{"product_id":"deep-learning-for-targeted-treatments-transformation-in-healthcare-hardback-9781119857327","title":"Deep Learning for Targeted Treatments; Transformation in Healthcare (Hardback) 9781119857327","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eDeep Learning for Targeted Treatments\u003c\/font\u003e\u003cbr\u003e\r\n\u003cfont size=\"5\"\u003eTransformation in Healthcare\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eRishabha Malviya (Edited by), R Malviya (Author), Gheorghita Ghinea (Edited by), Rajesh Kumar Dhanaraj (Edited by), Balamurugan Balusamy (Edited by), Sonali Sundram (Edited by)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9781119857327, Wiley\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 28 September 2022\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e464 pages\u003cbr\u003e25 x 15 x 1.5 cm, 0.93 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003e\u003cb\u003eDEEP LEARNING FOR TREATMENTS\u003c\/b\u003e \u003cp\u003e\u003cb\u003eThe book provides the direction for future research in deep learning in terms of its role in targeted treatment, biological systems, site-specific drug delivery, risk assessment in therapy, etc.\u003c\/b\u003e \u003c\/p\u003e\n\u003cp\u003e\u003ci\u003eDeep Learning for Targeted Treatments\u003c\/i\u003e describes the importance of the deep learning framework for patient care, disease imaging\/detection, and health management. Since deep learning can and does play a major role in a patient’s healthcare management by controlling drug delivery to targeted tissues or organs, the main focus of the book is to leverage the various prospects of the DL framework for targeted therapy of various diseases. In terms of its industrial significance, this general-purpose automatic learning procedure is being widely implemented in pharmaceutical healthcare.  \u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eAudience\u003c\/b\u003e\u003cbr\u003e The book will be immensely interesting and useful to researchers and those working in the areas of clinical research, disease management, pharmaceuticals, R\u0026amp;D formulation, deep learning analytics, remote healthcare management, healthcare analytics, and deep learning in the healthcare industry.\u003c\/p\u003e\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e\u003cp\u003ePreface xvii\u003c\/p\u003e \u003cp\u003eAcknowledgement xix\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 Deep Learning and Site-Specific Drug Delivery: The Future and Intelligent Decision Support for Pharmaceutical Manufacturing Science 1\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eDhanalekshmi Unnikrishnan Meenakshi, Selvasudha Nandakumar, Arul Prakash Francis, Pushpa Sweety, Shivkanya Fuloria, Neeraj Kumar Fuloria, Vetriselvan Subramaniyan and Shah Alam Khan\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e1.1 Introduction 2\u003c\/p\u003e \u003cp\u003e1.2 Drug Discovery, Screening and Repurposing 5\u003c\/p\u003e \u003cp\u003e1.3 DL and Pharmaceutical Formulation Strategy 11\u003c\/p\u003e \u003cp\u003e1.3.1 DL in Dose and Formulation Prediction 11\u003c\/p\u003e \u003cp\u003e1.3.2 DL in Dissolution and Release Studies 15\u003c\/p\u003e \u003cp\u003e1.3.3 DL in the Manufacturing Process 16\u003c\/p\u003e \u003cp\u003e1.4 Deep Learning Models for Nanoparticle-Based Drug Delivery 19\u003c\/p\u003e \u003cp\u003e1.4.1 Nanoparticles With High Drug Delivery Capacities Using Perturbation Theory 