{"product_id":"constitutive-activity-in-receptors-and-other-proteins-part-b-hardback-9780123812964","title":"Constitutive Activity in Receptors and Other Proteins, Part B (Hardback) 9780123812964","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eConstitutive Activity in Receptors and Other Proteins, Part B\u003c\/font\u003e\u003cbr\u003e\r\n\r\n\r\n\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cp\u003eThis volume of Methods in Enzymology covers the current methodology for the detection and assessment of constitutively active proteins. \u003c\/p\u003e\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eMelvin I. Simon (Volume editor)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780123812964, Elsevier Science\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 24 November 2010\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e708 pages\u003cbr\u003e22.9 x 15.1 x 3.7 cm, 1.1 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003e\u003cp\u003eThis volume of \u003ci\u003eMethods in Enzymology\u003c\/i\u003e covers the current methodology for the detection and assessment of constitutively active proteins. The chapters written by expert authors who are leaders in the field, provide hints and tricks not available in primary research publications.It is extensively referenced, with useful figures and tables throughout the volume.\u003c\/p\u003e\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e\u003col\u003e \u003col\u003e \u003cli\u003eIdentification and characterization of Steroidogenic Factor-1 inverse agonists. \u003c\/li\u003e \u003cp\u003eMabrouka Doghman, Franck Madoux, Peter Hodder, and Enzo Lalli\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eAssessment of inverse agonism for the angiotensin II type 1 receptor\u003c\/li\u003e \u003cp\u003eHiroshi Akazawa, Noritaka Yasuda, Shin-ichiro Miura, Issei Komuro\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eMeasurement of inverse agonism in BARs\u003c\/li\u003e \u003cp\u003eCarlos Alberto Taira\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eInverse agonism of antidepressants: in vitro and in vivo studies\u003c\/li\u003e \u003cp\u003eJoel Bockaert\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eDifferential inverse agonism at the human muscarinic M\u003csub\u003e3\u003c\/sub\u003e receptor\u003c\/li\u003e \u003cp\u003ePaola Casarosa\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eGhrelin Receptor: High Constitutive Activity and Methods for Developing Inverse Agonists.\u003c\/li\u003e \u003cp\u003eConstance Chollet\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eConstitutive activity and inverse agonism at the a1a and a1b adrenergic receptor subtypes.\u003c\/li\u003e \u003cp\u003eSusanna. Cotecchia\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eMeasurement of inverse agonism of the cannabinoid receptor\u003c\/li\u003e \u003cp\u003eTung Fong\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eConstitutively Active Thyrotropin (TSH) and Thyrotropin-Releasing Hormone (TRH) Receptors and Their Inverse Agonists\u003c\/li\u003e \u003cp\u003eMarvin C. Gershengorn\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eInverse retinoid agonists and neutral antagonists\u003c\/li\u003e \u003cp\u003eHinrich Gronemeyer\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e\n\u003cli\u003e?-Aminobutyric Acid Type A (GABA\u003csub\u003eA\u003c\/sub\u003e) Receptor Subtype Inverse Agonists as Therapeutic Agents in Cognition \u003c\/li\u003e \u003cp\u003eGabriella Guerrini and Ciciani Giovanna\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eAssays for inverse agonists in the visual system.\u003c\/li\u003e \u003cp\u003eMasahiro Kono\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eReceptor-driven identification of novel human A3 adenosine receptor antagonists as potential therapeutic agents\u003c\/li\u003e \u003cp\u003eSilvia Paoletta, Stephanie Federico, Giampiero Spalluto and Stefano Moro\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eInverse agonists of steroidogenic factor SF-1\u003c\/li\u003e \u003cp\u003eFabrice Piu and Andria L. Del Tredici\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eMethods to Measure G Protein Coupled Receptor Activity for the Identification of Inverse Agonists\u003c\/li\u003e \u003cp\u003eGabriel Barreda-Gómez, M.Teresa Giralt and Rafael Rodríguez-Puertas\u003c\/p\u003e    \u003cp\u003eSection II-- Novel Strategies and Techniques for Constitutive Activity and Inverse Agonism\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eUse of Pharmacoperones to Reveal GPCR Structural Components Associated with Receptor Activation and Trafficking\u003c\/li\u003e \u003cp\u003eJo Ann Janovick and P. Michael Conn\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eApplication of large-scale transiently transfected cells to functional assays of ion channels and other proteins.