{"product_id":"cell-death-hardback-9780470715734","title":"Cell Death (Hardback) 9780470715734","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eCell Death\u003c\/font\u003e\u003cbr\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003c\/p\u003e\n\u003cp\u003e\u003cfont size=\"4\"\u003eGerry Melino (Edited by), G Melino (Author), David Vaux (Edited by)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780470715734, Wiley\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 28 January 2010\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e316 pages\u003cbr\u003e25.5 x 19.4 x 2.2 cm, 0.964 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cem\u003e\u003cfont size=\"3\"\u003e\"The book of Melino and Vaux is definitively a tremendous effort to summarize the vast amount of knowledge. It is divided into 29 chapters, which are all written by the leading experts in the field. Chapters range from basic biochemical mechanisms to therapy, from apoptosis to autophagy and from lower organisms to humans, and as such give a great overview of the research area.\" (\u003ci\u003eCell Death and Differentiation\u003c\/i\u003e, December 2010)\u003cbr\u003e \u003cbr\u003e  \"Each chapter contains novel information ensuring that this book stands out among the numerous others centered on cell death and constitutes an extremely useful addition.\" (\u003ci\u003eCell Death and Disease\u003c\/i\u003e, December 2010)\u003c\/font\u003e\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003eThis book on cell death contains 29 self-contained, peer-reviewed articles written by leading scientists in each field. It features overview articles aimed at undergraduates and non-specialists, which present basic information and provide entry into the following advanced articles. These advanced articles are written for postgraduate students and research workers, containing detailed information and key references allowing the reader to investigate a specific area in more depth. The book is an essential resource for educational purposes as well as a reference work for experienced researchers in the field. The articles will also be available electronically as part of the acclaimed \u003ci\u003eEncyclopedia of Life Sciences (ELS)\u003c\/i\u003e. \u003cp\u003e\u003cb\u003eKey features:\u003c\/b\u003e\u003c\/p\u003e \u003cul\u003e \u003cli\u003eProvides a comprehensive overview on the research of programmed cell death.\u003c\/li\u003e \u003cli\u003eEdited by leaders in the field.\u003c\/li\u003e \u003cli\u003eClearly written and illustrated articles.\u003c\/li\u003e \u003cli\u003eFull colour throughout.\u003c\/li\u003e \u003cli\u003eA spin-on to the acclaimed reference work, the \u003ci\u003eEncyclopedia of Life Science (ELS).\u003c\/i\u003e\n\u003c\/li\u003e \u003cli\u003eCombines introductory information with coverage of the latest discoveries in the field.\u003c\/li\u003e \u003cli\u003eFeatures overview level articles for advanced students or people new to a topic and more advanced articles for those requiring more detailed information.\u003c\/li\u003e \u003cli\u003eServes as a reference work for advanced students as well as researchers in this field.\u003c\/li\u003e \u003cli\u003eIdeal library purchase for science, medical, and technology libraries in academia, government, and industry; medical libraries; networks and consortia covering these markets.\u003c\/li\u003e \u003c\/ul\u003e\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eContributors.  \u003cp\u003ePreface.\u003c\/p\u003e \u003cp\u003eThe Siren’s Song: This Death That Makes Life Live (\u003ci\u003eGerry Melino, Richard A Knight and Jean-Claude Ameisen).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eThe Origin and Evolution of Programmed Cell Death (\u003ci\u003eJean Claude Ameisen).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eCell Death in C. elegans (\u003ci\u003eAtaman Sendoel and Michael O Hengartner).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eCaspases and Cell Death (\u003ci\u003eLorraine D Hernandez, Caroline Houde, Maarten Hoek, Brent Butts, Donald W Nicholson and Huseyin Mehmet).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eThe Apoptosome: The Executioner of Mitochondria-mediated Apoptosis (\u003ci\u003eElisabetta Ferraro and Francesco Cecconi).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eCaspases, Substrates and Sequential Activation (\u003ci\u003eJohn G Walsh and Seamus J Martin).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eDismantling the Apoptotic Cell (\u003ci\u003ePaula Deming and Sally Kornbluth).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eThe BCL-2 Family Proteins – Key Regulators and Effectors of Apoptosis (\u003ci\u003eDavid L Vaux).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eBH3-only Proteins (\u003ci\u003eLina Happo, Andreas Strasser and Clare L Scott).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eMitochondrial Outer Membrane Permeabilization (\u003ci\u003eMelissa J Parsons and Douglas R Green).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eMitochondria Fusion and Fission (\u003ci\u003eGiovanni Benard, Guihong Peng and Mariusz Karbowski).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eDeath Receptors (\u003ci\u003ePeter H Krammer and Inna N Lavrik).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eDeath Receptors at the Molecular Level: Therapeutic Implications (\u003ci\u003eMarion MacFarlane).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eDeath Receptor-induced Necroptosis (\u003ci\u003eWim Declercq, Franky Van Herreweghe, Tom Vanden Berghe and Peter Vandenabeele).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eInhibitor of Apoptosis (IAP) and BIR-containing Proteins (\u003ci\u003eDavid L Vaux).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eStructures, Domains and Functions in Cell Death (DD, DED, CARD, PYD) (\u003ci\u003eHao Wu and Yu-Chih Lo).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eStructure and Function of IAP and Bcl-2 Proteins (\u003ci\u003eMark G Hinds, Peter D Mace and Catherine L Day).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eEngulfment of Apoptotic Cells and its Physiological Roles (\u003ci\u003eRikinari Hanayama, Masanori Miyanishi, Hiroshi Yamaguchi, Jun Suzuki and Shigekazu Nagata).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eAutophagy (\u003ci\u003eMaría Isabel Colombo and Hans-Uwe Simon).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eAutophagy in Nonmammalian Systems (\u003ci\u003eJahda H Hill and Eric H Baehrecke).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eApoptosis: Regulatory Genes and Disease (\u003ci\u003eJames E Vince and John Silke).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eCaspases in Inflammation and Immunity (\u003ci\u003ePhilippe M LeBlanc and Maya Saleh).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eImmunity, Granzymes and Cell Killing (\u003ci\u003eNigel J Waterhouse, Olivia Susanto, Karin A Sedelies and Joseph A Trapani).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eP53 and Cell Death (\u003ci\u003eKamil Wolyniec, Sue Haupt and Ygal Haupt).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eCornification of the Skin: A Non-apoptotic Cell Death Mechanism (\u003ci\u003eE Candi, RA Knight and G Melino).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eApoptosis: Inherited Disorders (\u003ci\u003eHelen C Su and Michael J Lenardo).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eFrom Reactive Oxygen and Nitrogen Species to Therapy (\u003ci\u003eScott R McKercher, Tomohiro Nakamura and Stuart A Lipton).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eMicrobial Inhibitors of Apoptosis (\u003ci\u003eGeorg Häcker).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eDrug Discovery in Apoptosis (\u003ci\u003eTom O’Brien and Vishva M Dixit).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eSubject Index.\u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Biology, life sciences [\u003ca title=\"See our other books on Biology, life sciences\" 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