20\u003c\/p\u003e \u003cp\u003e1.4.2 Artificial Intelligence and Drug Delivery Algorithms 21\u003c\/p\u003e \u003cp\u003e1.4.3 Nanoinformatics 22\u003c\/p\u003e \u003cp\u003e1.5 Model Prediction for Site-Specific Drug Delivery 23\u003c\/p\u003e \u003cp\u003e1.5.1 Prediction of Mode and a Site-Specific Action 23\u003c\/p\u003e \u003cp\u003e1.5.2 Precision Medicine 26\u003c\/p\u003e \u003cp\u003e1.6 Future Scope and Challenges 27\u003c\/p\u003e \u003cp\u003e1.7 Conclusion 29\u003c\/p\u003e \u003cp\u003eReferences 30\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 Role of Deep Learning, Blockchain and Internet of Things in Patient Care 39\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eAkanksha Sharma, Rishabha Malviya and Sonali Sundram\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2.1 Introduction 40\u003c\/p\u003e \u003cp\u003e2.2 IoT and WBAN in Healthcare Systems 42\u003c\/p\u003e \u003cp\u003e2.2.1 IoT in Healthcare 42\u003c\/p\u003e \u003cp\u003e2.2.2 WBAN 44\u003c\/p\u003e \u003cp\u003e2.2.2.1 Key Features of Medical Networks in the Wireless Body Area 44\u003c\/p\u003e \u003cp\u003e2.2.2.2 Data Transmission \u0026amp; Storage Health 45\u003c\/p\u003e \u003cp\u003e2.2.2.3 Privacy and Security Concerns in Big Data 45\u003c\/p\u003e \u003cp\u003e2.3 Blockchain Technology in Healthcare 46\u003c\/p\u003e \u003cp\u003e2.3.1 Importance of Blockchain 46\u003c\/p\u003e \u003cp\u003e2.3.2 Role of Blockchain in Healthcare 47\u003c\/p\u003e \u003cp\u003e2.3.3 Benefits of Blockchain in Healthcare Applications 48\u003c\/p\u003e \u003cp\u003e2.3.4 Elements of Blockchain 49\u003c\/p\u003e \u003cp\u003e2.3.5 Situation Awareness and Healthcare Decision Support with Combined Machine Learning and Semantic Modeling 51\u003c\/p\u003e \u003cp\u003e2.3.6 Mobile Health and Remote Monitoring 53\u003c\/p\u003e \u003cp\u003e2.3.7 Different Mobile Health Application with Description of Usage in Area of Application 54\u003c\/p\u003e \u003cp\u003e2.3.8 Patient-Centered Blockchain Mode 55\u003c\/p\u003e \u003cp\u003e2.3.9 Electronic Medical Record 57\u003c\/p\u003e \u003cp\u003e2.3.9.1 The Most Significant Barriers to Adoption Are 60\u003c\/p\u003e \u003cp\u003e2.3.9.2 Concern Regarding Negative Unintended Consequences of Technology 60\u003c\/p\u003e \u003cp\u003e2.4 Deep Learning in Healthcare 62\u003c\/p\u003e \u003cp\u003e2.4.1 Deep Learning Models 63\u003c\/p\u003e \u003cp\u003e2.4.1.1 Recurrent Neural Networks (RNN) 63\u003c\/p\u003e \u003cp\u003e2.4.1.2 Convolutional Neural Networks (CNN) 64\u003c\/p\u003e \u003cp\u003e2.4.1.3 Deep Belief Network (DBN) 65\u003c\/p\u003e \u003cp\u003e2.4.1.4 Contrasts Between Models 66\u003c\/p\u003e \u003cp\u003e2.4.1.5 Use of Deep Learning in Healthcare 66\u003c\/p\u003e \u003cp\u003e2.5 Conclusion 70\u003c\/p\u003e \u003cp\u003e2.6 Acknowledgments 70\u003c\/p\u003e \u003cp\u003eReferences 70\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Deep Learning on Site-Specific Drug Delivery System 77\u003cbr\u003e \u003c\/b\u003e\u003ci\u003ePrem Shankar Mishra, Rakhi Mishra and Rupa Mazumder\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3.1 Introduction 78\u003c\/p\u003e \u003cp\u003e3.2 Deep Learning 81\u003c\/p\u003e \u003cp\u003e3.2.1 Types of Algorithms Used in Deep Learning 81\u003c\/p\u003e \u003cp\u003e3.2.1.1 Convolutional Neural Networks (CNNs) 82\u003c\/p\u003e \u003cp\u003e3.2.1.2 Long Short-Term Memory Networks (LSTMs) 83\u003c\/p\u003e \u003cp\u003e3.2.1.3 Recurrent Neural