{"product_id":"discovering-cell-mechanisms-the-creation-of-modern-cell-biology-hardback-9780521812474","title":"Discovering Cell Mechanisms; The Creation of Modern Cell Biology (Hardback) 9780521812474","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eDiscovering Cell Mechanisms\u003c\/font\u003e\u003cbr\u003e\r\n\u003cfont size=\"5\"\u003eThe Creation of Modern Cell Biology\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cem\u003eBechtel emphasises how mechanisms were discovered by cell biologists and the instruments that made these inquiries possible.\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eWilliam Bechtel (Author)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780521812474, Cambridge University Press\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 10 October 2005\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e334 pages\u003cbr\u003e23.5 x 16.3 x 2.7 cm, 0.575 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cem\u003e\u003cfont size=\"3\"\u003e\"Historians will appreciate Bechtel's thorough research in the archives of the Rochefeller Foundation and the American Society for Cell Biology, as well as his use of oral history interviews with some of the principal scientists...Cell biologists especially welcome this new history of their field.\"  \u003cbr\u003e-Lindley Darden, University of Maryland, Journal of the History of Biology\u003c\/font\u003e\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003eBetween 1940 and 1970 pioneers in the new field of cell biology discovered the operative parts of cells and their contributions to cell life. They offered mechanistic accounts that explained cellular phenomena by identifying the relevant parts of cells, the biochemical operations they performed, and the way in which these parts and operations were organised to accomplish important functions. Cell biology was a revolutionary science but in this book it also provides fuel for yet another revolution, one that focuses on the very conception of science itself. Laws have traditionally been regarded as the primary vehicle of explanation, but in the emerging philosophy of science it is mechanisms that do the explanatory work. Bechtel emphasises how mechanisms were discovered, focusing especially on the way in which new instruments made these inquiries possible. He also describes how new journals and societies provided institutional structure to this new enterprise.\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003ePart I. Introduction: Cell Mechanisms and Cell Biology: 1. A different kind of science\u003cbr\u003e 2. The organization of science into disciplines\u003cbr\u003e 3. The new discipline of cell biology\u003cbr\u003e Part II. Explaining Cellular Phenomena through Mechanisms: 4. Historical conceptions of mechanism\u003cbr\u003e 5. Twentieth century conceptions of mechanism\u003cbr\u003e 6. Current conceptions of mechanisms\u003cbr\u003e 7. Representing and reasoning about mechanisms\u003cbr\u003e 8. Levels of organization and reduction\u003cbr\u003e 9. Organization: from Cartesian to biological mechanisms\u003cbr\u003e 10. Discovering and testing models of mechanisms\u003cbr\u003e 11. Conclusions\u003cbr\u003e Part III. The Locus of Cell Mechanisms: Terra Incognita Between Cytology and Biochemistry: 12. Cytological contributions to discovering cell mechanisms up to 1940\u003cbr\u003e 13. Biochemical contributions to discovering cell mechanisms up to 1940\u003cbr\u003e 14. The need to enter the Terra Incognita between cytology and biochemistry\u003cbr\u003e Part IV. Creating New Instruments and Research Techniques to Study Cell Mechanisms: 15. The epistemology of evidence: judging artifacts\u003cbr\u003e 16. The ultracentrifuge and cell fractionation\u003cbr\u003e 17. The electron microscope and electron microscopy\u003cbr\u003e 18. A case study of an artifact charge\u003cbr\u003e 19. Equipped with new instruments and techniques to enter Terra Incognita\u003cbr\u003e Part V. Entering the Terra Incognita Between Biochemistry and Cytology: 20. First steps towards cell biology at the Rockefeller Institute: Claude's introduction of cell fractionation\u003cbr\u003e 21. Robert Bensley: an alternative approach to fractionalism\u003cbr\u003e 22. Competing interpretations of fractions from normal cells\u003cbr\u003e 23. Linking Claude's microsomes to protein synthesis\u003cbr\u003e 24. Adding a biochemical perspective to the Rockefeller Laboratory\u003cbr\u003e 25. Adding electron microscopy as a tool\u003cbr\u003e 26. The state of cell studies at the end of the 1940's\u003cbr\u003e Part VI. New Knowledge: the Mechanisms of the Cytoplasm: 27. The mitochondrion\u003cbr\u003e 28. Microsomes, the endoplasmic reticulum, and ribosomes\u003cbr\u003e 29. Two additional organelles\u003cbr\u003e 30. Giving cell biology an institutional identity.\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Cellular biology [\u003ca title=\"See our other books on Cellular biology\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Cellular%20biology%20%5Bcytology%5D%20%5BPSF%5D%22\"\u003ecytology PSF\u003c\/a\u003e], History of science [\u003ca title=\"See our other books on History of science\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22History%20of%20science%20%5BPDX%5D%22\"\u003ePDX\u003c\/a\u003e], Philosophy of science [\u003ca title=\"See our other books on Philosophy of science\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Philosophy%20of%20science%20%5BPDA%5D%22\"\u003ePDA\u003c\/a\u003e], History of Western philosophy [\u003ca title=\"See our other books on History of Western philosophy\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22History%20of%20Western%20philosophy%20%5BHPC%5D%22\"\u003eHPC\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Cambridge University Press","offers":[{"title":"Default Title","offer_id":46265139167512,"sku":"9780521812474","price":76.65,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/products\/9780521812474i.jpg?v=1692019838","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/discovering-cell-mechanisms-the-creation-of-modern-cell-biology-hardback-9780521812474","provider":"Freshly Printed Books","version":"1.0","type":"link"}