{"product_id":"direct-nose-to-brain-drug-delivery-mechanism-technological-advances-applications-and-regulatory-updates-paperback-9780128225226","title":"Direct Nose-to-Brain Drug Delivery; Mechanism, Technological Advances, Applications, and Regulatory Updates (Paperback) 9780128225226","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eDirect Nose-to-Brain Drug Delivery\u003c\/font\u003e\u003cbr\u003e\r\n\u003cfont size=\"5\"\u003eMechanism, Technological Advances, Applications, and Regulatory Updates\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cem\u003eHighlights the development of novel nanocarrier-based drug delivery systems for targeted drug delivery to the brain\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eChandrakantsing Pardeshi (Edited by), Eliana B. Souto (Edited by)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780128225226, Elsevier Science\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003ePaperback, published 18 June 2021\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e554 pages, 35 illustrations (15 in full color)\u003cbr\u003e23.5 x 19 x 3.4 cm, 1.52 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003e\u003ci\u003eDirect Nose-to-Brain Drug Delivery\u003c\/i\u003e provides the reader with precise knowledge about the strategies and approaches for enhanced nose-to-brain drug delivery. It highlights the development of novel nanocarrier-based drug delivery systems for targeted drug delivery to the brain microenvironments with a focus on the technological advances in the development of the novel drug delivery devices for intranasal administration, including special emphasis on brain targeting through nose. This book explores the various quantification parameters to assess the brain targeting efficiency following intranasal administration and includes an overview on the toxicity aspects of the various materials used to develop the direct nose-to-brain drug delivery vehicles and of the regulatory aspects including patents and current clinical status of the potential neurotherapeutics for the effective management of neuro-ailments. Technological advances in new drug delivery systems with diverse applications in pharmaceutical, biomedical, biomaterials, and biotechnological fields are also explained. This book is a crucial source that will assist the veteran scientists, industrial technologists, and clinical research professionals to develop new drug delivery systems and novel drug administration devices for the treatment of neuro-ailments.\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e\u003cp\u003eSection I Basic considerations in nose-to-brain drug delivery\u003c\/p\u003e \u003cp\u003e1. An overview of anatomical and physiological aspects of the nose and the brain\u003c\/p\u003e \u003cp\u003eDignesh Khunt and Manju Misra\u003c\/p\u003e \u003cp\u003e2. Direct transport theory: From the nose to the brain\u003c\/p\u003e \u003cp\u003eNamdev Dhas, Dattatray Yadav, Ashutosh Singh, Atul Garkal, Ritu Kudarha, Priyanka Bangar, Jignasa Savjani, Chandrakantsing V. Pardeshi, Neha Garg, and Tejal Mehta\u003c\/p\u003e \u003cp\u003e3. Physicochemical, biopharmaceutical, and practical considerations for efficient nose-to-brain drug delivery\u003c\/p\u003e \u003cp\u003eUmesh D. Laddha and Amol A. Tagalpallewar\u003c\/p\u003e\n\u003cb\u003e \u003c\/b\u003e\u003cp\u003eSection II Nanotechnology and naso-brain drug delivery\u003c\/p\u003e \u003cp\u003e4. Nanomedicines for CNS therapy: Fundamental aspects\u003c\/p\u003e \u003cp\u003eDrashti Desai, Bala Prabhakar, and Pravin Shende\u003c\/p\u003e \u003cp\u003e5. Nanotechnological advances in direct nose-to-brain drug delivery for neurodegenerative disorders and other neuroailments \u003c\/p\u003e \u003cp\u003eRahul Shukla, Ashish Kumar, and S.J.S. Flora\u003c\/p\u003e \u003cp\u003e6. Surface modification of nanocarriers as a strategy to enhance the direct nose-to-brain drug delivery \u003c\/p\u003e \u003cp\u003eChandrakantsing V. Pardeshi and Eliana B. Souto\u003c\/p\u003e \u003cp\u003e7. Mucoadhesion as a strategy to enhance the direct nose-to-brain drug delivery\u003c\/p\u003e \u003cp\u003eMrunal Patil\u003c\/p\u003e \u003cp\u003e8. Nanoparticles for direct nose-to-brain drug delivery: Implications of targeting approaches\u003c\/p\u003e \u003cp\u003eRaju O. Sonawane, Yogeshwar Bachhav, Avinash R. Tekade, and Chandrakantsing V. Pardeshi\u003c\/p\u003e \u003cp\u003e9. Strategies for enhanced direct nose-to-brain drug delivery\u003c\/p\u003e \u003cp\u003eYamini Madav and Sarika Wairkar\u003c\/p\u003e\n\u003cb\u003e \u003c\/b\u003e\u003cp\u003eSection III Carriers for direct nose-to-brain drug delivery\u003c\/p\u003e \u003cp\u003e10. Particulate carriers for nose-to-brain delivery\u003c\/p\u003e \u003cp\u003eShiv Bahadur and Kamla Pathak\u003c\/p\u003e \u003cp\u003e11. Vesicular carriers for direct nose-to-brain drug delivery\u003c\/p\u003e \u003cp\u003ePrashant K. Deshmukh, Swapnil N. Jain, Pravin O. Patil, and Chandrakantsing V. Pardeshi\u003c\/p\u003e \u003cp\u003e12. Gel-based delivery of neurotherapeutics via naso-brain pathways\u003c\/p\u003e \u003cp\u003eHitendra S. Mahajan and Payal H. Patil\u003c\/p\u003e\n\u003cb\u003e \u003c\/b\u003e\u003cp\u003eSection IV Applications of direct nose-to-brain delivery\u003c\/p\u003e \u003cp\u003e13. Applications of direct nose-to-brain drug delivery in medicine and pharmacy\u003c\/p\u003e \u003cp\u003eGanesh B. Shevalkar, Mahendra K. Prajapati, Rohan V. Pai, and Kamlesh D. Mali\u003c\/p\u003e \u003cp\u003e14. Applications of direct nose-to-brain drug delivery in biomedicine, biotechnology, tissue engineering, and immunology\u003c\/p\u003e \u003cp\u003eSanjay B. Patil\u003c\/p\u003e \u003cp\u003e15. Diagnostic and theranostic intranasal nanointerventions for brain diseases\u003c\/p\u003e \u003cp\u003ePrashant Upadhaya, Sreeranjini Pulakkat, and Vandana Patravale\u003c\/p\u003e \u003cp\u003e16. Nose-to-brain delivery of biologics and stem cells\u003c\/p\u003e \u003cp\u003eMukta Agrawal, Aditya Narayan Konwar, Amit Alexander, and Vivek Borse\u003c\/p\u003e \u003cp\u003e17. Applications of nose-to-brain delivery in nanodiagnosis and nanotherapy of neurodegenerative disorders\u003c\/p\u003e \u003cp\u003eAbhijeet Kulkarni, Mahesh Shinde, Gaurav Sonawane, Hitesh Raotole, Rohit Pande, and Chandrakantsing V. Pardeshi\u003c\/p\u003e \u003cp\u003e18. Intranasal gene therapy for the treatment of neurological disorders\u003c\/p\u003e \u003cp\u003eNamdev Dhas, Tejal Mehta, Shilpa Sharma, Atul Garkal, Dattatray Yadav, Kartik Hariharan, Babeeta Shamjetshabam, Shubham Khot, Ritu Kudarha, Priyanka Bangar, Gajanan Arbade, and Pratap Kalyankar\u003c\/p\u003e \u003cp\u003e19. Potential of naso-brain drug delivery in glioblastoma therapy\u003c\/p\u003e \u003cp\u003eAmarjitsing Rajput, Nikunj Tandel, Swapnil Borse, and Shital Butani\u003c\/p\u003e \u003cp\u003e20. Nose-to-brain delivery of antiretroviral drugs against NeuroAIDS\u003c\/p\u003e \u003cp\u003eKailas K. Moravkar, Devanshi S. Shah, Durgesh K. Jha, Purnima D. Amin, and Sanjay J. Surana\u003c\/p\u003e\n\u003cb\u003e \u003c\/b\u003e\u003cp\u003eSection V Technological advances for effective drug administration\u003c\/p\u003e \u003cp\u003e21. A technology overview on advanced drug administration devices for effective nose-to-brain delivery\u003c\/p\u003e \u003cp\u003eSadhana R. Shahi and Chandrakantsing V. Pardeshi\u003c\/p\u003e\n\u003cb\u003e \u003c\/b\u003e\u003cp\u003eSection VI Evaluation of direct nose-to-brain drug delivery\u003c\/p\u003e \u003cp\u003e22. Experimental models for evaluation of direct nose-to-brain drug delivery\u003c\/p\u003e \u003cp\u003eVinit V. Agnihotri, Ashish P. Gorle, Chandrakantsing V. Pardeshi, and Sanjay J. Surana\u003c\/p\u003e \u003cp\u003e23. Quantitative and qualitative analysis of direct nose-to-brain drug delivery\u003c\/p\u003e \u003cp\u003eVeena S. Belgamwar, Vidyadevi T. Bhoyar, Sagar Trivedi, and Chandrakantsing V. Pardeshi\u003c\/p\u003e\n\u003cb\u003e \u003c\/b\u003e\u003cp\u003eSection VII Toxicity and regulatory aspects\u003c\/p\u003e \u003cp\u003e24. Toxicity aspects: Crucial obstacles to clinical translation of nanomedicines\u003c\/p\u003e \u003cp\u003eVikas Bansal, Sameer S. Katiyar, and Chander Parkash Dora\u003c\/p\u003e \u003cp\u003e25. Nose-to-brain drug delivery: Regulatory aspects, clinical trials, patents, and future perspectives\u003c\/p\u003e \u003cp\u003eAbhijeet Pandey, Ajinkya Nikam, Shreya Basavraj, Sadhana Mutalik, Divya Gopalan, Sanjay Kulkarni, Bharat Padya, Gasper Fernandes, and Srinivas Mutalik\u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Pharmacology [\u003ca title=\"See our other books on Pharmacology\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Pharmacology%20%5BMMG%5D%22\"\u003eMMG\u003c\/a\u003e], Pharmaceutical industries [\u003ca title=\"See our other books on Pharmaceutical industries\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Pharmaceutical%20industries%20%5BKNDP%5D%22\"\u003eKNDP\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Academic Press","offers":[{"title":"Default Title","offer_id":46648670880024,"sku":"9780128225226","price":135.65,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/products\/9780128225226.jpg?v=1694093221","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/direct-nose-to-brain-drug-delivery-mechanism-technological-advances-applications-and-regulatory-updates-paperback-9780128225226","provider":"Freshly Printed Books","version":"1.0","type":"link"}