\u003c\/li\u003e \u003cp\u003eJun Chen, Sujatha Gopalakrishnan, Marc R Lake, and Bruce R Bianchi\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eQuantification of RNA Editing of the Serotonin 2C Receptor (5-HT2CR) Ex Vivo \u003c\/li\u003e \u003cp\u003eMaria Fe Lanfranco, Noelle C. Anastasio, Patricia K. Seitz, and Kathryn A. Cunningham \u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eStrategies for isolating constitutively-active and dominant-negative pheromone receptor mutants in yeast. \u003c\/li\u003e \u003cp\u003eMercedes Dosil and James B. Konopka\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eDevelopment of a GPR23 Cell-based ß-Lactamase Reporter Assay\u003c\/li\u003e \u003cp\u003ePaul H. Lee and Bonnie J. Hanson\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eComputational Modeling of Constitutively Active Mutants of GPCRs: C5a Receptor. \u003c\/li\u003e \u003cp\u003eGregory V. Nikiforovich and Thomas J. Baranski\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eTSH receptor monoclonal antibodies with agonist, antagonist and inverse agonist activities \u003c\/li\u003e \u003cp\u003eJane Sanders, Ricardo Núñez Miguel, Jadwiga Furmaniak, Bernard Rees Smith\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eCurrent standards, variations and pitfalls for the determination of constitutive TSHR activity in vitro\u003c\/li\u003e \u003cp\u003eSandra Mueller, Holger Jaeschke, Ralf Paschke \u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eTowards the Rational Design of Constitutively Active KCa3.1 Mutant Channels \u003c\/li\u003e \u003cp\u003eLine Garneau, Hélène Klein, Lucie Parent, Rémy Sauvé\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eFusion proteins as model systems for the analysis of constitutive GPCR activity\u003c\/li\u003e \u003cp\u003eErich H. Schneider, Roland Seifert \u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eScreening for Novel Constitutively Active CXCR2 Mutants and Their Cellular Effects \u003c\/li\u003e \u003cp\u003eGiljun Park, Tom Masi, Chang K. Choi, Heejung Kim, Jeffrey M. Becker, and Tim E. Sparer \u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eA method for parallel solid-phase synthesis of iodinated analogues of the cannabinoid receptor type I (CB1) inverse agonist rimonabant \u003c\/li\u003e \u003cp\u003eAlan C. Spivey and Chih-Chung Tseng\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eCoexpression systems as models for the analysis of constitutive GPCR activity\u003c\/li\u003e \u003cp\u003eRoland Seifert and Erich H. Schneider\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eModelling and simulation of inverse agonism dynamics \u003c\/li\u003e \u003cp\u003eLloyd J. Bridge \u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eDesign and Use of Constitutively Active STAT5 Constructs \u003c\/li\u003e \u003cp\u003eMichael A. Farrar\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eIn vitro and in vivo assays of protein kinase CK2 activity\u003c\/li\u003e \u003c\/ol\u003e \u003cp\u003eRenaud Prudent, Céline F. Sautel, Virginie Moucadel, Béatrice Laudet, Odilhe Filhol, and Claude Cochet\u003c\/p\u003e\n\u003c\/ol\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Cellular biology [\u003ca title=\"See our other books on Cellular biology\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Cellular%20biology%20%5Bcytology%5D%20%5BPSF%5D%22\"\u003ecytology PSF\u003c\/a\u003e], Molecular biology [\u003ca title=\"See our other books on Molecular biology\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Molecular%20biology%20%5BPSD%5D%22\"\u003ePSD\u003c\/a\u003e], Proteins [\u003ca title=\"See our other books on Proteins\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Proteins%20%5BPSBC%5D%22\"\u003ePSBC\u003c\/a\u003e], Biochemistry [\u003ca title=\"See our other books on Biochemistry\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Biochemistry%20%5BPSB%5D%22\"\u003ePSB\u003c\/a\u003e], Biophysics [\u003ca title=\"See our other books on Biophysics\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Biophysics%20%5BPHVN%5D%22\"\u003ePHVN\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Academic Press","offers":[{"title":"Default Title","offer_id":46649313689880,"sku":"9780123812964","price":122.99,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/products\/9780123812964_e7049c9f-0b7f-481a-91bf-2f0b602fca2d.jpg?v=1695014008","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/constitutive-activity-in-receptors-and-other-proteins-part-b-hardback-9780123812964","provider":"Freshly Printed Books","version":"1.0","type":"link"}