Networks 83\u003c\/p\u003e \u003cp\u003e3.2.1.4 Generative Adversarial Networks (GANs) 84\u003c\/p\u003e \u003cp\u003e3.2.1.5 Radial Basis Function Networks 84\u003c\/p\u003e \u003cp\u003e3.2.1.6 Multilayer Perceptron 85\u003c\/p\u003e \u003cp\u003e3.2.1.7 Self-Organizing Maps 85\u003c\/p\u003e \u003cp\u003e3.2.1.8 Deep Belief Networks 85\u003c\/p\u003e \u003cp\u003e3.3 Machine Learning and Deep Learning Comparison 86\u003c\/p\u003e \u003cp\u003e3.4 Applications of Deep Learning in Drug Delivery System 87\u003c\/p\u003e \u003cp\u003e3.5 Conclusion 90\u003c\/p\u003e \u003cp\u003eReferences 90\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Deep Learning Advancements in Target Delivery 101\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eSudhanshu Mishra, Palak Gupta, Smriti Ojha, Vijay Sharma, Vicky Anthony and Disha Sharma\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4.1 Introduction: Deep Learning and Targeted Drug Delivery 102\u003c\/p\u003e \u003cp\u003e4.2 Different Models\/Approaches of Deep Learning and Targeting Drug 104\u003c\/p\u003e \u003cp\u003e4.3 QSAR Model 105\u003c\/p\u003e \u003cp\u003e4.3.1 Model of Deep Long-Term Short-Term Memory 105\u003c\/p\u003e \u003cp\u003e4.3.2 RNN Model 107\u003c\/p\u003e \u003cp\u003e4.3.3 CNN Model 108\u003c\/p\u003e \u003cp\u003e4.4 Deep Learning Process Applications in Pharmaceutical 109\u003c\/p\u003e \u003cp\u003e4.5 Techniques for Predicting Pharmacotherapy 109\u003c\/p\u003e \u003cp\u003e4.6 Approach to Diagnosis 110\u003c\/p\u003e \u003cp\u003e4.7 Application 113\u003c\/p\u003e \u003cp\u003e4.7.1 Deep Learning in Drug Discovery 114\u003c\/p\u003e \u003cp\u003e4.7.2 Medical Imaging and Deep Learning Process 115\u003c\/p\u003e \u003cp\u003e4.7.3 Deep Learning in Diagnostic and Screening 116\u003c\/p\u003e \u003cp\u003e4.7.4 Clinical Trials Using Deep Learning Models 116\u003c\/p\u003e \u003cp\u003e4.7.5 Learning for Personalized Medicine 117\u003c\/p\u003e \u003cp\u003e4.8 Conclusion 121\u003c\/p\u003e \u003cp\u003eAcknowledgment 122\u003c\/p\u003e \u003cp\u003eReferences 122\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Deep Learning and Precision Medicine: Lessons to Learn for the Preeminent Treatment for Malignant Tumors 127\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eSelvasudha Nandakumar, Shah Alam Khan, Poovi Ganesan, Pushpa Sweety, Arul Prakash Francis, Mahendran Sekar, Rukkumani Rajagopalan and Dhanalekshmi Unnikrishnan Meenakshi\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5.1 Introduction 128\u003c\/p\u003e \u003cp\u003e5.2 Role of DL in Gene Identification, Unique Genomic Analysis, and Precise Cancer Diagnosis 132\u003c\/p\u003e \u003cp\u003e5.2.1 Gene Identification and Genome Data 133\u003c\/p\u003e \u003cp\u003e5.2.2 Image Diagnosis 135\u003c\/p\u003e \u003cp\u003e5.2.3 Radiomics, Radiogenomics, and Digital Biopsy 137\u003c\/p\u003e \u003cp\u003e5.2.4 Medical Image Analysis in Mammography 138\u003c\/p\u003e \u003cp\u003e5.2.5 Magnetic Resonance Imaging 139\u003c\/p\u003e \u003cp\u003e5.2.6 CT Imaging 140\u003c\/p\u003e \u003cp\u003e5.3 dl in Next-Generation Sequencing, Biomarkers, and Clinical Validation 141\u003c\/p\u003e \u003cp\u003e5.3.1 Next-Generation Sequencing 141\u003c\/p\u003e \u003cp\u003e5.3.2 Biomarkers and Clinical Validation 142\u003c\/p\u003e \u003cp\u003e5.4 dl and Translational Oncology 144\u003c\/p\u003e \u003cp\u003e5.4.1 Prediction 144\u003c\/p\u003e \u003cp\u003e5.4.2 Segmentation 146\u003c\/p\u003e \u003cp\u003e5.4.3 Knowledge Graphs and Cancer Drug Repurposing 147\u003c\/p\u003e \u003cp\u003e5.4.4 Automated Treatment Planning 149\u003c\/p\u003e \u003cp\u003e5.4.5 Clinical Benefits 150\u003c\/p\u003e \u003cp\u003e5.5 DL in Clinical Trials—A Necessary Paradigm Shift 152\u003c\/p\u003e \u003cp\u003e5.6 Challenges and Limitations 155\u003c\/p\u003e \u003cp\u003e5.7 Conclusion 157\u003c\/p\u003e \u003cp\u003eReferences 157\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 Personalized Therapy Using Deep Learning Advances 171\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eNishant Gaur, Rashmi Dharwadkar and Jinsu Thomas\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6.1 Introduction 172\u003c\/p\u003e \u003cp\u003e6.2 Deep Learning 174\u003c\/p\u003e \u003cp\u003e6.2.1 Convolutional Neural Networks 175\u003c\/p\u003e \u003cp\u003e6.2.2 Autoencoders 180\u003c\/p\u003e \u003cp\u003e6.2.3 Deep Belief Network (DBN) 182\u003c\/p\u003e \u003cp\u003e6.2.4 Deep Reinforcement Learning 184\u003c\/p\u003e \u003cp\u003e6.2.5 Generative Adversarial Network 186\u003c\/p\u003e \u003cp\u003e6.2.6 Long Short-Term Memory Networks 188\u003c\/p\u003e \u003cp\u003eReferences 191\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 Tele-Health Monitoring Using Artificial Intelligence Deep Learning Framework 199\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eSwati Verma, Rishabha Malviya, Md Aftab Alam and Bhuneshwar Dutta Tripathi\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7.1 Introduction 200\u003c\/p\u003e \u003cp\u003e7.2 Artificial Intelligence 200\u003c\/p\u003e \u003cp\u003e7.2.1 Types of Artificial Intelligence 201\u003c\/p\u003e \u003cp\u003e7.2.1.1 Machine Intelligence 201\u003c\/p\u003e \u003cp\u003e7.2.1.2 Types of Machine Intelligence 203\u003c\/p\u003e \u003cp\u003e7.2.2 Applications of Artificial Intelligence 204\u003c\/p\u003e \u003cp\u003e7.2.2.1 Role in Healthcare Diagnostics 205\u003c\/p\u003e \u003cp\u003e7.2.2.2 AI in Telehealth 205\u003c\/p\u003e \u003cp\u003e7.2.2.3 Role in Structural Health Monitoring 205\u003c\/p\u003e \u003cp\u003e7.2.2.4 Role in Remote Medicare Management 206\u003c\/p\u003e \u003cp\u003e7.2.2.5 Predictive Analysis Using Big Data 207\u003c\/p\u003e \u003cp\u003e7.2.2.6 AI’s Role in Virtual Monitoring of Patients 208\u003c\/p\u003e \u003cp\u003e7.2.2.7 Functions of Devices 208\u003c\/p\u003e \u003cp\u003e7.2.2.8 Clinical Outcomes Through Remote Patient Monitoring 210\u003c\/p\u003e \u003cp\u003e7.2.2.9 Clinical Decision Support 211\u003c\/p\u003e \u003cp\u003e7.2.3 Utilization of Artificial Intelligence in Telemedicine 211\u003c\/p\u003e \u003cp\u003e7.2.3.1 Artificial Intelligence–Assisted Telemedicine 212\u003c\/p\u003e \u003cp\u003e7.2.3.2 Telehealth and New Care Models 213\u003c\/p\u003e \u003cp\u003e7.2.3.3 Strategy of Telecare Domain 214\u003c\/p\u003e \u003cp\u003e7.2.3.4 Role of AI-Assisted Telemedicine in Various Domains 216\u003c\/p\u003e \u003cp\u003e7.3 AI-Enabled Telehealth: Social and Ethical Considerations 218\u003c\/p\u003e \u003cp\u003e7.4 Conclusion 219\u003c\/p\u003e \u003cp\u003eReferences 220\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 Deep Learning Framework for Cancer Diagnosis and Treatment 229\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eShiv Bahadur and Prashant Kumar\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8.1 Deep Learning: An Emerging Field for Cancer Management 230\u003c\/p\u003e \u003cp\u003e8.2 