{"product_id":"developmental-origins-of-health-and-disease-hardback-9781009272247","title":"Developmental Origins of Health and Disease (Hardback) 9781009272247","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eDevelopmental Origins of Health and Disease\u003c\/font\u003e\u003cbr\u003e\r\n\r\n\r\n\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFully revised new edition highlighting the scientific and clinical advances in the field of developmental origins of health and disease.\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eLucilla Poston (Edited by), Keith M. Godfrey (Edited by), Peter D. Gluckman (Edited by), Mark A. Hanson (Edited by)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9781009272247, Cambridge University Press\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 22 December 2022\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e320 pages\u003cbr\u003e26.1 x 18.3 x 1.6 cm, 0.65 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003eThe concept of the early life developmental origins of health and disease (DOHaD) in adults has stimulated a new approach to understanding disease trajectories, with major public health implications. Indeed, the principle of the 'lifecourse of disease' now influences health policies internationally. Environmental influences during pregnancy and early life that affect lifelong health are well documented, but there is a new focus on the preconception period and the significance of paternal health on the fetus. This fully revised second edition highlights scientific and clinical advances in the field, exploring new understanding of mechanisms such as epigenetics and the increasingly recognised role of external influences, including pollution. The book is structured logically, covering environment, clinical outcomes, mechanisms of DOHaD, interventions throughout the lifespan and finally implications for public health and policy. Clinicians and scientists alike will improve their understanding of the developmental origins of health and disease with this essential text.\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSection I. Overview: 1. Overview and introduction to the 2nd edition of the developmental origins of health and disease (DOHaD) Lucilla Poston, Keith M. Godfrey, Sir Peter D. Gluckman and Mark A. Hanson\u003cbr\u003e Section II. Exposures driving long-term DOHaD effects: 2. The evolutionary basis of DOHaD Felicia M Low, Peter D Gluckman and Mark A Hanson\u003cbr\u003e 3. Timing: Critical DOHaD windows with lifelong effects Keith M. Godfrey, Tom Fleming, Mary Barker, Judith Stephenson, Mark Vickers, Frank Bloomfield and Rachael Taylor\u003cbr\u003e 4. Long-term effects of food insecurity and undernutrition in early life Sophie E. Moore\u003cbr\u003e 5. Short and long-term effects of maternal obesity and dysglycaemia for women and their children Jodie M. Dodd, Amanda J Poprzeczny, Andrea R. Duessen and Jennie Louise\u003cbr\u003e 6. Long-term DOHaD effects of prenatal maternal stress and mental health Matthias Schwab and Florian Rakers\u003cbr\u003e 7. Environmental exposures in early life: effects of air pollution, chemicals and climate change on human health and wellbeing Kirsten R. Poore, Marie Pedersen and Sibylle Ermler\u003cbr\u003e 8. Developmental programming and the microbiome: How the maternal environment and early life shapes the infant gut microbiome pathway(s) and risk of disease Kameron Y. Sugino and Jacob E. Friedman\u003cbr\u003e 9. Exposures driving long-term effects of DOHaD effects: Influence of assisted reproductive technologies Daniel R. Brison, John C. M. Dumoulin, Hannah L. Morgan, Tessa J. Roseboom and Adam J. Watkins\u003cbr\u003e Section III. Outcomes: 10. Cardiometabolic and renal DOHaD outcomes in offspring of complicated pregnancy Dino A. Giussani, Rebecca M. Reynolds, Paul Leeson, Karen M. Moritz, John F. Bertram and Susan E. Ozanne\u003cbr\u003e 11. Development origins of chronic respiratory diseases Liesbeth Duijts, Annemiek Mian, Tarik Karramass and Vincent W. V. Jaddoe\u003cbr\u003e 12. Early life adversity and female reproductive outcomes: How growth, diet and nutrition impact reproductive function and accelerated reproductive ageing Patrycja A. Jazwiec and Deborah M. Sloboda\u003cbr\u003e 13. Developmental programming of ageing induced by poor maternal nutrition\u003cbr\u003e evidence from rodent studies Elena Zambrano and Peter W. Nathanielsz\u003cbr\u003e Section IV. Mechanisms: 14. Visualizing structural underpinnings of DOHaD Kent L. Thornburg, John Bertram, Jacob E. Friedman, David Hill, Kevin Kolahi and Christopher Kroenke\u003cbr\u003e 15. Molecular and epigenetic mechanisms of DOHaD Richard Saffery, Amanda Vlahos and Toby Mansell\u003cbr\u003e 16. The role of the placenta in DOHaD Rohan M. Lewis and Amanda N. Sferruzzi-Perri\u003cbr\u003e Section V. Interventions: 17. Interventions to prevent DOHaD effects in pregnancy Lucilla Poston\u003cbr\u003e 18. Interventions to prevent DOHaD effects in infancy and early childhood Bart?omiej Mateusz Zalewski, Bernadeta Patro-Go??b, Barbara Bo?ek, M. Ko?odziej, Kathryn V. Dalrymple, Lucilla Poston and Hania Szajewska\u003cbr\u003e Section VI. Public health and policy implications of interventions\u003cbr\u003e 19. Education and science communication: Translation of DOHaD evidence for health benefit Jacquie L. Bay and Suzanne Trask\u003cbr\u003e 20. DOHaD – engaging with new global issues to inform policy Peter D. Gluckman and Mark A. Hanson.\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Paediatric nursing [\u003ca title=\"See our other books on Paediatric nursing\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Paediatric%20nursing%20%5BMQCL3%5D%22\"\u003eMQCL3\u003c\/a\u003e], Paediatric medicine [\u003ca title=\"See our other books on Paediatric medicine\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Paediatric%20medicine%20%5BMJW%5D%22\"\u003eMJW\u003c\/a\u003e], Materno-fetal medicine [\u003ca title=\"See our other books on Materno-fetal medicine\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Materno-fetal%20medicine%20%5BMJTF%5D%22\"\u003eMJTF\u003c\/a\u003e], Reproductive medicine [\u003ca title=\"See our other books on Reproductive medicine\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Reproductive%20medicine%20%5BMFKC%5D%22\"\u003eMFKC\u003c\/a\u003e], Public health \u0026amp; preventive medicine [\u003ca title=\"See our other books on Public health \u0026amp; preventive medicine\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Public%20health%20\u0026amp;%20preventive%20medicine%20%5BMBN%5D%22\"\u003eMBN\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Cambridge University Press","offers":[{"title":"Default Title","offer_id":46003052085528,"sku":"9781009272247","price":62.89,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/products\/9781009272247i.jpg?v=1696791734","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/developmental-origins-of-health-and-disease-hardback-9781009272247","provider":"Freshly Printed Books","version":"1.0","type":"link"}