{"product_id":"dna-engineered-noble-metal-nanoparticles-fundamentals-and-state-of-the-art-of-nanobiotechnology-hardback-9781118072141","title":"DNA Engineered Noble Metal Nanoparticles; Fundamentals and State-of-the-Art of Nanobiotechnology (Hardback) 9781118072141","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eDNA Engineered Noble Metal Nanoparticles\u003c\/font\u003e\u003cbr\u003e\r\n\u003cfont size=\"5\"\u003eFundamentals and State-of-the-Art of Nanobiotechnology\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eIgnác Capek (Author), Ashutosh Tiwari (Series edited by)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9781118072141, Wiley\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 26 May 2015\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e672 pages\u003cbr\u003e24.1 x 16.3 x 3.7 cm, 1.225 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003e\u003cp\u003eThere is a growing interest in the use of nanoparticles modified with DNAs, viruses, peptides and proteins for the rational design of nanostructured functional materials and their use in biosensor applications. The challenge is to control the organization of biomolecules on nanoparticles while retaining their biological activity as potential chemical and gene therapeutics. These noble metal nanoparticles\/biomolecules conjugates have specific properties and therefore they are attractive materials for nanotechnology in biochemistry and  medicine.\u003c\/p\u003e \u003cp\u003eIn this book, the author review work performed dealing with the DNA structure and functionalities, interactions between DNA, noble metal nanoparticles, surface active agents, solvents and other additives. Particular attention is given to how the DNA's chain length and the DNA conformation affect the interaction and structure of the nanoconjugates and nanostructures that are formed. Also discussed are the recent advances in the preparation, characterization, and applications of noble metal nanoparticles that are conjugated with DNA aptamers and oligomers. The advantages and disadvantages of functionalized nanoparticles through various detection modes are highlighted, including colorimetry, fluorescence, electrochemistry, SPR, and, mass spectrometry for the detection of small molecules and biomolecules. The functionalized noble metal nanoparticles are selective and sensitive for the analytes, showing their great potential in biosensing. Furthermore, this book reviews recent progress in the area of DNA-noble metal nanoparticles based artificial nanostructures, that is, the preparation, collective properties, and applications of various DNA-based nanostructures are also described.\u003c\/p\u003e\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e\u003cp\u003eAcknowledgement ix\u003c\/p\u003e \u003cp\u003ePreface xi\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 Introduction 1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 Nucleic Acids 29\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e2.1 DNA\/RNA Basics 29\u003c\/p\u003e \u003cp\u003e2.2 Aptamers, Telomers and Oligonucleotides 50\u003c\/p\u003e \u003cp\u003e2.3 Techniques and Approaches 63\u003c\/p\u003e \u003cp\u003e2.4 DNA-Based Molecular Nanomachines 90\u003c\/p\u003e \u003cp\u003e2.5 Peptide Nucleic Acid 104\u003c\/p\u003e \u003cp\u003e2.6 Nanobiotechnology 112\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Noble Metal Nanoparticles 121\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e3.1 Preparation and Modification 121\u003c\/p\u003e \u003cp\u003e3.2 Optical and Physical Properties 137\u003c\/p\u003e \u003cp\u003e3.3 Conjugates 144\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 DNA-Based Conjugates 149\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e4.1 General 149\u003c\/p\u003e \u003cp\u003e4.2 Condensation 152\u003c\/p\u003e \u003cp\u003e4.3 Conjugates 170\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 DNA-Noble Metal Nanoparticle Conjugates 173\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e5.1 General Approaches 173\u003c\/p\u003e \u003cp\u003e5.2 DNA Monomers and Oligomers 178\u003c\/p\u003e \u003cp\u003e5.2.1 Gold Nanoparticles 178\u003c\/p\u003e \u003cp\u003e5.2.2 Silver Nanoparticles 207\u003c\/p\u003e \u003cp\u003e5.3 Hybridization and Denaturation 224\u003c\/p\u003e \u003cp\u003e5.4 DNA Biotemplates 273\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 DNA-Gold Nanoparticle Conjugates 281\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e6.1 DNA-Gold Zero-Dimensional Nanoparticle Conjugates 281\u003c\/p\u003e \u003cp\u003e6.2 DNA One-Dimensional Gold Nanoparticle Conjugates 295\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 PNA-Noble Metal Nanoparticles Conjugates 315\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e7.1 PNA-Gold Nanoparticle Conjugates 315\u003c\/p\u003e \u003cp\u003e7.2 PNA-Silver Nanoparticle Conjugates 328\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 DNA-Silver Nanoparticles Conjugates 335\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 The Structure of DNA-Noble Metal Nanoparticles Conjugates 345\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e9.1 Configuration of DNA-Noble Metal Nanoparticles Conjugates 345\u003c\/p\u003e \u003cp\u003e9.2 Stabilization of DNA Conjugates 358\u003c\/p\u003e \u003cp\u003e9.3 Nanostructures and Nanoconstructs 369\u003c\/p\u003e \u003cp\u003e9.4 Colorimetric and Sensing Assays 385\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 Photochemical and Photophysical Events 403\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e10.1 Noble Metal Nanoparticles 403\u003c\/p\u003e \u003cp\u003e10.2 DNA Nucleobases 406\u003c\/p\u003e \u003cp\u003e10.3 DNA\/PNA 417\u003c\/p\u003e \u003cp\u003e10.4 DNA-Dyes Conjugates 429\u003c\/p\u003e \u003cp\u003e10.5 DNA-AuNP-Dye Conjugates 443\u003c\/p\u003e \u003cp\u003e10.6 DNA-Gold Nanoparticle Conjugates 455\u003c\/p\u003e \u003cp\u003e10.7 DNA-AgNPs 465\u003c\/p\u003e \u003cp\u003e10.8 Hot Gold Nanoparticles 475\u003c\/p\u003e \u003cp\u003e\u003cb\u003e11 Nanoparticle Therapeutics 481\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e11.1 Biodecorated Nanoparticle-Based Therapies 481\u003c\/p\u003e \u003cp\u003e11.2 Photothermal Therapy 489\u003c\/p\u003e \u003cp\u003e11.3 Cells 495\u003c\/p\u003e \u003cp\u003e11.4 Gene Therapy 499\u003c\/p\u003e \u003cp\u003e11.5 Blood Fluid Effect 505\u003c\/p\u003e \u003cp\u003e11.6 Other Application Approaches 507\u003c\/p\u003e \u003cp\u003e12 Conclusion 515\u003c\/p\u003e \u003cp\u003eNomenclature 533\u003c\/p\u003e \u003cp\u003eDNA Entities 545\u003c\/p\u003e \u003cp\u003eVocabulary and Definitions 549\u003c\/p\u003e \u003cp\u003eReferences 564\u003c\/p\u003e \u003cp\u003eIndex\u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Chemistry [\u003ca title=\"See our other books on Chemistry\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Chemistry%20%5BPN%5D%22\"\u003ePN\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Wiley-Scrivener","offers":[{"title":"Brand 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