Deep Learning Framework in Diagnosis and Treatment of Cancer 232\u003c\/p\u003e \u003cp\u003e8.3 Applications of Deep Learning in Cancer Diagnosis 233\u003c\/p\u003e \u003cp\u003e8.3.1 Medical Imaging Through Artificial Intelligence 234\u003c\/p\u003e \u003cp\u003e8.3.2 Biomarkers Identification in the Diagnosis of Cancer Through Deep Learning 234\u003c\/p\u003e \u003cp\u003e8.3.3 Digital Pathology Through Deep Learning 235\u003c\/p\u003e \u003cp\u003e8.3.4 Application of Artificial Intelligence in Surgery 236\u003c\/p\u003e \u003cp\u003e8.3.5 Histopathological Images Using Deep Learning 237\u003c\/p\u003e \u003cp\u003e8.3.6 MRI and Ultrasound Images Through Deep Learning 237\u003c\/p\u003e \u003cp\u003e8.4 Clinical Applications of Deep Learning in the Management of Cancer 238\u003c\/p\u003e \u003cp\u003e8.5 Ethical Considerations in Deep Learning–Based Robotic Therapy 239\u003c\/p\u003e \u003cp\u003e8.6 Conclusion 240\u003c\/p\u003e \u003cp\u003eAcknowledgments 240\u003c\/p\u003e \u003cp\u003eReferences 241\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 Applications of Deep Learning in Radiation Therapy 247\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eAkanksha Sharma, Ashish Verma, Rishabha Malviya and Shalini Yadav\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9.1 Introduction 248\u003c\/p\u003e \u003cp\u003e9.2 History of Radiotherapy 250\u003c\/p\u003e \u003cp\u003e9.3 Principal of Radiotherapy 251\u003c\/p\u003e \u003cp\u003e9.4 Deep Learning 251\u003c\/p\u003e \u003cp\u003e9.5 Radiation Therapy Techniques 254\u003c\/p\u003e \u003cp\u003e9.5.1 External Beam Radiation Therapy 257\u003c\/p\u003e \u003cp\u003e9.5.2 Three-Dimensional Conformal Radiation Therapy (3D-CRT) 259\u003c\/p\u003e \u003cp\u003e9.5.3 Intensity Modulated Radiation Therapy (IMRT) 260\u003c\/p\u003e \u003cp\u003e9.5.4 Image-Guided Radiation Therapy (IGRT) 261\u003c\/p\u003e \u003cp\u003e9.5.5 Intraoperative Radiation Therapy (IORT) 263\u003c\/p\u003e \u003cp\u003e9.5.6 Brachytherapy 265\u003c\/p\u003e \u003cp\u003e9.5.7 Stereotactic Radiosurgery (SRS) 268\u003c\/p\u003e \u003cp\u003e9.6 Different Role of Deep Learning with Corresponding Role of Medical Physicist 269\u003c\/p\u003e \u003cp\u003e9.6.1 Deep Learning in Patient Assessment 269\u003c\/p\u003e \u003cp\u003e9.6.1.1 Radiotherapy Results Prediction 269\u003c\/p\u003e \u003cp\u003e9.6.1.2 Respiratory Signal Prediction 271\u003c\/p\u003e \u003cp\u003e9.6.2 Simulation Computed Tomography 271\u003c\/p\u003e \u003cp\u003e9.6.3 Targets and Organs-at-Risk Segmentation 273\u003c\/p\u003e \u003cp\u003e9.6.4 Treatment Planning 274\u003c\/p\u003e \u003cp\u003e9.6.4.1 Beam Angle Optimization 274\u003c\/p\u003e \u003cp\u003e9.6.4.2 Dose Prediction 276\u003c\/p\u003e \u003cp\u003e9.6.5 Other Role of Deep Learning in Corresponds with Medical Physicists 277\u003c\/p\u003e \u003cp\u003e9.7 Conclusion 280\u003c\/p\u003e \u003cp\u003eReferences 281\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 Application of Deep Learning in Radiation Therapy 289\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eShilpa Rawat, Shilpa Singh, Md. Aftab Alam and Rishabha Malviya\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10.1 Introduction 290\u003c\/p\u003e \u003cp\u003e10.2 Radiotherapy 291\u003c\/p\u003e \u003cp\u003e10.3 Principle of Deep Learning and Machine Learning 293\u003c\/p\u003e \u003cp\u003e10.3.1 Deep Neural Networks (DNN) 294\u003c\/p\u003e \u003cp\u003e10.3.2 Convolutional