{"product_id":"chemistry-of-biologically-potent-natural-products-and-synthetic-compounds-hardback-9781119640349","title":"Chemistry of Biologically Potent Natural Products and Synthetic Compounds (Hardback) 9781119640349","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eChemistry of Biologically Potent Natural Products and Synthetic Compounds\u003c\/font\u003e\u003cbr\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003c\/p\u003e\n\u003cp\u003e\u003cfont size=\"4\"\u003eShahid Ul Islam (Edited by), S Ul–Islam (Author), Javid Ahmad Banday (Edited by)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9781119640349, Wiley\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 24 August 2021\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e432 pages\u003cbr\u003e1 x 1 x 1 cm, 0.454 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003e\u003cp\u003eIn view of their promising biological and pharmaceutical activities, natural product inspired and heterocyclic compounds have recently gained a reputation in the field of medicinal chemistry. Over the past decades, intensive research efforts have been ongoing to understand the synthesis, biochemistry and engineering involved in their preparation and action mechanisms.\u003c\/p\u003e \u003cp\u003eSeveral novel natural product derivatives, heterocyclic and other synthetic compounds, have been reported to have shown interesting biological activities including anticancer, antimicrobial, anti-inflammatory, anti-glycemic, anti-allergy and antiviral etc.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eChemistry of Biologically Potent Natural Products and Synthetic Compounds\u003c\/i\u003e provides up-to-date information on new developments and most recent medicinal applications of the natural products and derivatives, as well as the chemistry and synthesis of heterocyclic and other related compounds.\u003c\/p\u003e\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e\u003cp\u003ePreface xiii\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 Medicinal Importance of Plant Metabolites 1\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eSunita Panchawat and Chetna Ameta\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e1.1 Introductory Note 1\u003c\/p\u003e \u003cp\u003e1.2 Primary and Secondary Metabolites 3\u003c\/p\u003e \u003cp\u003e1.3 Functional Roles of Secondary Metabolites 3\u003c\/p\u003e \u003cp\u003e1.4 Source and Production of Secondary Metabolites 4\u003c\/p\u003e \u003cp\u003e1.5 Classification of Secondary Metabolic Substances 7\u003c\/p\u003e \u003cp\u003e1.5.1 Terpenes 8\u003c\/p\u003e \u003cp\u003e1.5.2 Phenol-Based Compounds 9\u003c\/p\u003e \u003cp\u003e1.5.3 Nitrogen-Containing Secondary Metabolites 10\u003c\/p\u003e \u003cp\u003e1.5.3.1 Alkaloids 10\u003c\/p\u003e \u003cp\u003e1.5.4 Secondary Metabolites Having Sulfur 11\u003c\/p\u003e \u003cp\u003e1.6 Bioactivity of Secondary Metabolites 12\u003c\/p\u003e \u003cp\u003e1.6.1 As Antioxidants 12\u003c\/p\u003e \u003cp\u003e1.6.2 As Antimicrobials 13\u003c\/p\u003e \u003cp\u003e1.6.3 As Anti-Diabetics Agents 13\u003c\/p\u003e \u003cp\u003e1.7 Conclusion and Future Perspectives 14\u003c\/p\u003e \u003cp\u003eReferences 14\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 Advances in Natural Products-Based Antiviral Agents 21\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eZhipeng Fu, Luis Menéndez-Arias, Xinyong Liu and Peng Zhan\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2.1 