{"product_id":"fluorescent-nanodiamonds-hardback-9781119477082","title":"Fluorescent Nanodiamonds (Hardback) 9781119477082","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eFluorescent Nanodiamonds\u003c\/font\u003e\u003cbr\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003c\/p\u003e\n\u003cp\u003e\u003cfont size=\"4\"\u003eHuan-Cheng Chang (Author), Wesley Wei-Wen Hsiao (Author), Meng-Chih Su (Author)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9781119477082, Wiley\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 16 November 2018\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e304 pages\u003cbr\u003e24.6 x 17.5 x 2 cm, 0.726 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003e\u003cp\u003e\u003cb\u003eThe most comprehensive reference on fluorescent nanodiamond physical and chemical properties and contemporary applications\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eFluorescent nanodiamonds (FNDs) have drawn a great deal of attention over the past several years, and their applications and development potential are proving to be manifold and vast. The first and only book of its kind, \u003ci\u003eFluorescent Nanodiamonds\u003c\/i\u003e is a comprehensive guide to the basic science and technical information needed to fully understand the fundamentals of FNDs and their potential applications across an array of domains. In demonstrating the importance of FNDs in biological applications, the authors bring together all relevant chemistry, physics, materials science and biology.\u003c\/p\u003e \u003cp\u003eNanodiamonds are produced by powerful cataclysmic events such as explosions, volcanic eruptions and meteorite impacts. They also can be created in the lab by high-pressure high-temperature treatment of graphite or detonating an explosive in a reactor vessel. A single imperfection can give a nanodiamond a specific, isolated color center which allows it to function as a single, trapped atom. Much smaller than the thickness of a human hair, a nanodiamond can have a huge surface area that allows it to bond with a variety of other materials. Because of their non-toxicity, nanodiamonds may be useful in biomedical applications, such as drug delivery and gene therapy. \u003c\/p\u003e \u003cul\u003e \u003cli\u003eThe most comprehensive reference on a topic of rapidly increasing interest among academic and industrial researchers across an array of fields\u003c\/li\u003e \u003cli\u003eIncludes numerous case studies and practical examples from many areas of research and industrial applications, as well as fascinating and instructive historical perspectives\u003c\/li\u003e \u003cli\u003eEach chapter addresses, in-depth, a single integral topic including the fundamental properties, synthesis, mechanisms and functionalisation of FNDs\u003c\/li\u003e \u003cli\u003eThe first book published by the key patent holder with his research group in the field of FNDs\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003e\u003ci\u003eFluorescent Nanodiamonds\u003c\/i\u003e is an important working resource for a broad range of scientists and engineers in industry and academia. It will also be a welcome reference for instructors in chemistry, physics, materials science, biology and related fields.