{"product_id":"epigenetics-and-dna-damage-paperback-9780323910811","title":"Epigenetics and DNA Damage (Paperback \/ softback) 9780323910811","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eEpigenetics and DNA Damage\u003c\/font\u003e\u003cbr\u003e\r\n\r\n\r\n\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eProvides a comprehensive foundation in epigenetics and DNA damage, as well as informed discussion of evolving research trends, disease findings, early therapeutics, and protocols for further study\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eMiriam Galvonas Jasiulionis (Edited by)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780323910811, Elsevier Science\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003ePaperback \/ softback, published 25 August 2022\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e336 pages, 80 illustrations (40 in full color)\u003cbr\u003e23.5 x 19 x 2.2 cm, 0.68 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cem\u003e\u003cfont size=\"3\"\u003e\"Overall, I feel this is a great book for both investigators with no or limited experience in the field and for seasoned investigators planning to test a new hypothesis.\"\u003cb\u003e --Quarterly Review of Biology\u003c\/b\u003e\u003c\/font\u003e\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003e\u003cp\u003eAlthough scientists recognize the role of epigenetic mechanisms in DNA damage response, the complex, mechanistic interplay between chromatin regulation and DNA repair is still poorly understood. Comprehending how these processes are connected in time and space and play out in developmental processes may reveal novel directions for new research and disease treatment.\u003c\/p\u003e  \u003cp\u003e\u003ci\u003eEpigenetics and DNA Damage\u003c\/i\u003e, a new volume in the Translational Epigenetics series, offers a thorough grounding in the relationship between DNA Damage, epigenetic modifications, and chromatin regulation. Early chapters address the basic science of DNA damage and its association with various epigenetic mechanisms, including DNA methylation, post-translational histone modifications, histone variants, chromatin remodeling, miRNAs, and lncRNAs. This is followed by a close discussion of DNA damage and epigenetics in metabolism, aging, cellular differentiation, immune function, stem cell biology, and cancer, tying recent research to translational application in disease understanding. Later chapters examine possible epigenetic therapies combining DNA damage induction and epigenetic alteration, as well as instructive chapters on how to analyze DNA damage and epigenetic alterations in new research.\u003c\/p\u003e\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e1. Introduction Miriam Galvonas Jasiulionis\u003cbr\u003e2. DNA damage and DNA methylation\u003cbr\u003e3. DNA damage and histone modifications\u003cbr\u003e4. DNA damage and histone variants\u003cbr\u003e5. DNA damage and chromatin regulators\u003cbr\u003e6. DNA damage and miRNAs\u003cbr\u003e7. DNA damage and lncRNAs\u003cbr\u003e8. DNA damage, SIRT1 and epigenetic marks\u003cbr\u003e9. DNA damage, metabolic alterations and epigenetic changes\u003cbr\u003e10. DNA damage, diet and epigenetic changes\u003cbr\u003e11. DNA damage, epigenetics and aging\u003cbr\u003e12. DNA damage, epigenetics and pluripotent stem cell differentiation\u003cbr\u003e13. DNA damage, epigenetics and chronic inflammatory diseases\u003cbr\u003e14. DNA damage, epigenetic alterations and immune dysfunction\u003cbr\u003e15. DNA repair, epigenetics and trinucleotide repeat ataxias\u003cbr\u003e16. DNA damage, epigenetics and cancer\u003cbr\u003e17. Oncometabolites, epigenetic marks and DNA repair\u003cbr\u003e18. Therapies inducing DNA damage\u003cbr\u003e19. Epigenetic therapy\u003cbr\u003e20. Therapeutic strategies combining damage induction and epigenetic alterations\u003cbr\u003e21. Useful protocols to study DNA damage\u003cbr\u003e22. Useful protocols to study epigenetic modifications\u003cbr\u003e23. Interplay between DNA repair and epigenetics: Future directions\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: DNA \u0026amp; Genome [\u003ca title=\"See our other books on DNA \u0026amp; Genome\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22DNA%20\u0026amp;%20Genome%20%5BPSAK1%5D%22\"\u003ePSAK1\u003c\/a\u003e], Genetics [\u003ca title=\"See our other books on Genetics\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Genetics%20%5Bnon-medical%5D%20%5BPSAK%5D%22\"\u003enon-medical PSAK\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Academic Press","offers":[{"title":"Default Title","offer_id":46648886231320,"sku":"9780323910811","price":119.28,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/products\/9780323910811_89990e6c-656a-494f-8583-3a6d51dd708d.jpg?v=1694993384","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/epigenetics-and-dna-damage-paperback-9780323910811","provider":"Freshly Printed Books","version":"1.0","type":"link"}