Introduction 21\u003c\/p\u003e \u003cp\u003e2.2 Anti-HIV Agents 22\u003c\/p\u003e \u003cp\u003e2.2.1 Terpenes 23\u003c\/p\u003e \u003cp\u003e2.2.2 Phenylpropanoids 24\u003c\/p\u003e \u003cp\u003e2.2.3 Anthraquinones 25\u003c\/p\u003e \u003cp\u003e2.2.4 Alkaloids 26\u003c\/p\u003e \u003cp\u003e2.3 Natural Alkaloids With Activity Against HBV and HCV Infections 26\u003c\/p\u003e \u003cp\u003e2.4 Anti-Influenza Virus Agents 28\u003c\/p\u003e \u003cp\u003e2.5 Natural Products Active Against Herpesviruses 30\u003c\/p\u003e \u003cp\u003e2.6 Natural Products Against Chikungunya Virus 31\u003c\/p\u003e \u003cp\u003e2.7 Natural Products Targeting Dengue Virus 32\u003c\/p\u003e \u003cp\u003e2.8 Natural Products Targeting Coronaviruses 33\u003c\/p\u003e \u003cp\u003e2.9 Natural Products Against Other Viral Infections 36\u003c\/p\u003e \u003cp\u003e2.10 Conclusion 37\u003c\/p\u003e \u003cp\u003eAcknowledgements 37\u003c\/p\u003e \u003cp\u003eReferences 37\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Bioactive Component of Black Pepper-Piperine: Structure-Activity Relationship and Its Broad-Spectrum Activity—An Overview 43\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eArthi Sivashanmugam and Sivan Velmathi\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eList of Abbreviations 44\u003c\/p\u003e \u003cp\u003e3.1 Introduction: What is a Natural Product? 44\u003c\/p\u003e \u003cp\u003e3.2 Black Pepper 48\u003c\/p\u003e \u003cp\u003e3.2.1 Constituents of Black Pepper 51\u003c\/p\u003e \u003cp\u003e3.2.2 Major Alkaloids of Black Pepper 51\u003c\/p\u003e \u003cp\u003e3.3 Piperine—Active Molecule of Pepper 52\u003c\/p\u003e \u003cp\u003e3.3.1 Isolation of Piperine 52\u003c\/p\u003e \u003cp\u003e3.3.2 Piperine as Potential Drug 54\u003c\/p\u003e \u003cp\u003e3.3.2.1 Metabolism of Piperine 54\u003c\/p\u003e \u003cp\u003e3.3.2.2 Structure-Activity Relationship 55\u003c\/p\u003e \u003cp\u003e3.3.2.3 Piperine and Piperine Analogs 59\u003c\/p\u003e \u003cp\u003e3.3.2.4 Synergistic Activity of Piperine 72\u003c\/p\u003e \u003cp\u003e3.4 Overall Summary and Conclusion 88\u003c\/p\u003e \u003cp\u003eReferences 89\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Chemoenzymatic Synthesis of Pharmacologically Active Compounds Containing Chiral 1,2-Amino Alcohol Moiety 93\u003cbr\u003e\u003c\/b\u003e\u003ci\u003ePankaj Gupta and Neha Mahajan\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4.1 Introduction 94\u003c\/p\u003e \u003cp\u003e4.1.1 Chirality 94\u003c\/p\u003e \u003cp\u003e4.1.2 Biocatalysis 96\u003c\/p\u003e \u003cp\u003e4.1.2.1 Biocatalysis is Green and Sustainable 97\u003c\/p\u003e \u003cp\u003e4.1.2.2 Industrial Applications of Biocatalysts 98\u003c\/p\u003e \u003cp\u003e4.1.3 Vicinal Amino Alcohols 99\u003c\/p\u003e \u003cp\u003e4.2 Synthetic Approaches Toward 1,2-Amino Alcohols 102\u003c\/p\u003e \u003cp\u003e4.2.1 Chemoenzymatic Synthesis of L-Norephedrine 102\u003c\/p\u003e \u003cp\u003e4.2.2 Synthesis of Valinol 106\u003c\/p\u003e \u003cp\u003e4.2.3 Chemoenzymatic Synthesis of Atazanavir 107\u003c\/p\u003e \u003cp\u003e4.2.4 Chemoenzymatic Synthesis of Levamisole 107\u003c\/p\u003e \u003cp\u003e4.2.5 Chemoenzymatic Synthesis of Optically Active (\u003ci\u003eR\u003c\/i\u003e)- and (\u003ci\u003eS\u003c\/i\u003e)-Aryloxypropanolamines 108\u003c\/p\u003e \u003cp\u003e4.2.6 Chemoenzymatic Preparation of \u003ci\u003eTrans\u003c\/i\u003e-(1\u003ci\u003eR\u003c\/i\u003e,2\u003ci\u003eR\u003c\/i\u003e)-and \u003ci\u003eCis \u003c\/i\u003e(1\u003ci\u003eS\u003c\/i\u003e,2\u003ci\u003eR\u003c\/i\u003e)-1-Amino-2-Indanol 112\u003c\/p\u003e \u003cp\u003e4.2.7 Synthesis of Enantiomerically Pure 2-Aminopentane-1,3-Diol and 2-Amino-1,3,4-Butanetriol (ABT) 113\u003c\/p\u003e \u003cp\u003e4.2.8 Synthesis of Optically Active Cytoxazone 115\u003c\/p\u003e \u003cp\u003e4.2.9 Chemoenzymatic and Highly Integrated Synthesis of (\u003ci\u003eS\u003c\/i\u003e)-Tembamide 116\u003c\/p\u003e \u003cp\u003e4.2.10 Chemoenzymatic Synthesis of Paclitaxel C\u003csub\u003e13\u003c\/sub\u003e Side Chain 117\u003c\/p\u003e \u003cp\u003e4.3 Conclusion 118\u003c\/p\u003e \u003cp\u003eAcknowledgements 119\u003c\/p\u003e \u003cp\u003eReferences 119\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 1,4-Naphthoquinone: A Privileged Structural Framework in Drug Discovery 133\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eUmar Ali Dar, Mehnaz Kamal and Shakeel A. Shah\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5.1 Introduction 133\u003c\/p\u003e \u003cp\u003e5.1.1 Overview 134\u003c\/p\u003e \u003cp\u003e5.2 Various Targets of 1,4-Naphthoquinone for Its Actions 135\u003c\/p\u003e \u003cp\u003e5.2.1 Bacterial Topoisomerase II-DNA Gyrase for Antibacterial Action 135\u003c\/p\u003e \u003cp\u003e5.2.2 Mammalian Topoisomerases I and II for Antitumor Action 135\u003c\/p\u003e \u003cp\u003e5.2.3 HIV-1 Integrase and Proteinase for or Antiviral Action 135\u003c\/p\u003e \u003cp\u003e5.2.4 Dihydroorotate Dehydrogenase for Antimalarial Action 136\u003c\/p\u003e \u003cp\u003e5.2.5 Trypanothione and Trypanothione Reductase (TryR) for Leishmanicidal Action 137\u003c\/p\u003e \u003cp\u003e5.2.6 Mitochondrial Cytochrome (Coenzyme Q) for Antifungal Action 137\u003c\/p\u003e \u003cp\u003e5.3 Antifungal Activity 137\u003c\/p\u003e \u003cp\u003e5.4 Antibacterial Activities 140\u003c\/p\u003e \u003cp\u003e5.5 Anticancer Activity 142\u003c\/p\u003e \u003cp\u003e5.6 Antileishmanial Activity 145\u003c\/p\u003e \u003cp\u003e5.7 Antimalarial Activity 147\u003c\/p\u003e \u003cp\u003e5.8 Antiviral Activity 149\u003c\/p\u003e \u003cp\u003e5.9 Conclusion 149\u003c\/p\u003e \u003cp\u003eAcknowledgments 150\u003c\/p\u003e \u003cp\u003eReferences 150\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 Design and Synthesis of Spirobiisoxazoline Derivatives 155\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eK. Jones Madhuswapnaja, Satyanarayana Yennam and Murthy Chavali\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6.1 Introduction 155\u003c\/p\u003e \u003cp\u003e6.2 Literature Review on Spiroisoxazolines 157\u003c\/p\u003e \u003cp\u003e6.2.1 Chemistry 157\u003c\/p\u003e \u003cp\u003e6.2.2 Previous Approaches 159\u003c\/p\u003e \u003cp\u003e6.2.3 Biological Importance 163\u003c\/p\u003e \u003cp\u003e6.3 Literature Review on Quinones 166\u003c\/p\u003e \u003cp\u003e6.3.1 Chemistry 166\u003c\/p\u003e \u003cp\u003e6.3.2 Synthetic Approach 167\u003c\/p\u003e \u003cp\u003e6.3.3 Biological Importance 169\u003c\/p\u003e \u003cp\u003e6.4 Review on 1,3 Dipolar Cycloadditions of Oxime Chloride With Allenoates 171\u003c\/p\u003e \u003cp\u003e6.5 Present Work; Spirobiisoxazoline 172\u003c\/p\u003e \u003cp\u003e6.5.1 Results and Discussion 172\u003c\/p\u003e \u003cp\u003e6.5.1.1 Synthetic Studies 172\u003c\/p\u003e \u003cp\u003e6.5.1.2 Spectral Analysis 176\u003c\/p\u003e \u003cp\u003e6.5.2 Experimental Section 178\u003c\/p\u003e \u003cp\u003e6.6 Conclusion 