{"product_id":"cancer-and-noncoding-rnas-hardback-9780128110225","title":"Cancer and Noncoding RNAs (Hardback) 9780128110225","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eCancer and Noncoding RNAs\u003c\/font\u003e\u003cbr\u003e\r\n\r\n\r\n\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cp\u003eProvides a holistic analysis of the role of noncoding RNAs in regulating complex human disease by epigenetic means, with an emphasis on cancer\u003c\/p\u003e\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eJayprokas Chakrabarti (Edited by), Sanga Mitra (Edited by), Trygve Tollefsbol (Series edited by)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780128110225, Elsevier Science\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 2 October 2017\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e576 pages\u003cbr\u003e23.4 x 19 x 3.3 cm, 1.38 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003e\u003cp\u003e\u003ci\u003eCancer and Noncoding RNAs\u003c\/i\u003e offers an in-depth exploration of noncoding RNAs and their role in epigenetic regulation of complex human disease, most notably cancer. In addition to examining microRNAs, this volume provides a unique evaluation of more recently profiled noncoding RNAs now implicated in carcinogenesis, including lncRNAs, piRNAs, circRNAs, and tRNAs, identifying differences in function between these noncoding RNAs and how they interact with the rest of the epigenome. A broad range of chapters from experts in the field detail epigenetic regulation of various cancer types, along with recent next generation sequencing technologies, genome-wide association studies (GWAS) and bioinformatics approaches. \u003c\/p\u003e  \u003cp\u003eThis book will help researchers in genomic medicine and cancer biology better understand the role of noncoding RNAs in epigenetics, aiding in the development of useful biomarkers for diagnosis, prognosis and new RNA-based disease therapies.\u003c\/p\u003e\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e\u003cp\u003e1. Introduction\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSECTION I: NON-CODING RNAs: FINE-TUNING CANCER \u003c\/b\u003e2. miRNA and Cancer: A Deadly Liaison? 3. Alteration of MicroRNA Biogenesis Pathways in Cancers 4. MicroRNAs In Exosomes in Cancer 5. Circulating miRNAs Incresaing the Risk of Cancer 6.  Long Noncoding RNAs as Cancer Biomarkers 7. The Balancing Act: Understanding MicroRNA and Competing Endogenous RNA Regulation in Cancer 8. PIWI-Interacting RNAs (piRNAs) and Cancer 9. Transfer RNA in Cancer 10. Dynamic Regulation of tRNA Modifications in Cancer 11. Circular RNA: A Novel Noncoding RNA in Cancer 12. Antisense RNA and Cancer 13. Implication of Other Noncoding RNAs in Cancer\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSECTION 2: GENETIC DYSREGULATION OF NON-CODING RNA IN CANCER \u003c\/b\u003e14. Noncoding RNA Alterations in Cancer Molecular Pathways 15. Genetic Alteration of MicroRNA Affecting Cancer Pathways 16. Genetic Variations of Long Noncoding RNAs in Cancer\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSECTION 3: EPIGENETIC EFFECT ON CANCER THROUGH NON-CODING RNAs \u003c\/b\u003e17. Cross Talk Between Noncoding RNAs and DNA Methylation and Demethylation in Cancer 18. Noncoding RNAs Act as a Chromatin Scaffold of Histone Modification Complexes in Cancer 19. Heterochromatin Modulation and PcG Control of Gene Expression Medicated by Noncoding RNA in Cancer 20. Epigenetic Control of MicroRNA Expression and Cancer 21. Implications of Long Noncoding RNAs in Cancer Epigenetics\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSECTION 4: THERAPEUTIC IMPLICATIONS OF NON-CODING RNA IN CANCER \u003c\/b\u003e22. Long Noncoding RNAs: Insight Into Their Roles in Normal and Cancer Stem Cells 23. Clinical Relevance, Prognostic Potential, and Therapeutic Strategies of Noncoding RNAs in Cancer 24. Noncoding RNAs: Novel Targets in Anticancer Drug Development\u003c\/p\u003e \u003cp\u003e\u003cb\u003eSECTION 5: BIOINFORMATICS' DETECTION OF NON-CODING RNA IN CANCER \u003c\/b\u003e25. Cancer Noncoding RNA Discovery Through High-Throughput Sequencing 26. Noncoding RNAs as a Cauce of Cancer: Evidence From Genome-Wide Association Studies and Reverse Genetics 27. A Comparative Evaluation of Emerging Databases and Tools for Cancer Noncoding RNAs 28. Future Directions and Challenges Involved in Cancer Noncoding RNomics\u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Genetic engineering [\u003ca title=\"See our other books on Genetic engineering\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Genetic%20engineering%20%5BTCBG%5D%22\"\u003eTCBG\u003c\/a\u003e], Medical genetics [\u003ca title=\"See our other books on Medical genetics\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Medical%20genetics%20%5BMFN%5D%22\"\u003eMFN\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Academic Press","offers":[{"title":"Default Title","offer_id":46649765134616,"sku":"9780128110225","price":120.99,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/products\/9780128110225.jpg?v=1694103368","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/cancer-and-noncoding-rnas-hardback-9780128110225","provider":"Freshly Printed Books","version":"1.0","type":"link"}