{"product_id":"cellular-aging-and-cell-death-paperback-softback-9780471121237","title":"Cellular Aging and Cell Death (Paperback \/ softback) 9780471121237","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eCellular Aging and Cell Death\u003c\/font\u003e\u003cbr\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003c\/p\u003e\n\u003cp\u003e\u003cfont size=\"4\"\u003eNikki J. Holbrook (Edited by), George R. Martin (Edited by), Richard A. Lockshin (Edited by)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780471121237, Wiley\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003ePaperback \/ softback, published 16 January 1996\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e336 pages\u003cbr\u003e26 x 18.4 x 2.1 cm, 0.822 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003eCellular AGING AND CELL DEATH\u003cbr\u003e \u003cbr\u003e Edited by Nikki J. Holbrook, George R. Martin, and Richard A.Lockshin\u003cbr\u003e \u003cbr\u003e Cellular Aging and Cell Death provides a thorough understanding ofthe mechanisms responsible for cellular aging, covering the recentresearch on programmed cell death and senescence, and describingtheir role in the control of cell proliferation and the agingprocess. This one-of-a-kind book is the first to combine the twohottest research areas of cell biology into one comprehensivetext.\u003cbr\u003e \u003cbr\u003e Leading experts contribute to give readers an authoritativeoverview of the distinct fields of cellular aging and programmedcell death, as well as to demonstrate how both fields are criticalto understanding the aging process. They address the large andgrowing interest in apoptosis, especially with regard to themolecular signals that induce and regulate programmed cell death,and the role of apoptosis in a variety of age-associated diseasesand disabilities. Throughout the book, a strong emphasis is placedon the interrelationship of the molecular, cellular, andphysiological aspects of senescence.\u003cbr\u003e \u003cbr\u003e Individual chapters discuss such topics as the role and regulationof apoptosis in development, the potential impact of cell death onsuch postmitotic tissues as nerve and muscle, and suggest thatprogrammed cell death plays an important role in both pathologicaland nonpathological aspects of aging, including neurodegenerativediseases.\u003cbr\u003e \u003cbr\u003e One important chapter focuses on the most recent research involvingthe study of telomeres, whose reduction in length with age and celldivision may underlie cellular senescence. The subject of neuronalcell death is also put into the perspective of aging.\u003cbr\u003e \u003cbr\u003e Cellular Aging and Cell Death bridges the rapidly growing fields ofcellular aging and programmed cell death. This thorough, yetconcise book will be of particular interest to graduate studentsand researchers within the fields of cell and developmentalbiology, neurobiology, immunology, and physiology. Physicians andmedical students involved in the fields of gerontology andpathology will also find this an informative reference.\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003ePartial table of contents:\u003cbr\u003e \u003cbr\u003e BASIC MECHANISMS OF AGING.\u003cbr\u003e \u003cbr\u003e Genetics of Aging and Longevity in Lower Organisms (T. Johnson, etal.).\u003cbr\u003e \u003cbr\u003e Mitochondrial DNA Mutations and Aging (E. Schon, et al.).\u003cbr\u003e \u003cbr\u003e Protein Damage and Oxidative Stress (T. Tabatabaie \u0026amp; R.Floyd).\u003cbr\u003e \u003cbr\u003e MOLECULAR MECHANISMS CONTROLLING CELLULAR SENESCENCE.\u003cbr\u003e \u003cbr\u003e Molecular Genetics of In Vitro Cellular Senescence (C. Afshari\u0026amp; J. Barrett).\u003cbr\u003e \u003cbr\u003e Mechanisms of Escaping Senescence in Human Diploid Cells (W. Wright\u0026amp; J. Shay).\u003cbr\u003e \u003cbr\u003e PROGRAMMED CELL DEATH: MECHANISMS AND ROLE IN DEVELOPMENT, AGINGAND DISEASE.\u003cbr\u003e \u003cbr\u003e The Biology of Cell Death and Its Relationship to Aging (R.Lockshin \u0026amp; Z. Zakeri).\u003cbr\u003e \u003cbr\u003e Programmed Cell Death During Development of Animals (C. Milligan\u0026amp; L. Schwartz).\u003cbr\u003e \u003cbr\u003e Neuronal Loss in Aging and Disease (B. Wolozin, et al.).\u003cbr\u003e \u003cbr\u003e Index.\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Biology, life sciences [\u003ca title=\"See our other books on Biology, life sciences\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Biology,%20life%20sciences%20%5BPS%5D%22\"\u003ePS\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Wiley-Liss","offers":[{"title":"Brand New","offer_id":52501440135448,"sku":"9780471121237","price":210.19,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/files\/9780471121237.jpg?v=1786239038","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/cellular-aging-and-cell-death-paperback-softback-9780471121237","provider":"Freshly Printed Books","version":"1.0","type":"link"}