{"product_id":"clinical-immunology-principles-and-practice-hardback-9780702081651","title":"Clinical Immunology; Principles and Practice (Hardback) 9780702081651","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eClinical Immunology\u003c\/font\u003e\u003cbr\u003e\r\n\u003cfont size=\"5\"\u003ePrinciples and Practice\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cem\u003eStay up to date with both the basic science and clinical aspects of immunology\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eRobert R. Rich (Edited by), Thomas A. Fleisher (Edited by), Harry W. Schroeder Jr. (Edited by), Cornelia M. Weyand (Edited by), David B. Corry (Edited by), Jennifer M. Puck (Edited by)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780702081651, Elsevier Health Sciences\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 16 December 2022\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e1344 pages\u003cbr\u003e27.6 x 21.6 x 5.9 cm, 3.88 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003e\u003cp\u003eOffering \u003cb\u003eunique, comprehensive coverage of both basic science and clinical scenarios\u003c\/b\u003e, \u003ci\u003eClinical Immunology: Principles and Practice, 6th Edition\u003c\/i\u003e, brings you up to date with every aspect of this fast-changing field. It examines the molecular, cellular, and immunologic bases of immunologic diseases and their broader systemic implications; it also includes \u003cb\u003ecomplete coverage of common and uncommon immunologic disorders\u003c\/b\u003e. Updated with all the latest immunologic research and clinical implications, including \u003cb\u003ebreakthrough immunotherapies and molecular-based treatment protocols\u003c\/b\u003e, this fully revised edition provides authoritative guidance from some of the most respected global leaders in immunology in one complete, well-illustrated volume.\u003c\/p\u003e\n\u003cul\u003e \u003cli\u003eIncludes \u003cb\u003eextensive revisions that reflect rapidly expanding research and clinical advances\u003c\/b\u003e, including breakthrough drug and immunotherapies such as immune checkpoint inhibitors, immunotherapies for cancer, precision medicine, and transfusion medicine. \u003c\/li\u003e  \u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eContains \u003cb\u003enew chapters\u003c\/b\u003e on COVID-19, immune responses, and the role of the immune system; immunoregulatory deficiencies; immune checkpoints; CAR T cells, including new cellular-based immunotherapy; gene therapy, including CRISPR and gene selection; and a clinically focused chapter on asthma.\u003c\/li\u003e \u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eProvides \u003cb\u003enew genetics content\u003c\/b\u003e focused on data applications.\u003c\/li\u003e \u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eAddresses \u003cb\u003enotable advances in key areas\u003c\/b\u003e such as the importance of the microbiota to normal immune system development and to the pathogenesis of immunologic and inflammatory diseases; relationships between the innate and adaptive immune systems; progress in rapid and cost-effective genomics; cell signaling pathways and the structure of cell-surface molecules; and many more. \u003c\/li\u003e \u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eCovers \u003cb\u003ehot topics\u003c\/b\u003e such as the role of genetics and genomics in immune response and immunologic disease, atherosclerosis, recurrent fever syndromes, aging and deficiencies of innate immunity, the role of microbiota in normal immune system development and in the pathogenesis of immunologic and inflammatory diseases, and novel therapeutics.