{"product_id":"concepts-and-models-for-drug-permeability-studies-cell-and-tissue-based-in-vitro-culture-models-hardback-9780081000946","title":"Concepts and Models for Drug Permeability Studies; Cell and Tissue based In Vitro Culture Models (Hardback) 9780081000946","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eConcepts and Models for Drug Permeability Studies\u003c\/font\u003e\u003cbr\u003e\r\n\u003cfont size=\"5\"\u003eCell and Tissue based In Vitro Culture Models\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cem\u003e\u003cp\u003eThe most important buccal, gastric, intestinal, pulmonary, nasal, vaginal, ocular, skin and blood-brain barrier in vitro models for predicting the permeability of drugs \u003c\/p\u003e\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eBruno Sarmento (Author)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780081000946, Elsevier Science\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 8 October 2015\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e408 pages\u003cbr\u003e22.9 x 15.1 x 2.7 cm, 0.55 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003e\u003cp\u003eThis book intends to be an updated compilation of the most important buccal, gastric, intestinal, pulmonary, nasal, vaginal, ocular, skin and blood-brain barrier in vitro models for predicting the permeability of drugs. \u003ci\u003eConcepts and Models for Drug Permeability Studies\u003c\/i\u003e focuses on different approaches and comprises of various models. Each model describes the protocol of seeding and conservation, the application for specific drugs, and takes into account the maintenance of physiologic characteristics and functionality of epithelium, from the simplest immortalized cell-based monoculture to the most complex engineered-tissue models. Chapters also discuss the equivalence between in vitro cell and tissue models and in vivo conditions, highlighting how each model may provisionally resemble a different drug absorption route.\u003c\/p\u003e\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e\u003cp\u003e1. Introduction\u003c\/p\u003e \u003cp\u003e2. Importance and applications of cell and tissue-based in vitro models for drug permeability screening in early stages of drug development\u003c\/p\u003e \u003cp\u003e3. Immortalized cell-based in vitro culture models for drug permeability studies\u003c\/p\u003e \u003cp\u003e4. Primary isolated cell-based in vitro culture models for drug permeability studies\u003c\/p\u003e \u003cp\u003e5. Tissue-based in vitro culture models for drug permeability studies\u003c\/p\u003e \u003cp\u003e6. Correlation between cell and tissue-based in vitro models for drug permeability screening with in vivo situation: Modeling and functional extrapolation\u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Cellular biology [\u003ca title=\"See our other books on Cellular biology\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Cellular%20biology%20%5Bcytology%5D%20%5BPSF%5D%22\"\u003ecytology PSF\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Woodhead Publishing","offers":[{"title":"Default Title","offer_id":46649103712536,"sku":"9780081000946","price":102.59,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/products\/9780081000946_6b0a9b82-c848-4cd7-b1be-4c4aabed59dd.jpg?v=1695004083","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/concepts-and-models-for-drug-permeability-studies-cell-and-tissue-based-in-vitro-culture-models-hardback-9780081000946","provider":"Freshly Printed Books","version":"1.0","type":"link"}