179\u003c\/p\u003e \u003cp\u003eReferences 179\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 Potential of Metal Complexes for the Treatment of Cancer: Current Update and Future Prospective 183\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eShipra Yadav\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7.1 Introduction 184\u003c\/p\u003e \u003cp\u003e7.2 Conclusion and Future Prospective 195\u003c\/p\u003e \u003cp\u003eReferences 196\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 Design, Synthesis, and Biological Evaluation of Aziridynyl Quinone Derivatives 205\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eK. Jones Madhuswapnaja, Satyanarayana Yennam and Murthy Chavali\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8.1 Introduction 206\u003c\/p\u003e \u003cp\u003e8.2 Aziridines 207\u003c\/p\u003e \u003cp\u003e8.2.1 Literature Review 207\u003c\/p\u003e \u003cp\u003e8.2.2 Synthetic Approach 208\u003c\/p\u003e \u003cp\u003e8.2.3 Biological Importance 209\u003c\/p\u003e \u003cp\u003e8.3 Quinones 211\u003c\/p\u003e \u003cp\u003e8.3.1 Literature Review 211\u003c\/p\u003e \u003cp\u003e8.3.2 Synthetic Approach 213\u003c\/p\u003e \u003cp\u003e8.3.3 Biological Importance 215\u003c\/p\u003e \u003cp\u003e8.4 Aziridinyl Quinone Derivatives 217\u003c\/p\u003e \u003cp\u003e8.4.1 Present Work 219\u003c\/p\u003e \u003cp\u003e8.4.2 Synthetic Studies 220\u003c\/p\u003e \u003cp\u003e8.4.2.1 Confirmation of Regioisomers 63 and 63a 223\u003c\/p\u003e \u003cp\u003e8.4.2.2 Confirmation of Regioselectivity for Diaziridinyl Compounds 227\u003c\/p\u003e \u003cp\u003e8.4.3 Biological Evaluation 228\u003c\/p\u003e \u003cp\u003e8.4.3.1 Antibacterial Activity 229\u003c\/p\u003e \u003cp\u003e8.4.3.2 Minimum Bactericidal Concentration 230\u003c\/p\u003e \u003cp\u003e8.4.3.3 Biofilm Inhibition Assay 233\u003c\/p\u003e \u003cp\u003e8.4.3.4 Antifungal Activity 235\u003c\/p\u003e \u003cp\u003e8.4.3.5 Minimum Fungicidal Concentration 237\u003c\/p\u003e \u003cp\u003e8.4.3.6 Cytotoxic Activity 237\u003c\/p\u003e \u003cp\u003e8.4.4 Experimental Section 241\u003c\/p\u003e \u003cp\u003e8.4.4.1 Chemistry 241\u003c\/p\u003e \u003cp\u003e8.4.4.2 Biological Studies 243\u003c\/p\u003e \u003cp\u003e8.5 Conclusion 246\u003c\/p\u003e \u003cp\u003eReferences 247\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 Exploring the Promising Anticancer and Antimicrobial Potential of Bioactive Triazoles and Their Related Compounds 251\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eManzoor Ahmad Malik, Ovas Ahmad Dar, Nitu Singh, Gulshitab Aalam and Athar Adil Hashmi\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9.1 Introduction 252\u003c\/p\u003e \u003cp\u003e9.2 Anticancer Triazole Derivatives 256\u003c\/p\u003e \u003cp\u003e9.3 Antimicrobial Triazole Derivatives 267\u003c\/p\u003e \u003cp\u003e9.4 Conclusion 275\u003c\/p\u003e \u003cp\u003eReferences 276\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 Fused Triazolo Isoquinoline Derivatives—Design, Synthesis, and Biological Evaluation 281\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eK. Jones Madhuswapnaja, Satyanarayana Yennam and Murthy Chavali\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10.1 Introduction 282\u003c\/p\u003e \u003cp\u003e10.2 Literature Review on 1,2,4 Triazoles 283\u003c\/p\u003e \u003cp\u003e10.2.1 Chemistry 283\u003c\/p\u003e \u003cp\u003e10.2.2 Synthetic Approach 284\u003c\/p\u003e \u003cp\u003e10.2.3 Biological Importance 287\u003c\/p\u003e \u003cp\u003e10.3 Review on Isoquinoline and Fused Triazolo Isoquinolines 292\u003c\/p\u003e \u003cp\u003e10.4 Present Work 294\u003c\/p\u003e \u003cp\u003e10.5 Results and Discussion 294\u003c\/p\u003e \u003cp\u003e10.5.1 Synthetic Studies 294\u003c\/p\u003e \u003cp\u003e10.5.1.1 Confirmation of Regioisomer 298\u003c\/p\u003e \u003cp\u003e10.5.2 Spectral Analysis 299\u003c\/p\u003e \u003cp\u003e10.5.2.1 1H NMR Spectral and Mass Analysis 299\u003c\/p\u003e \u003cp\u003e10.5.2.2 13C NMR Spectral Analysis 299\u003c\/p\u003e \u003cp\u003e10.5.3 Biological Studies 299\u003c\/p\u003e \u003cp\u003e10.5.3.1 Antifungal Activity 300\u003c\/p\u003e \u003cp\u003e10.5.3.2 Minimum Fungicidal Concentration 300\u003c\/p\u003e \u003cp\u003e10.5.3.3 Ergosterol Biosynthesis Inhibition 303\u003c\/p\u003e \u003cp\u003e10.5.3.4 Cytotoxic Activity 305\u003c\/p\u003e \u003cp\u003e10.5.4 Molecular Docking Studies 305\u003c\/p\u003e \u003cp\u003e10.5.5 Experimental Section 309\u003c\/p\u003e \u003cp\u003e10.5.5.1 Chemistry 309\u003c\/p\u003e \u003cp\u003e10.5.5.2 Biological Studies 311\u003c\/p\u003e \u003cp\u003e10.5.6 Molecular Modeling Procedure 314\u003c\/p\u003e \u003cp\u003e10.6 Conclusion 314\u003c\/p\u003e \u003cp\u003eReferences 315\u003c\/p\u003e \u003cp\u003e\u003cb\u003e11 Amide as a Potential Pharmacophore for Drug Designing of Novel Anticonvulsant Compounds 319\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eMehnaz Kamal, Talha Jawaid, Umar Ali Dar and Shakeel A. Shah\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e11.1 Introduction 320\u003c\/p\u003e \u003cp\u003e11.2 Chemistry of Amides 321\u003c\/p\u003e \u003cp\u003e11.2.1 Synthesized Methods Utilized for Amide Bond Formation 321\u003c\/p\u003e \u003cp\u003e11.2.2 Amide Pharmacophore Containing Anticonvulsant Drug 322\u003c\/p\u003e \u003cp\u003e11.2.3 Anticonvulsant Activity 322\u003c\/p\u003e \u003cp\u003e11.3 Conclusion 337\u003c\/p\u003e \u003cp\u003eAcknowledgments 337\u003c\/p\u003e \u003cp\u003eReferences 337\u003c\/p\u003e \u003cp\u003e\u003cb\u003e12 Nitric Oxide, Carbon Monoxide, and Hydrogen Sulfide as Biologically Important Signaling Molecules With the Significance of Their Respective Donors in Ophthalmic Diseases 343\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eR. C. Maurya and J. M. Mir\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e12.1 Introduction 344\u003c\/p\u003e \u003cp\u003e12.2 A Meaningful Introduction to Gasotransmitters 346\u003c\/p\u003e \u003cp\u003e12.3 Biosynthesis and Target of NO, CO, and H\u003csub\u003e2\u003c\/sub\u003eS 347\u003c\/p\u003e \u003cp\u003e12.3.1 Biological Synthesis and Target of NO 347\u003c\/p\u003e \u003cp\u003e12.3.2 Biological Production and Target of CO 349\u003c\/p\u003e \u003cp\u003e12.3.3 Biosynthesis and Target Sites of H\u003csub\u003e2\u003c\/sub\u003eS 353\u003c\/p\u003e \u003cp\u003e12.4 Gasotransmitters in the Mission of Vision (Eye-Health Contribution) 357\u003c\/p\u003e \u003cp\u003e12.4.1 NO News is Good News for Eyes: NO Donors for the Treatment of Eye Diseases 357\u003c\/p\u003e \u003cp\u003e12.4.1.1 Nitric Oxide Releasing Molecules (NORMS) and the IOP 359\u003c\/p\u003e \u003cp\u003e12.4.2 Carbon Monoxide, CORMS, and the Ocular System 363\u003c\/p\u003e \u003cp\u003e12.4.3 Hydrogen Sulfide and Ophthalmic Diseases 367\u003c\/p\u003e \u003cp\u003e12.5 Concluding Remarks and Future Outlook 368\u003c\/p\u003e \u003cp\u003eReferences 368\u003c\/p\u003e \u003cp\u003e\u003cb\u003e13 