\u003c\/p\u003e\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e\u003cp\u003ePreface xi\u003c\/p\u003e \u003cp\u003eAcknowledgements xv\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart I Basics 1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 Introduction to Nanotechnology 3\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1.1 Nanotechnology: From Large to Small 3\u003c\/p\u003e \u003cp\u003e1.1.1 Feynman: Plenty of Room at the Bottom 3\u003c\/p\u003e \u003cp\u003e1.1.2 Nanotechnology Today 6\u003c\/p\u003e \u003cp\u003e1.1.3 The Bottom‐Up Approach 7\u003c\/p\u003e \u003cp\u003e1.2 Nanocarbons: Now and Then 8\u003c\/p\u003e \u003cp\u003e1.2.1 Classification 9\u003c\/p\u003e \u003cp\u003e1.2.2 Fullerenes 9\u003c\/p\u003e \u003cp\u003e1.2.3 Carbon Nanotubes 11\u003c\/p\u003e \u003cp\u003e1.2.4 Graphenes 13\u003c\/p\u003e \u003cp\u003eReferences 15\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 Nanodiamonds 19\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e2.1 Ah, Diamonds, Eternal Beautiful 19\u003c\/p\u003e \u003cp\u003e2.2 Diamonds: From Structure to Classification 22\u003c\/p\u003e \u003cp\u003e2.2.1 Structure 22\u003c\/p\u003e \u003cp\u003e2.2.2 Classification 24\u003c\/p\u003e \u003cp\u003e2.3 Diamond Synthesis 26\u003c\/p\u003e \u003cp\u003e2.3.1 HPHT 27\u003c\/p\u003e \u003cp\u003e2.3.2 CVD 29\u003c\/p\u003e \u003cp\u003e2.3.3 Detonation 30\u003c\/p\u003e \u003cp\u003e2.4 Nanodiamonds: A Scientist’s Best Friend 30\u003c\/p\u003e \u003cp\u003eReferences 33\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Color Centers in Diamond 37\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e3.1 Nitrogen Impurities 37\u003c\/p\u003e \u003cp\u003e3.2 Crystal Defects 40\u003c\/p\u003e \u003cp\u003e3.3 Vacancy‐Related Color Centers 41\u003c\/p\u003e \u003cp\u003e3.3.1 GR1 and ND1 41\u003c\/p\u003e \u003cp\u003e3.3.2 NV\u003csup\u003e0\u003c\/sup\u003e and NV\u003csup\u003e−\u003c\/sup\u003e 44\u003c\/p\u003e \u003cp\u003e3.3.3 H3 and N3 46\u003c\/p\u003e \u003cp\u003e3.3.4 SiV\u003csup\u003e−\u003c\/sup\u003e 46\u003c\/p\u003e \u003cp\u003e3.4 The NV\u003csup\u003e−\u003c\/sup\u003e Center 47\u003c\/p\u003e \u003cp\u003eReferences 50\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Surface Chemistry of Nanodiamonds 55\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e4.1 Functionalization 56\u003c\/p\u003e \u003cp\u003e4.2 Bioconjugation 61\u003c\/p\u003e \u003cp\u003e4.2.1 Noncovalent Conjugation 61\u003c\/p\u003e \u003cp\u003e4.2.2 Covalent Conjugation 64\u003c\/p\u003e \u003cp\u003e4.3 Encapsulation 66\u003c\/p\u003e \u003cp\u003e4.3.1 Lipid Layers 66\u003c\/p\u003e \u003cp\u003e4.3.2 Silica Shells 67\u003c\/p\u003e \u003cp\u003eReferences 69\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Biocompatibility of Nanodiamonds 73\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e5.1 Biocompatibility Testing 73\u003c\/p\u003e \u003cp\u003e5.1.1 Cytotoxicity 74\u003c\/p\u003e \u003cp\u003e5.1.2 Genotoxicity 76\u003c\/p\u003e \u003cp\u003e5.1.3 Hemocompatibility 76\u003c\/p\u003e \u003cp\u003e5.2 \u003ci\u003eIn Vitro\u003c\/i\u003e Studies 77\u003c\/p\u003e \u003cp\u003e5.2.1 HPHT‐ND 77\u003c\/p\u003e \u003cp\u003e5.2.2 DND 80\u003c\/p\u003e \u003cp\u003e5.3 \u003ci\u003eEx Vivo\u003c\/i\u003e Studies 82\u003c\/p\u003e \u003cp\u003e5.4 \u003ci\u003eIn Vivo\u003c\/i\u003e Studies 83\u003c\/p\u003e \u003cp\u003eReferences 86\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePart II Specific Topics 91\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 