\u003c\/li\u003e \u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eFeatures a \u003cb\u003euser-friendly format\u003c\/b\u003e with color-coded boxes highlighting critical information on Key Concepts, Clinical Pearls, Clinical Relevance, and Therapeutic Principles.\u003c\/li\u003e \u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eSummarizes \u003cb\u003epromising research and development\u003c\/b\u003e anticipated over the next 5–10 years with \"On the Horizon\" boxes and discussions of translational research.\u003c\/li\u003e \u003cb\u003e  \u003c\/b\u003e\u003cp\u003e \u003c\/p\u003e\n\u003cli\u003eAn eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.\u003c\/li\u003e \u003c\/ul\u003e\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e\u003cb\u003ePART I Principles of Immune Response\u003c\/b\u003e\u003cbr\u003e1 The Human Immune Response\u003cbr\u003e2 Organization of the Immune System\u003cbr\u003e3 Innate Immunity\u003cbr\u003e4 Antigen Receptor Genes, Gene Products, and Co-Receptors\u003cbr\u003e5 The Major Histocompatibility Complex\u003cbr\u003e6 Antigens and Antigen Presentation\u003cbr\u003e7 B-Cell Development and Differentiation\u003cbr\u003e8 Immunoglobulin Function\u003cbr\u003e9 T-Cell Development\u003cbr\u003e10 T-Cell Activation and Tolerance\u003cbr\u003e11 Helper T-Cell Subsets and Control of the Inflammatory Response\u003cbr\u003e12 Cytotoxic T Lymphocytes and Natural Killer Cells\u003cbr\u003e13 Regulatory Immune Cells\u003cbr\u003e14 Cytokines and Cytokine Receptors\u003cbr\u003e15 Chemokines and Chemokine Receptors\u003cbr\u003e16 Lymphocyte Adhesion and Trafficking\u003cbr\u003e17 Death Pathways and Immunogenicity\u003cbr\u003e\u003cb\u003ePART II Fundamentals of Host-Environmental Interactions\u003c\/b\u003e\u003cbr\u003e18 Human Genomics in Immunology\u003cbr\u003e19 Regulatory RNA in Immunologic Diseases\u003cbr\u003e20 Immunometabolism\u003cbr\u003e21 Immune Deficiencies at the Extremes of Age\u003cbr\u003e22 The Microbiota in Immunity and Inflammation\u003cbr\u003e\u003cb\u003ePART III Host Defenses to Infectious Agents\u003c\/b\u003e\u003cbr\u003e23 Immunology of the Skin\u003cbr\u003e24 Immunology of Mucosal Surfaces\u003cbr\u003e25 Host Defenses to Viruses\u003cbr\u003e26 Host Defenses to Intracellular Bacteria\u003cbr\u003e27 Host Defenses to Extracellular Bacteria, Including Spirochetes\u003cbr\u003e28 Host Defenses to Fungi\u003cbr\u003e29 Host Defenses to Protozoa\u003cbr\u003e30 Host Defenses to Helminth Infection\u003cbr\u003e31 Emerging Pandemic Infectious Disease Threats\u003cbr\u003e\u003cb\u003ePART IV Immune Deficiency and Immune Regulatory Disorders\u003c\/b\u003e\u003cbr\u003e32 Approach to the Evaluation of the Patient With Suspected Immunodeficiency\u003cbr\u003e33 Primary Antibody Deficiencies\u003cbr\u003e34 Primary T-Cell Immunodeficiencies\u003cbr\u003e35 Genetic Disorders of Interferons-, Interleukin-17, Interleukin-18, and Nuclear Factor-?B-Mediated Immunity\u003cbr\u003e36 Hemophagocytic Lymphohistiocytosis\u003cbr\u003e37 Autoinflammatory Syndromes\u003cbr\u003e38 Immune Regulatory Disorders\u003cbr\u003e39 Neutrophils and Neutrophil Disorders\u003cbr\u003e40 Complement and Complement Disorders\u003cbr\u003e41 Human Immunodeficiency Virus Infection and Acquired Immunodeficiency Syndrome\u003cbr\u003e42 Autoantibody-Mediated Phenocopies of Primary Immunodeficiency Diseases\u003cbr\u003e\u003cb\u003ePART V Allergic Diseases\u003c\/b\u003e\u003cbr\u003e43 Allergic Airway