Influence of \u003ci\u003erol \u003c\/i\u003eGenes for Enhanced Biosynthesis of Potent Natural Products 379\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eErum Dilshad, Huma Noor, Nabgha Nosheen, Syeda Rehab Gilani, Umar Ali and Mubarak Ali Khan\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e13.1 Introduction 380\u003c\/p\u003e \u003cp\u003e13.2 Secondary Metabolites or Natural Products 381\u003c\/p\u003e \u003cp\u003e13.2.1 Classes of Natural Products (Secondary Metabolites) 382\u003c\/p\u003e \u003cp\u003e13.2.1.1 Terpenoids 382\u003c\/p\u003e \u003cp\u003e13.2.1.2 Phenolic Compounds 383\u003c\/p\u003e \u003cp\u003e13.2.1.3 Alkaloids 383\u003c\/p\u003e \u003cp\u003e13.2.2 Strategies to Enhance Natural Products 383\u003c\/p\u003e \u003cp\u003e13.2.2.1 Plant Cell Culture (Somaclonal Variation) 384\u003c\/p\u003e \u003cp\u003e13.2.2.2 Genetic Transformation of Plant Cell 384\u003c\/p\u003e \u003cp\u003e13.2.2.3 Multiple Gene Transfer Through Improving Vectors 385\u003c\/p\u003e \u003cp\u003e13.2.3 Genetic Engineering\/Metabolic Engineering 385\u003c\/p\u003e \u003cp\u003e13.3 \u003ci\u003erol \u003c\/i\u003eGenes 386\u003c\/p\u003e \u003cp\u003e13.3.1 Origin of \u003ci\u003erol \u003c\/i\u003eGenes 387\u003c\/p\u003e \u003cp\u003e13.3.2 Types of \u003ci\u003erol \u003c\/i\u003eGenes 388\u003c\/p\u003e \u003cp\u003e13.3.2.1 The rolA Gene 388\u003c\/p\u003e \u003cp\u003e13.3.2.2 The rolB Gene 389\u003c\/p\u003e \u003cp\u003e13.3.2.3 The rolC Gene 390\u003c\/p\u003e \u003cp\u003e13.3.2.4 The rolD Gene 391\u003c\/p\u003e \u003cp\u003e13.3.3 The Combined Effect of Genes \u003ci\u003erol \u003c\/i\u003eon Secondary Metabolism 392\u003c\/p\u003e \u003cp\u003e13.4 Mechanism of Action of \u003ci\u003erol \u003c\/i\u003eGenes 393\u003c\/p\u003e \u003cp\u003e13.4.1 How \u003ci\u003erol \u003c\/i\u003eGenes Regulate ROS Production and Mediate Secondary Metabolites Production 393\u003c\/p\u003e \u003cp\u003e13.4.1.1 \u003ci\u003eAgrobacterium \u003c\/i\u003e(\u003ci\u003erol \u003c\/i\u003eGene) and ROS 393\u003c\/p\u003e \u003cp\u003e13.4.1.2 Plants Secondary Metabolism and ROS 394\u003c\/p\u003e \u003cp\u003e13.4.1.3 Stabilization of Secondary Metabolites Biosynthesis Through \u003ci\u003erol \u003c\/i\u003eGenes 395\u003c\/p\u003e \u003cp\u003e13.5 Impact of \u003ci\u003erol \u003c\/i\u003eGene on Different Secondary Metabolites 395\u003c\/p\u003e \u003cp\u003e13.5.1 Impact of \u003ci\u003erol \u003c\/i\u003eGene on Alkaliods 395\u003c\/p\u003e \u003cp\u003e13.5.2 Impact of \u003ci\u003erol \u003c\/i\u003eGenes on Flavonoids 396\u003c\/p\u003e \u003cp\u003e13.5.3 Impact of \u003ci\u003erol \u003c\/i\u003eGenes on Terpenoids 396\u003c\/p\u003e \u003cp\u003e13.6 Conclusion 397\u003c\/p\u003e \u003cp\u003eReferences 397\u003c\/p\u003e \u003cp\u003eIndex 405\u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Chemistry [\u003ca title=\"See our other books on Chemistry\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Chemistry%20%5BPN%5D%22\"\u003ePN\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Wiley-Scrivener","offers":[{"title":"Brand New","offer_id":52428639699224,"sku":"9781119640349","price":140.19,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/files\/9781119640349.jpg?v=1784682910","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/chemistry-of-biologically-potent-natural-products-and-synthetic-compounds-hardback-9781119640349","provider":"Freshly Printed Books","version":"1.0","type":"link"}