Neural Network 295\u003c\/p\u003e \u003cp\u003e10.4 Role of AI and Deep Learning in Radiation Therapy 295\u003c\/p\u003e \u003cp\u003e10.5 Platforms for Deep Learning and Tools for Radiotherapy 297\u003c\/p\u003e \u003cp\u003e10.6 Radiation Therapy Implementation in Deep Learning 300\u003c\/p\u003e \u003cp\u003e10.6.1 Deep Learning and Imaging Techniques 301\u003c\/p\u003e \u003cp\u003e10.6.2 Image Segmentation 301\u003c\/p\u003e \u003cp\u003e10.6.3 Lesion Segmentation 302\u003c\/p\u003e \u003cp\u003e10.6.4 Computer-Aided Diagnosis 302\u003c\/p\u003e \u003cp\u003e10.6.5 Computer-Aided Detection 303\u003c\/p\u003e \u003cp\u003e10.6.6 Quality Assurance 304\u003c\/p\u003e \u003cp\u003e10.6.7 Treatment Planning 305\u003c\/p\u003e \u003cp\u003e10.6.8 Treatment Delivery 305\u003c\/p\u003e \u003cp\u003e10.6.9 Response to Treatment 306\u003c\/p\u003e \u003cp\u003e10.7 Prediction of Outcomes 307\u003c\/p\u003e \u003cp\u003e10.7.1 Toxicity 309\u003c\/p\u003e \u003cp\u003e10.7.2 Survival and the Ability to Respond 310\u003c\/p\u003e \u003cp\u003e10.8 Deep Learning in Conjunction With Radiomoic 312\u003c\/p\u003e \u003cp\u003e10.9 Planning for Treatment 314\u003c\/p\u003e \u003cp\u003e10.9.1 Optimization of Beam Angle 315\u003c\/p\u003e \u003cp\u003e10.9.2 Prediction of Dose 315\u003c\/p\u003e \u003cp\u003e10.10 Deep Learning’s Challenges and Future Potential 316\u003c\/p\u003e \u003cp\u003e10.11 Conclusion 317\u003c\/p\u003e \u003cp\u003eReferences 318\u003c\/p\u003e \u003cp\u003e\u003cb\u003e11 Deep Learning Framework for Cancer 333\u003cbr\u003e \u003c\/b\u003e\u003ci\u003ePratishtha\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e11.1 Introduction 334\u003c\/p\u003e \u003cp\u003e11.2 Brief History of Deep Learning 335\u003c\/p\u003e \u003cp\u003e11.3 Types of Deep Learning Methods 336\u003c\/p\u003e \u003cp\u003e11.4 Applications of Deep Learning 339\u003c\/p\u003e \u003cp\u003e11.4.1 Toxicity Detection for Different Chemical Structures 339\u003c\/p\u003e \u003cp\u003e11.4.2 Mitosis Detection 340\u003c\/p\u003e \u003cp\u003e11.4.3 Radiology or Medical Imaging 341\u003c\/p\u003e \u003cp\u003e11.4.4 Hallucination 342\u003c\/p\u003e \u003cp\u003e11.4.5 Next-Generation Sequencing (NGS) 342\u003c\/p\u003e \u003cp\u003e11.4.6 Drug Discovery 343\u003c\/p\u003e \u003cp\u003e11.4.7 Sequence or Video Generation 343\u003c\/p\u003e \u003cp\u003e11.4.8 Other Applications 343\u003c\/p\u003e \u003cp\u003e11.5 Cancer 343\u003c\/p\u003e \u003cp\u003e11.5.1 Factors 344\u003c\/p\u003e \u003cp\u003e11.5.1.1 Heredity 345\u003c\/p\u003e \u003cp\u003e11.5.1.2 Ionizing Radiation 345\u003c\/p\u003e \u003cp\u003e11.5.1.3 Chemical Substances 345\u003c\/p\u003e \u003cp\u003e11.5.1.4 Dietary Factors 345\u003c\/p\u003e \u003cp\u003e11.5.1.5 Estrogen 346\u003c\/p\u003e \u003cp\u003e11.5.1.6 Viruses 346\u003c\/p\u003e \u003cp\u003e11.5.1.7 Stress 347\u003c\/p\u003e \u003cp\u003e11.5.1.8 Age 347\u003c\/p\u003e \u003cp\u003e11.5.2 Signs and Symptoms of Cancer 347\u003c\/p\u003e \u003cp\u003e11.5.3 Types of Cancer Treatment Available 348\u003c\/p\u003e \u003cp\u003e11.5.3.1 Surgery 348\u003c\/p\u003e \u003cp\u003e11.5.3.2 Radiation Therapy 348\u003c\/p\u003e \u003cp\u003e11.5.3.3 Chemotherapy 348\u003c\/p\u003e \u003cp\u003e11.5.3.4 Immunotherapy 348\u003c\/p\u003e \u003cp\u003e11.5.3.5 Targeted Therapy 349\u003c\/p\u003e \u003cp\u003e11.5.3.6 Hormone Therapy 349\u003c\/p\u003e \u003cp\u003e11.5.3.7 Stem Cell Transplant 349\u003c\/p\u003e \u003cp\u003e11.5.3.8 