by a team of leading experts, is the first detailed examination of the latest, most powerful scanning probe microscope, the atomic force microscope (AFM). Using the AFM, in combination with conventional tools and techniques, readers gain a profound understanding of the cell, subcellular organelles, and biomolecular structure and function.\u003cbr\u003e \u003cbr\u003e The text begins with three chapters describing the molecular machinery and mechanism of cell secretion and membrane fusion in cells, using approaches that combine AFM, electron microscopy, X-ray diffraction, photon correlation spectroscopy, molecular biology, biochemistry, and electrophysiology. The discovery of a new cellular structure the \"porosome\" or fusion pore--the cells secretory machinery, the molecular mechanism of membrane fusion in cells, and the expulsion of intravesicular contents during cell secretion are outlined in the first three chapters. The book also covers:\u003cbr\u003e * Identification of the \"porosome\" in the growth hormone secreting cell of the pituitary gland\u003cbr\u003e * Probing the structural and physical properties of microbial cell surfaces\u003cbr\u003e * Scanning probe microscopic characterization of the higher plant cell wall and its components\u003cbr\u003e * Case studies of nano drug delivery systems using engineered dendrimers\u003cbr\u003e * AFM techniques for studying living cells\u003cbr\u003e * Investigating the intermolecular forces of leukocyte adhesion molecules\u003cbr\u003e * Protein-protein interactions\u003cbr\u003e * Micromechanical properties of lipid bilayers and vesicles\u003cbr\u003e \u003cbr\u003e The text concludes with four chapters that examine new and emerging approaches in the use of force microscopy in biology and medicine.\u003cbr\u003e \u003cbr\u003e This text is ideal for advanced undergraduate and graduate students and researchers in cell and molecular biology, genetics, genomics, physiology, neuroscience, biophysics, and biochemistry. Not only does it provide the theory, but also practical considerations such as the selection of the right tools and approach.\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003ePreface.  \u003cp\u003eContributors.\u003c\/p\u003e \u003cp\u003eChapter 1. Porosome: The Universal Secretory Machinery in Cells (\u003ci\u003eBhanu P. Jena\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003eChapter 2. Molecular Mechanism of SNARE-Induced Membrane Fusion (\u003ci\u003eBhanu P. Jena\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003eChapter 3. Molecular Mechanism of Secretory Vesicle Content Expulsion During Cell Secretion (\u003ci\u003eBhanu P. Jena\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003eChapter 4. Fusion Pores in Growth-Hormone-Secreting Cells of the Pituitary Gland: An AFM Study (\u003ci\u003eLloyd L. Anderson and Bhanu P. Jena\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003eChapter 5. Properties of Microbial Cell Surfaces Examined by Atomic Force Microscopy (\u003ci\u003eYves F. Dufre\u0026amp;ncirc;e\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003eChapter 6. Scanning Probe Microscopy of Plant Cell Wall and Its Constituents (\u003ci\u003eKsenija Radoti\u0026amp;cacute;, Miodrag Mi\u0026amp;cacute;i\u0026amp;cacute;, and Milorad Jeremi\u0026amp;cacute;\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003eChapter 7. Cellular Interactions of Nano Drug Delivery Systems (\u003ci\u003eRangaramanujam M. Kannan, Omathanu Pillai Perumal, and Sujatha Kannan\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003eChapter 8. Adapting AFM Techniques for Studies on Living Cells (J\u003ci\u003e. K. Heinrich Hörber\u003c\/i\u003e)\u003c\/p\u003e \u003cp\u003eChapter 9. Intermolecular Forces of Leukocyte Adhesion Molecules (\u003ci\u003eXiaohui Zhang and Vincent T. Moy\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003eChapter 10. Mechanisms of Avidity Modulation in Leukocyte Adhesion Studied by AFM (\u003ci\u003eEwa P. Wojcikiewicz and Vincent T. Moy\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003eChapter 11. Resolving the Thickness and Micromechanical Properties of Lipid Bilayers and Vesicles Using AFM (\u003ci\u003eGuangzhao Mao and Xuemei Liang\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003eChapter 12. Imaging Soft Surfaces by SFM (\u003ci\u003eAndreas Janke and Tilo Pompe\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003eChapter 13. High-Speed Atomic Force Microscopy of Biomolecules in Motion (\u003ci\u003eTilman E. Schäffer\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003eChapter 14. Atomic Force Microscopy in Cytogenetics (\u003ci\u003eS. Thalhammer and W. M. Heckl\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003eChapter 15. Atomic Force Microscopy in the Study of Macromolecular Interactions in Hemostasis and Thrombosis: Utility for Investigation of the Antiphospholipid Syndrome (\u003ci\u003eWilliam J. Montigny, Anthony S. Quinn, Xiao-Xuan Wu, Edwin G. Bovill, Jacob H. Rand, and Douglas J. Taatjes\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003eIndex\u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Biology, life sciences [\u003ca title=\"See our other books on Biology, life sciences\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Biology,%20life%20sciences%20%5BPS%5D%22\"\u003ePS\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Wiley-Liss","offers":[{"title":"Brand New","offer_id":52293467144472,"sku":"9780471396284","price":150.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/files\/9780471396284.jpg?v=1781640535","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/force-microscopy-applications-in-biology-and-medicine-hardback-9780471396284","provider":"Freshly Printed Books","version":"1.0","type":"link"}