{"product_id":"dyneins-the-biology-of-dynein-motors-hardback-9780128094716","title":"Dyneins; The Biology of Dynein Motors (Hardback) 9780128094716","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eDyneins\u003c\/font\u003e\u003cbr\u003e\r\n\u003cfont size=\"5\"\u003eThe Biology of Dynein Motors\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cem\u003e\u003cp\u003eCompletely updated version, covering all aspects of dyneins: structure, biology, and the application of scientific research to treat human disease\u003c\/p\u003e\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eStephen M. King (Edited by)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780128094716\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 22 November 2017\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e684 pages\u003cbr\u003e23.4 x 19 x 3.6 cm, 1.56 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003e\u003cp\u003e\u003ci\u003eDyneins: The Biology of Dynein Motors, Second Edition, \u003c\/i\u003eoffers a broad view of dyneins from structure, composition and organization, to biology of dynein function in both cytoplasm and cilia. As the second book in a pair on this topic, these works provide an overview of dyneins, from structure and function, to dysfunction and disease. Since the first edition, enormous strides have been taken in understanding dynein structure, its organization in the axoneme, single molecule motor mechanics and the consequences of defects for human biology, disease and development. This second edition is extensively revised, with coverage expanded from 24 to 42 chapters.\u003c\/p\u003e  \u003cp\u003eMuch of the expanded coverage occurs in Volume Two on dynein dysfunction and disease, such as the role of dynein and cancer, while Volume One covers the history and evolution of dyneins, dyneins in ciliary biology and cytoplasmic dynein biology. \u003c\/p\u003e\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e\u003cp\u003e\u003cb\u003eI. History and Evolution \u003c\/b\u003e1. Discovery of dynein and its properties: a personal account 2. Origins of cytoplasmic dynein 3. The evolutionary biology of dyneins\u003c\/p\u003e \u003cp\u003e\u003cb\u003eII.\u003c\/b\u003e \u003cb\u003eDyneins in Ciliary Biology \u003c\/b\u003e4. Cytoplasmic preassembly and trafficking of axonemal dyneins 5. Composition and assembly of axonemal dyneins 6. Organization of dyneins in the axoneme 7. Genetic approaches to axonemal dynein function in \u003ci\u003eChlamydomonas\u003c\/i\u003e and other organisms 8. Regulatory mechanics of outer arm dynein motors 9. Control of axonemal inner dynein arms 10. Ciliary and flagellar motility and the nexin-dynein regulatory complex 11. Regulation of dynein-driven ciliary and flagellar movement 12. Dynein-mediated photobehavioral responses in \u003ci\u003eChlamydomonas\u003c\/i\u003e 13. Dynein and intraflagellar transport\u003c\/p\u003e \u003cp\u003e\u003cb\u003eIII. Cytoplasmic Dynein Biology \u003c\/b\u003e14. Cytoplasmic dynein function defined by subunit composition 15. Regulation of cytoplasmic dynein motility 16. Insights into cytoplasmic dynein function and regulation from fungal genetics 17. Role of dynactin in dynein-mediated motility 18. Role of cytoplasmic dynein and dynactin in mitotic checkpoint silencing 19. Cytoplasmic dynein during mitosis 20. Dynein and dynactin at microtubule plus ends 21. Drosophila cytoplasmic dynein: mutations, tools and developmental functions\u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Cellular biology [\u003ca title=\"See our other books on Cellular biology\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Cellular%20biology%20%5Bcytology%5D%20%5BPSF%5D%22\"\u003ecytology PSF\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Freshly Printed Books","offers":[{"title":"Default Title","offer_id":46649746227480,"sku":"9780128094716","price":87.98,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/products\/9780128094716_dd2ad05f-db91-4e2e-8ba4-0d3b8753c672.jpg?v=1694353218","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/dyneins-the-biology-of-dynein-motors-hardback-9780128094716","provider":"Freshly Printed Books","version":"1.0","type":"link"}