{"product_id":"carbohydrates-in-drug-discovery-and-development-synthesis-and-application-paperback-9780128166758","title":"Carbohydrates in Drug Discovery and Development; Synthesis and Application (Paperback) 9780128166758","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eCarbohydrates in Drug Discovery and Development\u003c\/font\u003e\u003cbr\u003e\r\n\u003cfont size=\"5\"\u003eSynthesis and Application\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cem\u003eReviews developments in synthesis biology and biomedical applications, along with the therapeutic and pharmacological aspects of carbohydrate chemistry\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eVinod K. Tiwari (Edited by)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780128166758, Elsevier Science\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003ePaperback, published 1 August 2020\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e714 pages\u003cbr\u003e22.9 x 15.1 x 4.3 cm, 1.13 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003e\u003ci\u003eCarbohydrates in Drug Discovery and Development: Synthesis and Applications\u003c\/i\u003e examines recent and notable developments in the synthesis, biology, therapeutic, and biomedical applications of carbohydrates, which is considered to be a highly promising area of research in the field of medicinal chemistry. Their role in several important biological processes, notably energy storage, transport, modulation of protein function, intercellular adhesion, malignant transformation, signal transduction, viral, and bacterial cell surface recognition formulate the carbohydrate systems to be an exceedingly considerable scaffold for the development of new chemical entities of pharmacological importance. In addition to their easy accessibility, high functionality and chiralpool characteristics are the few additional fascinating structural features of carbohydrates, which further enhance their utilities and thus they have been able to attract chemists and biologists toward harnessing these properties for the past several decades.This book covers an advanced aspect of carbohydrate-based molecular scaffolding, starting with a general introduction followed by a detailed discussion about the impact of diverse carbohydrate-containing molecules of great therapeutic values and their impact on drug discovery and development. The topics covered in this book include the significance of heparin mimetics as the possible tools for the modulation of biology and therapy, chemistry and bioactivities of C-glycosylated compounds, inositols, iminosugars, KDO, sialic acids, glycohybrids, macrocycles, plant oligosaccharides, anti-bacterial and anti-cancer vaccines, antibiotics, and more.\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e1. Recent trends and challenges on carbohydrate-based molecular scaffolding: general consideration toward impact of carbohydrates in drug discovery and development\u003cbr\u003e2. Heparin mimetics as tools for modulation of biology and therapy\u003cbr\u003e3. Bioactive C-glycosides inspired from natural products toward therapeutics\u003cbr\u003e4. 3-Deoxy-d-manno-oct-2-ulosonic acid (Kdo) derivatives in antibacterial drug discovery\u003cbr\u003e5. Sialic acid-containing molecules in drug discovery and development\u003cbr\u003e6. Glycan microarray: Toward drug discovery and development\u003cbr\u003e7. Recent developments in the synthesis of biologically relevant Iinositol derivatives\u003cbr\u003e8. Iminosugars in medicinal chemistry\u003cbr\u003e9. Carbohydrate-protein interactions: Enhancing multivalency effects through statistical rebinding\u003cbr\u003e10. Carbo-click in drug discovery and development: Opportunity and challenges\u003cbr\u003e11. Glycohybrids molecule in medicinal chemistry: Present status and future prospective\u003cbr\u003e12. Biologically active carbohydrate-containing macrocycles\u003cbr\u003e13. Carbohydrate-based antibiotics: Opportunities and challenges\u003cbr\u003e14. Carbohydrate-based anti-bacterial and anti-cancer vaccines\u003cbr\u003e15. Opportunity of plant oligosaccharides and polysaccharides in drug development\u003cbr\u003e16. N-acetylgalactosamine (GalNAc)-conjugates: Delivering oligonucleotide drugs to the liver\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Organic chemistry [\u003ca title=\"See our other books on Organic chemistry\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Organic%20chemistry%20%5BPNN%5D%22\"\u003ePNN\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Elsevier","offers":[{"title":"Default Title","offer_id":46649073369368,"sku":"9780128166758","price":151.29,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/products\/9780128166758.jpg?v=1694097003","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/carbohydrates-in-drug-discovery-and-development-synthesis-and-application-paperback-9780128166758","provider":"Freshly Printed Books","version":"1.0","type":"link"}