Producing Fluorescent Nanodiamonds 93\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e6.1 Production 93\u003c\/p\u003e \u003cp\u003e6.1.1 Theoretical Simulations 93\u003c\/p\u003e \u003cp\u003e6.1.2 Electron\/Ion Irradiation 96\u003c\/p\u003e \u003cp\u003e6.1.3 Size Reduction 99\u003c\/p\u003e \u003cp\u003e6.2 Characterization 101\u003c\/p\u003e \u003cp\u003e6.2.1 Fluorescence Intensity 101\u003c\/p\u003e \u003cp\u003e6.2.2 Electron Spin Resonance 104\u003c\/p\u003e \u003cp\u003e6.2.3 Fluorescence Lifetime 105\u003c\/p\u003e \u003cp\u003e6.2.4 Magnetically Modulated Fluorescence 107\u003c\/p\u003e \u003cp\u003eReferences 110\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 Single Particle Detection and Tracking 113\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e7.1 Single Particle Detection 113\u003c\/p\u003e \u003cp\u003e7.1.1 Photostability 113\u003c\/p\u003e \u003cp\u003e7.1.2 Spectroscopic Properties 117\u003c\/p\u003e \u003cp\u003e7.1.3 Color Center Numbers 118\u003c\/p\u003e \u003cp\u003e7.2 Single Particle Tracking 120\u003c\/p\u003e \u003cp\u003e7.2.1 Tracking in Solution 120\u003c\/p\u003e \u003cp\u003e7.2.2 Tracking in Cells 122\u003c\/p\u003e \u003cp\u003e7.2.3 Tracking in Organisms 127\u003c\/p\u003e \u003cp\u003eReferences 130\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 Cell Labeling and Fluorescence Imaging 135\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e8.1 Cell Labeling 135\u003c\/p\u003e \u003cp\u003e8.1.1 Nonspecific Labeling 136\u003c\/p\u003e \u003cp\u003e8.1.2 Specific Labeling 139\u003c\/p\u003e \u003cp\u003e8.2 Fluorescence Imaging 142\u003c\/p\u003e \u003cp\u003e8.2.1 Epifluorescence and Confocal Fluorescence 142\u003c\/p\u003e \u003cp\u003e8.2.2 Total Internal Reflection Fluorescence 144\u003c\/p\u003e \u003cp\u003e8.2.3 Two‐Photon Excitation Fluorescence 146\u003c\/p\u003e \u003cp\u003e8.2.4 Time‐Gated Fluorescence 147\u003c\/p\u003e \u003cp\u003eReferences 150\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 Cell Tracking and Deep Tissue Imaging 155\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e9.1 Cellular Uptake 155\u003c\/p\u003e \u003cp\u003e9.1.1 Uptake Mechanism 155\u003c\/p\u003e \u003cp\u003e9.1.2 Entrapment 158\u003c\/p\u003e \u003cp\u003e9.1.3 Quantification 159\u003c\/p\u003e \u003cp\u003e9.2 Cell Tracking 161\u003c\/p\u003e \u003cp\u003e9.2.1 Tracking \u003ci\u003eIn Vitro\u003c\/i\u003e 161\u003c\/p\u003e \u003cp\u003e9.2.2 Tracking \u003ci\u003eIn Vivo\u003c\/i\u003e 163\u003c\/p\u003e \u003cp\u003e9.3 Deep Tissue Imaging 165\u003c\/p\u003e \u003cp\u003e9.3.1 Wide‐Field Fluorescence Imaging 165\u003c\/p\u003e \u003cp\u003e9.3.2 Optically Detected Magnetic Resonance Imaging 169\u003c\/p\u003e \u003cp\u003e9.3.3 Time‐Gated Fluorescence Imaging 170\u003c\/p\u003e \u003cp\u003e9.3.4 Magnetically Modulated Fluorescence Imaging 170\u003c\/p\u003e \u003cp\u003eReferences 171\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 Nanoscopic Imaging 175\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e10.1 Diffraction Barrier 176\u003c\/p\u003e \u003cp\u003e10.2 Superresolution Fluorescence Imaging 177\u003c\/p\u003e \u003cp\u003e10.2.1 Stimulated Emission Depletion Microscopy 177\u003c\/p\u003e \u003cp\u003e10.2.2 Saturated Excitation Fluorescence Microscopy 181\u003c\/p\u003e \u003cp\u003e10.2.3 Deterministic Emitter Switch Microscopy 182\u003c\/p\u003e \u003cp\u003e10.2.4 