{"product_id":"computer-aided-vaccine-design-hardback-9781907568411","title":"Computer-Aided Vaccine Design (Hardback) 9781907568411","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eComputer-Aided Vaccine Design\u003c\/font\u003e\u003cbr\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003c\/p\u003e\n\u003cp\u003e\u003cfont size=\"4\"\u003eJoo Chuan Tong (Author), Shoba Ranganathan (Author)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9781907568411, Elsevier Science\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 31 July 2013\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e164 pages\u003cbr\u003e23.3 x 15.6 x 1.8 cm, 0.41 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003eComputational pre-screening of antigens is now routinely applied to the discovery of vaccine candidates.Computer-aided vaccine design is a comprehensive introduction to this exciting field of study. The book is intended to be a textbook for researchers and for courses in bioinformatics, as well as a laboratory reference guide. It is written mainly for biologists who want to understand the current methods of computer-aided vaccine design. The contents are designed to help biologists appreciate the underlying concepts and algorithms used, as well as limitations of the methods and strategies for their use. Chapters include: MHC and T cell responses; Immunoglobulins and B cell responses; Scientific publications and databases; Database design; Computational T cell vaccine design; Computational B cell vaccine design; infectious disease informatics; Vaccine safety and quality assessments; and Vaccine adjuvant informatics.\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e\u003cp\u003eList of figures\u003c\/p\u003e \u003cp\u003eList of abbreviations\u003c\/p\u003e \u003cp\u003eAbout the authors\u003c\/p\u003e \u003cp\u003ePreface\u003c\/p\u003e \u003cp\u003eChapter 1: MHC and T cell responses\u003c\/p\u003e \u003cp\u003eAbstract:\u003c\/p\u003e \u003cp\u003e1.1 Genetic organization of the MHC\u003c\/p\u003e \u003cp\u003e1.2 MHC structure\u003c\/p\u003e \u003cp\u003e1.3 MHC function\u003c\/p\u003e \u003cp\u003e1.4 Peptide binding\u003c\/p\u003e \u003cp\u003eChapter 2: Immunoglobulins and B cell responses\u003c\/p\u003e \u003cp\u003eAbstract:\u003c\/p\u003e \u003cp\u003e2.1 Types of immunoglobulins\u003c\/p\u003e \u003cp\u003e2.2 Immunoglobulin structure\u003c\/p\u003e \u003cp\u003e2.3 Immunoglobulin function\u003c\/p\u003e \u003cp\u003e2.4 Antigen binding\u003c\/p\u003e \u003cp\u003eChapter 3: Scientific publications and databases\u003c\/p\u003e \u003cp\u003eAbstract:\u003c\/p\u003e \u003cp\u003e3.1 Bibliographical information\u003c\/p\u003e \u003cp\u003e3.2 Searching the literature\u003c\/p\u003e \u003cp\u003e3.3 General databases containing information on genes and proteins\u003c\/p\u003e \u003cp\u003e3.4 Immunological databases\u003c\/p\u003e \u003cp\u003e3.5 Small molecule databases\u003c\/p\u003e \u003cp\u003eChapter 4: Database design\u003c\/p\u003e \u003cp\u003eAbstract:\u003c\/p\u003e \u003cp\u003e4.1 Fundamentals of database design\u003c\/p\u003e \u003cp\u003e4.2 ER diagram\u003c\/p\u003e \u003cp\u003e4.3 Normalization and normal forms\u003c\/p\u003e \u003cp\u003eChapter 5: Computational T cell vaccine design\u003c\/p\u003e \u003cp\u003eAbstract:\u003c\/p\u003e \u003cp\u003e5.1 Sequence-based methods\u003c\/p\u003e \u003cp\u003e5.2 Structure-based methods\u003c\/p\u003e \u003cp\u003e5.3 Broad-based T cell vaccine design\u003c\/p\u003e \u003cp\u003eChapter 6: Computational B cell vaccine design\u003c\/p\u003e \u003cp\u003eAbstract:\u003c\/p\u003e \u003cp\u003e6.1 Sequence-based methods\u003c\/p\u003e \u003cp\u003e6.2 Structure-based methods\u003c\/p\u003e \u003cp\u003eChapter 7: Infectious disease informatics\u003c\/p\u003e \u003cp\u003eAbstract:\u003c\/p\u003e \u003cp\u003e7.1 Infectious diseases in history\u003c\/p\u003e \u003cp\u003e7.2 Microbial sequence analysis\u003c\/p\u003e \u003cp\u003e7.3 Detecting natural selection in molecular evolution\u003c\/p\u003e \u003cp\u003eChapter 8: Vaccine safety and quality assessments\u003c\/p\u003e \u003cp\u003eAbstract:\u003c\/p\u003e \u003cp\u003e8.1 Assessment of ADME\/Tox deficiencies\u003c\/p\u003e \u003cp\u003e8.2 Assessment of allergenicity\u003c\/p\u003e \u003cp\u003eChapter 9: Vaccine adjuvant informatics\u003c\/p\u003e \u003cp\u003eAbstract:\u003c\/p\u003e \u003cp\u003e9.1 Virtual combinatorial library\u003c\/p\u003e \u003cp\u003e9.2 Chemical file formats\u003c\/p\u003e \u003cp\u003e9.3 Considerations for virtual library design\u003c\/p\u003e \u003cp\u003eIndex\u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Immunology [\u003ca title=\"See our other books on Immunology\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Immunology%20%5BMJCM%5D%22\"\u003eMJCM\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Woodhead Publishing","offers":[{"title":"Default Title","offer_id":46651788624152,"sku":"9781907568411","price":87.39,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/products\/9781907568411_b45f5037-e6ce-41c0-b765-8ea96fc64c7d.jpg?v=1696598741","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/computer-aided-vaccine-design-hardback-9781907568411","provider":"Freshly Printed Books","version":"1.0","type":"link"}