Precision Medicine 349\u003c\/p\u003e \u003cp\u003e11.5.4 Types of Cancer 349\u003c\/p\u003e \u003cp\u003e11.5.4.1 Carcinoma 349\u003c\/p\u003e \u003cp\u003e11.5.4.2 Sarcoma 349\u003c\/p\u003e \u003cp\u003e11.5.4.3 Leukemia 350\u003c\/p\u003e \u003cp\u003e11.5.4.4 Lymphoma and Myeloma 350\u003c\/p\u003e \u003cp\u003e11.5.4.5 Central Nervous System (CNS) Cancers 350\u003c\/p\u003e \u003cp\u003e11.5.5 The Development of Cancer (Pathogenesis) Cancer 350\u003c\/p\u003e \u003cp\u003e11.6 Role of Deep Learning in Various Types of Cancer 350\u003c\/p\u003e \u003cp\u003e11.6.1 Skin Cancer 351\u003c\/p\u003e \u003cp\u003e11.6.1.1 Common Symptoms of Melanoma 351\u003c\/p\u003e \u003cp\u003e11.6.1.2 Types of Skin Cancer 352\u003c\/p\u003e \u003cp\u003e11.6.1.3 Prevention 353\u003c\/p\u003e \u003cp\u003e11.6.1.4 Treatment 353\u003c\/p\u003e \u003cp\u003e11.6.2 Deep Learning in Skin Cancer 354\u003c\/p\u003e \u003cp\u003e11.6.3 Pancreatic Cancer 354\u003c\/p\u003e \u003cp\u003e11.6.3.1 Symptoms of Pancreatic Cancer 355\u003c\/p\u003e \u003cp\u003e11.6.3.2 Causes or Risk Factors of Pancreatic Cancer 355\u003c\/p\u003e \u003cp\u003e11.6.3.3 Treatments of Pancreatic Cancer 355\u003c\/p\u003e \u003cp\u003e11.6.4 Deep Learning in Pancreatic Cancer 355\u003c\/p\u003e \u003cp\u003e11.6.5 Tobacco-Driven Lung Cancer 357\u003c\/p\u003e \u003cp\u003e11.6.5.1 Symptoms of Lung Cancer 357\u003c\/p\u003e \u003cp\u003e11.6.5.2 Causes or Risk Factors of Lung Cancer 358\u003c\/p\u003e \u003cp\u003e11.6.5.3 Treatments Available for Lung Cancer 358\u003c\/p\u003e \u003cp\u003e11.6.5.4 Deep Learning in Lung Cancer 358\u003c\/p\u003e \u003cp\u003e11.6.6 Breast Cancer 359\u003c\/p\u003e \u003cp\u003e11.6.6.1 Symptoms of Breast Cancer 360\u003c\/p\u003e \u003cp\u003e11.6.6.2 Causes or Risk Factors of Breast Cancer 360\u003c\/p\u003e \u003cp\u003e11.6.6.3 Treatments Available for Breast Cancer 361\u003c\/p\u003e \u003cp\u003e11.6.7 Deep Learning in Breast Cancer 361\u003c\/p\u003e \u003cp\u003e11.6.8 Prostate Cancer 362\u003c\/p\u003e \u003cp\u003e11.6.9 Deep Learning in Prostate Cancer 362\u003c\/p\u003e \u003cp\u003e11.7 Future Aspects of Deep Learning in Cancer 363\u003c\/p\u003e \u003cp\u003e11.8 Conclusion 363\u003c\/p\u003e \u003cp\u003eReferences 363\u003c\/p\u003e \u003cp\u003e\u003cb\u003e12 Cardiovascular Disease Prediction Using Deep Neural Network for Older People 369\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eNagarjuna Telagam, B.Venkata Kranti and Nikhil Chandra Devarasetti\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e12.1 Introduction 370\u003c\/p\u003e \u003cp\u003e12.2 Proposed System Model 375\u003c\/p\u003e \u003cp\u003e12.2.1 Decision Tree Algorithm 375\u003c\/p\u003e \u003cp\u003e12.2.1.1 Confusion Matrix 376\u003c\/p\u003e \u003cp\u003e12.3 Random Forest Algorithm 381\u003c\/p\u003e \u003cp\u003e12.4 Variable Importance for Random Forests 383\u003c\/p\u003e \u003cp\u003e12.5 The Proposed Method Using a Deep Learning Model 384\u003c\/p\u003e \u003cp\u003e12.5.1 Prevention of Overfitting 386\u003c\/p\u003e \u003cp\u003e12.5.2 Batch Normalization 386\u003c\/p\u003e \u003cp\u003e12.5.3 Dropout Technique 386\u003c\/p\u003e \u003cp\u003e12.6 Results and Discussions 386\u003c\/p\u003e \u003cp\u003e12.6.1 Linear Regression 386\u003c\/p\u003e \u003cp\u003e12.6.2 Decision Tree Classifier 388\u003c\/p\u003e \u003cp\u003e12.6.3 Voting Classifier 389\u003c\/p\u003e \u003cp\u003e12.6.4 Bagging Classifier 389\u003c\/p\u003e \u003cp\u003e12.6.5 Naïve Bayes 390\u003c\/p\u003e \u003cp\u003e12.6.6 Logistic Regression 390\u003c\/p\u003e \u003cp\u003e12.6.7 Extra Trees Classifier 391\u003c\/p\u003e \u003cp\u003e12.6.8 K-Nearest Neighbor [KNN] Algorithm 391\u003c\/p\u003e \u003cp\u003e12.6.9 Adaboost Classifier 392\u003c\/p\u003e \u003cp\u003e12.6.10 Light Gradient Boost Classifier 393\u003c\/p\u003e \u003cp\u003e12.6.11 Gradient Boosting Classifier 393\u003c\/p\u003e \u003cp\u003e12.6.12 Stochastic Gradient Descent Algorithm 393\u003c\/p\u003e \u003cp\u003e12.6.13 Linear Support Vector Classifier 394\u003c\/p\u003e \u003cp\u003e12.6.14 Support Vector Machines 394\u003c\/p\u003e \u003cp\u003e12.6.15 Gaussian Process Classification 395\u003c\/p\u003e \u003cp\u003e12.6.16 Random Forest Classifier 395\u003c\/p\u003e \u003cp\u003e12.7 Evaluation Metrics 396\u003c\/p\u003e \u003cp\u003e12.8 Conclusion 401\u003c\/p\u003e \u003cp\u003eReferences 402\u003c\/p\u003e \u003cp\u003e\u003cb\u003e13 Machine Learning: The Capabilities and Efficiency of Computers in Life Sciences 407\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eShalini Yadav, Saurav Yadav, Shobhit Prakash Srivastava, Saurabh Kumar Gupta and Sudhanshu Mishra\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e13.1 Introduction 408\u003c\/p\u003e \u003cp\u003e13.2 Supervised Learning 410\u003c\/p\u003e \u003cp\u003e13.2.1 Workflow of Supervised Learning 410\u003c\/p\u003e \u003cp\u003e13.2.2 Decision Tree 410\u003c\/p\u003e \u003cp\u003e13.2.3 Support Vector Machine (SVM) 411\u003c\/p\u003e \u003cp\u003e13.2.4 Naive Bayes 413\u003c\/p\u003e \u003cp\u003e13.3 Deep Learning: A New Era of Machine Learning 414\u003c\/p\u003e \u003cp\u003e13.4 Deep Learning in Artificial Intelligence (AI) 416\u003c\/p\u003e \u003cp\u003e13.5 Using ML to Enhance Preventive and Treatment Insights 417\u003c\/p\u003e \u003cp\u003e13.6 Different Additional Emergent Machine Learning Uses 418\u003c\/p\u003e \u003cp\u003e13.6.1 Education 418\u003c\/p\u003e \u003cp\u003e13.6.2 Pharmaceuticals 419\u003c\/p\u003e \u003cp\u003e13.6.3 Manufacturing 419\u003c\/p\u003e \u003cp\u003e13.7 Machine Learning 419\u003c\/p\u003e \u003cp\u003e13.7.1 Neuroscience Research Advancements 420\u003c\/p\u003e \u003cp\u003e13.7.2 Finding Patterns in Astronomical Data 420\u003c\/p\u003e \u003cp\u003e13.8 Ethical and Social Issues Raised ! ! ! 421\u003c\/p\u003e \u003cp\u003e13.8.1 Reliability and Safety 421\u003c\/p\u003e \u003cp\u003e13.8.2 Transparency and Accountability 421\u003c\/p\u003e \u003cp\u003e13.8.3 Data Privacy and Security 421\u003c\/p\u003e \u003cp\u003e13.8.4 Malicious Use of AI 422\u003c\/p\u003e \u003cp\u003e13.8.5 Effects on Healthcare Professionals 422\u003c\/p\u003e \u003cp\u003e13.9 Future of Machine Learning in Healthcare 422\u003c\/p\u003e \u003cp\u003e13.9.1 A Better Patient Journey 422\u003c\/p\u003e \u003cp\u003e13.9.2 New Ways to Deliver Care 424\u003c\/p\u003e \u003cp\u003e13.10 Challenges and Hesitations 424\u003c\/p\u003e \u003cp\u003e13.10.1 Not Overlord Assistant Intelligent 424\u003c\/p\u003e \u003cp\u003e13.10.2 Issues with Unlabeled Data 425\u003c\/p\u003e \u003cp\u003e13.11 Concluding Thoughts 425\u003c\/p\u003e \u003cp\u003eAcknowledgments 426\u003c\/p\u003e \u003cp\u003eReferences 426\u003c\/p\u003e \u003cp\u003eIndex 431\u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Computer science [\u003ca title=\"See our other books on Computer science\" 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