{"product_id":"biomechanics-and-cells-hardback-9780521454544","title":"Biomechanics and Cells (Hardback) 9780521454544","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eBiomechanics and Cells\u003c\/font\u003e\u003cbr\u003e\r\n\r\n\r\n\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eThis volume describes how mechanical forces interact with a range of living tissue-types at the level of the cell.\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eFiona Lyall (Edited by), A. J. El Haj (Edited by)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780521454544, Cambridge University Press\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 28 April 1994\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e288 pages, 75 b\/w illus.  5 tables\u003cbr\u003e22.9 x 15.2 x 2.1 cm, 0.59 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cem\u003e\u003cfont size=\"3\"\u003e\"The strengths of this book include the diversity of cell types and physiological responses covered, the significant detail on the putative biological mechanisms by which mechanical stimuli may be transduced by cells, and most of all the variety and detail of the experimental models, preparations, and devices that are described...an interesting collection of articles on mechanical signal transduction by cells in a variety of experimental settings.\"  A.D. McCulloch, Applied Mechanics Review\u003c\/font\u003e\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003eAlthough the effects of exercise and mechanical forces on musculoskeletal and cardiovascular systems have been well documented, the actual mechanisms by which mechanical forces act at the cellular level are not well understood. At present, studies of the interaction of mechanical forces with cells encompass many different cell types in various tissues. This volume draws together these apparently disparate observations and makes comparisons between the nature of cellular responses in different tissues. Studies of cells derived from skeletal muscle, bone and cardiovascular tissue are considered to provide a comprehensive synthesis and review of recent work. The volume will be of interest to all those working in musculoskeletal and cardiovascular biology, as well as those taking courses in exercise and sport science, biomechanics and orthopaedics.\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003ePreface\u003cbr\u003e Part I. Soft Tissue: 1. Signal transduction in vascular cells exposed to cyclic strain\u003cbr\u003e 2. Effects of pressure overload on vascular smooth muscle cells\u003cbr\u003e 3. Effect of increased flow on release of vasoactive substances from vascular endothelial cells\u003cbr\u003e 4. Modulation of endothelium derived relaxing factor activity by flow\u003cbr\u003e 5. Stretch, overload and gene expression in muscle\u003cbr\u003e 6. Stretch sensitivity in stretch receptor muscles\u003cbr\u003e 7. Mechanical interactions with plant cells - a selective overview\u003cbr\u003e 8. Mechanical tensing of cells and chromosome arrangement\u003cbr\u003e 9. Alterations in gene expression induced by low-frequency, low-intensity electromagnetic fields\u003cbr\u003e Part II. Hard Tissue: 10. Cellular modelling of mechanical interactions with the skeleton\u003cbr\u003e 11. Mechanical and hormonal influences in vivo cause regional differences in bone remodelling\u003cbr\u003e 12. Mechanically sensitive cells in bone\u003cbr\u003e 13. Mechanical stress and bone development\u003cbr\u003e 14. Applications of homogenous, defined strains to cell cultures\u003cbr\u003e 15. The role of prostaglandin in bone cells as mediators of mechanical strain\u003cbr\u003e 16. Effects of mechanical stretch on actin polymerisation in fibroblasts of the periodontium\u003cbr\u003e 17. Modulation of cartilage extracellular matrix turnover by pulsed electromagnetic fields\u003cbr\u003e Index.\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Cellular biology [\u003ca title=\"See our other books on Cellular biology\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Cellular%20biology%20%5Bcytology%5D%20%5BPSF%5D%22\"\u003ecytology PSF\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Cambridge University Press","offers":[{"title":"Default Title","offer_id":46007507583256,"sku":"9780521454544","price":89.68,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/products\/9780521454544i_26d574c1-309e-44ac-b82a-90556d4e6910.jpg?v=1691382287","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/biomechanics-and-cells-hardback-9780521454544","provider":"Freshly Printed Books","version":"1.0","type":"link"}