Tip‐Enhanced Fluorescence Microscopy 183\u003c\/p\u003e \u003cp\u003e10.3 Cathodoluminescence Imaging 184\u003c\/p\u003e \u003cp\u003e10.4 Correlative Light‐Electron Microscopy 188\u003c\/p\u003e \u003cp\u003eReferences 191\u003c\/p\u003e \u003cp\u003e\u003cb\u003e11 Nanoscale Quantum Sensing 195\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e11.1 The Spin Hamiltonian 196\u003c\/p\u003e \u003cp\u003e11.2 Temperature Sensing 197\u003c\/p\u003e \u003cp\u003e11.2.1 Ultrahigh Precision Temperature Measurement 197\u003c\/p\u003e \u003cp\u003e11.2.2 Time‐Resolved Nanothermometry 200\u003c\/p\u003e \u003cp\u003e11.2.3 All‐Optical Luminescence Nanothermometry 203\u003c\/p\u003e \u003cp\u003e11.2.4 Scanning Thermal Imaging 205\u003c\/p\u003e \u003cp\u003e11.3 Magnetic Sensing 207\u003c\/p\u003e \u003cp\u003e11.3.1 Continuous‐Wave Detection 207\u003c\/p\u003e \u003cp\u003e11.3.2 Relaxometry 210\u003c\/p\u003e \u003cp\u003eReferences 211\u003c\/p\u003e \u003cp\u003e\u003cb\u003e12 Hybrid Fluorescent Nanodiamonds 215\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e12.1 Silica\/Diamond Nanohybrids 215\u003c\/p\u003e \u003cp\u003e12.2 Gold\/Diamond Nanohybrids 217\u003c\/p\u003e \u003cp\u003e12.2.1 Photoluminescence Enhancement 217\u003c\/p\u003e \u003cp\u003e12.2.2 Dual‐Modality Imaging 218\u003c\/p\u003e \u003cp\u003e12.2.3 Hyperlocalized Hyperthermia 220\u003c\/p\u003e \u003cp\u003e12.2.4 NV‐Based Nanothermometry 224\u003c\/p\u003e \u003cp\u003e12.3 Silver\/Diamond Nanohybrids 226\u003c\/p\u003e \u003cp\u003e12.4 Iron Oxide\/Diamond Nanohybrids 228\u003c\/p\u003e \u003cp\u003e12.4.1 Single‐Domain Magnetization 228\u003c\/p\u003e \u003cp\u003e12.4.2 Magnetic Resonance Imaging 229\u003c\/p\u003e \u003cp\u003eReferences 232\u003c\/p\u003e \u003cp\u003e\u003cb\u003e13 Nanodiamond‐Enabled Medicine 235\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e13.1 NDs as Therapeutic Carriers 236\u003c\/p\u003e \u003cp\u003e13.2 Drug Delivery 237\u003c\/p\u003e \u003cp\u003e13.2.1 Small Molecules 237\u003c\/p\u003e \u003cp\u003e13.2.2 Proteins 241\u003c\/p\u003e \u003cp\u003e13.3 Gene Therapy 244\u003c\/p\u003e \u003cp\u003e13.3.1 RNA 244\u003c\/p\u003e \u003cp\u003e13.3.2 DNA 245\u003c\/p\u003e \u003cp\u003e13.4 Animal Experiments 247\u003c\/p\u003e \u003cp\u003eReferences 249\u003c\/p\u003e \u003cp\u003e14 Diamonds in the Sky 253\u003c\/p\u003e \u003cp\u003e14.1 Unidentified Infrared Emission 253\u003c\/p\u003e \u003cp\u003e14.2 Extended Red Emission 258\u003c\/p\u003e \u003cp\u003e14.3 Cosmic Events at Home on Earth 264\u003c\/p\u003e \u003cp\u003eReferences 267\u003c\/p\u003e \u003cp\u003eFurther Reading 271\u003c\/p\u003e \u003cp\u003eIndex 273\u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Mechanical engineering \u0026amp; materials [\u003ca title=\"See our other books on Mechanical engineering \u0026amp; materials\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Mechanical%20engineering%20\u0026amp;%20materials%20%5BTG%5D%22\"\u003eTG\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Wiley","offers":[{"title":"Brand New","offer_id":52428605292824,"sku":"9781119477082","price":95.59,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/files\/9781119477082.jpg?v=1784681179","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/fluorescent-nanodiamonds-hardback-9781119477082","provider":"Freshly Printed Books","version":"1.0","type":"link"}