Diseases\u003cbr\u003e44 Mast Cells and Mast Cell Disorders\u003cbr\u003e45 Eosinophils and Eosinophilic Disorders\u003cbr\u003e46 Urticaria, Angioedema, and Anaphylaxis\u003cbr\u003e47 Allergic Reactions to Stinging and Biting Insects\u003cbr\u003e48 Atopic and Contact Dermatitis\u003cbr\u003e49 Food Allergy\u003cbr\u003e50 Drug Hypersensitivity\u003cbr\u003e\u003cb\u003ePART VI Systemic Immune Diseases\u003c\/b\u003e\u003cbr\u003e51 Mechanisms of Autoimmunity\u003cbr\u003e52 Systemic Lupus Erythematosus\u003cbr\u003e53 Rheumatoid Arthritis\u003cbr\u003e54 Juvenile Idiopathic Arthritis\u003cbr\u003e55 Sjögren’s Syndrome\u003cbr\u003e56 Scleroderma-Systemic Sclerosis\u003cbr\u003e57 Inflammatory Muscle Diseases\u003cbr\u003e58 Spondyloarthritis\u003cbr\u003e59 Small- and Medium-Vessel Primary Vasculitis\u003cbr\u003e60 Large Vessel Vasculitides\u003cbr\u003e61 Antiphospholipid Syndrome\u003cbr\u003e\u003cb\u003ePART VII Organ-Specific Inflammatory Disease\u003c\/b\u003e\u003cbr\u003e62 Immunohematologic Disorders\u003cbr\u003e63 Bullous Diseases of the Skin and Mucous Membranes\u003cbr\u003e64 Immunology of Psoriasis\u003cbr\u003e65 Myasthenia Gravis\u003cbr\u003e66 Multiple Sclerosis\u003cbr\u003e67 Autoimmune Peripheral Neuropathies\u003cbr\u003e68 Immunologic Renal Diseases\u003cbr\u003e69 Immunologic Mechanisms of Atherosclerosis and Myocarditis\u003cbr\u003e70 Autoimmune Thyroid Diseases\u003cbr\u003e71 Type 1 Diabetes\u003cbr\u003e72 Immunologic Lung Diseases, 919\u003cbr\u003e73 Chronic Obstructive Pulmonary Disease and Emphysema\u003cbr\u003e74 Immunologic Ocular Disease\u003cbr\u003e75 Immunologic Diseases of the Gastrointestinal Tract\u003cbr\u003e76 Inflammatory Hepatobiliary Diseases\u003cbr\u003e\u003cb\u003ePART VIII Immunology and Immunotherapy of Neoplasia\u003c\/b\u003e\u003cbr\u003e77 Lymphoid Leukemias\u003cbr\u003e78 Lymphomas\u003cbr\u003e79 Monoclonal Gammopathies\u003cbr\u003e80 Immune Responses to Solid Tumors and Immune Checkpoint Therapy\u003cbr\u003e81 CAR T-Cell Therapy\u003cbr\u003e\u003cb\u003ePART IX Medical Management of Immunological Diseases\u003c\/b\u003e\u003cbr\u003e82 Immunoglobulin Therapy: Replacement and Immunomodulation\u003cbr\u003e83 Glucocorticoids\u003cbr\u003e84 Immunomodulating Drugs\u003cbr\u003e85 Protein Kinase Antagonists\u003cbr\u003e86 Biologic Response Modifiers\u003cbr\u003e87 Vaccines\u003cbr\u003e88 Allergen Immunotherapy for Allergic Diseases\u003cbr\u003e\u003cb\u003ePART X Transplantation\u003cbr\u003e\u003c\/b\u003e89 Solid Organ Transplantation: Rejection, Immunosuppression, and Tolerance\u003cbr\u003e90 Allogeneic Transplantation for Immunodeficiency\u003cbr\u003e91 Gene Therapy for Primary Immune Deficiency Diseases\u003cbr\u003e92 Hematopoietic Stem Cell Transplantation for Malignant Diseases\u003cbr\u003e\u003cb\u003ePART XI Diagnostic Immunology\u003cbr\u003e\u003c\/b\u003e93 Flow Cytometry\u003cbr\u003e94 Assessment of Functional Immune Responses in Lymphocytes\u003cbr\u003e95 Assessment of Neutrophil Function\u003cbr\u003e96 Assessment of Human Allergic Diseases\u003cbr\u003e\u003cb\u003eAppendix 1: Selected CD Molecules and Their Characteristics\u003cbr\u003eAppendix 2: Laboratory Reference Values\u003cbr\u003eIndex\u003c\/b\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Immunology [\u003ca title=\"See our other books on Immunology\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Immunology%20%5BMJCM%5D%22\"\u003eMJCM\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Elsevier","offers":[{"title":"Default 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