{"product_id":"diagnostic-techniques-in-genetics-paperback-softback-9780470870259","title":"Diagnostic Techniques in Genetics (Paperback \/ softback) 9780470870259","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eDiagnostic Techniques in Genetics\u003c\/font\u003e\u003cbr\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003c\/p\u003e\n\u003cp\u003e\u003cfont size=\"4\"\u003eJean-Louis Serre (Edited by), J–L Serre (Author), Isabelle Heath (Translated by), Simon Heath (Translated by)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780470870259, Wiley\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003ePaperback \/ softback, published 25 August 2006\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e270 pages\u003cbr\u003e24.6 x 17 x 1.8 cm, 0.517 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cem\u003e\u003cfont size=\"3\"\u003e\"This is a good, solid, basic review of molecular technology. It is a useful companion book of the beginning scholar in human genetics.\" (\u003ci\u003eDoody's\u003c\/i\u003e, November 2007)\u003c\/font\u003e\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003eEinen breit gefacherten Uberblick uber die Anwendungen von DNA- und RNA-Technologien im Rahmen genetischer Diagnosen biette Ihnen dieser Band. Bewusst vermeidet es der Autor, allzu sehr ins Detail zu gehen; er wendet sich an Studenten unterer Semester, legt deshalb besonderen Wert auf Verstandlichkeit und behandelt vorrangig Themen von allgemeinem Interesse, sodass Sie ein solides Fundament fur weiter gehende Spezialisierungen aufbauen konnen.\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e\u003cp\u003ePreface\u003cbr\u003eList of Contributors\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1. Techniques and Tools in Molecular Biology Used in Genetic Diagnoses\u003cbr\u003e\u003c\/b\u003e1.1 Nucleic acids\u003cbr\u003e1.2 The different types of genetic material studied\u003cbr\u003e1.3 The enzymatic tools for \u003ci\u003ein vitro\u003c\/i\u003e treatment of DNA\u003cbr\u003e1.4 DNA fragmentation and study of the fragments\u003cbr\u003e1.5 Selective amplification of a nucleotide sequence\u003cbr\u003e1.6 DNA fragment ligation: recombinant DNA and cloning\u003cbr\u003e1.7 DNA fragment sequencing\u003cbr\u003e1.8 Modification of the sequence of a DNA fragment: site-directed mutagenesis.\u003cbr\u003e1.9 Molecular hybridization techniques and application\u003cbr\u003e1.10 Other techniques to study allelic diversity\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2. The Diagnosis of Inherited Diseases\u003cbr\u003e\u003c\/b\u003e2.1 Introduction\u003cbr\u003e2.2 Example diagnoses for autosomal diseases\u003cbr\u003e2.3 Example diagnoses for X-linked diseases\u003cbr\u003e2.4 Neurodegenerative diseases\u003cbr\u003e2.5 References and Bibliography.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3. Molecular Diagnosis in Oncology\u003cbr\u003e\u003c\/b\u003e3.1 General introduction\u003cbr\u003e3.2 Cellular pathways targeted by the tumour process\u003cbr\u003e3.3 Types of genetic alteration leading to cancer\u003cbr\u003e3.4 Alteration origins: the role of the repair genes\u003cbr\u003e3.5 Benefits of molecular studies to patient healthcare\u003cbr\u003e3.6 Genetic predisposition to cancers\u003cbr\u003e3.7 Genetic tests for cancer predisposition\u003cbr\u003e3.8 Conclusions and perspectives\u003cbr\u003e3.9 References\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4. Applications of Molecular Biology to Cytogenetics\u003cbr\u003e\u003c\/b\u003e4.1 Introduction\u003cbr\u003e4.2 Molecular diagnosis of anomalies in the number of chromosomes\u003cbr\u003e4.3 Chromosomal microdeletions\u003cbr\u003e4.4 Uniparental disomies\u003cbr\u003e4.5 Conclusions and perspectives\u003cbr\u003e4.6 References\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5. Screening and Identification of Pathogenic and Exogenic Agents.\u003cbr\u003e\u003c\/b\u003e5.1 Clinical virology\u003cbr\u003e5.2 Clinical bacteriology\u003cbr\u003e5.3 Detection of GMOs\u003cbr\u003e5.4 References and Bibliography\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6. Identification Using Genetic Fingerprints\u003cbr\u003e\u003c\/b\u003e6.1 Introduction\u003cbr\u003e6.2 Genetic fingerprints by the analysis of nuclear DNA\u003cbr\u003e6.2.4 A special case: the Y chromosome sequence\u003cbr\u003e6.3 Genetic fingerprints with mitochondrial DNA\u003cbr\u003e6.4 Society facing the question of genetic fingerprint files.\u003cbr\u003e6.5 Conclusion\u003cbr\u003e6.6 Bibliography\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7. Molecular Genetics and Populations\u003cbr\u003e\u003c\/b\u003e7.1 Hardy–Weinberg equilibrium and measures of genetic diversity\u003cbr\u003e7.4 Diagnosis with genetic testing: cystic fibrosis – an academic case\u003cbr\u003e7.5 Gametic disequilibrium\u003cbr\u003e7.6 Reference and Bibliography\u003c\/p\u003e \u003cp\u003e\u003cb\u003eIndex\u003c\/b\u003e\u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Biology, life sciences [\u003ca title=\"See our other books on Biology, life sciences\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Biology,%20life%20sciences%20%5BPS%5D%22\"\u003ePS\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Wiley","offers":[{"title":"Brand New","offer_id":52278057468184,"sku":"9780470870259","price":53.66,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/files\/9780470870259.jpg?v=1781457774","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/diagnostic-techniques-in-genetics-paperback-softback-9780470870259","provider":"Freshly Printed Books","version":"1.0","type":"link"}