{"product_id":"biomaterials-from-nature-for-advanced-devices-and-therapies-hardback-9781118478059","title":"Biomaterials from Nature for Advanced Devices and Therapies (Hardback) 9781118478059","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eBiomaterials from Nature for Advanced Devices and Therapies\u003c\/font\u003e\u003cbr\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003c\/p\u003e\n\u003cp\u003e\u003cfont size=\"4\"\u003eNuno M. Neves (Edited by), N Neves (Author), Rui L. Reis (Edited by)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9781118478059, Wiley\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 29 November 2016\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e704 pages\u003cbr\u003e23.9 x 15.8 x 3.8 cm, 1.134 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003e\u003cp\u003eIn-depth information on natural biomaterials and their applications for translational medicine!\u003c\/p\u003e \u003cul\u003e \u003cli\u003eUndiluted expertise: edited by world-leading experts with contributions from top-notch international scientists, collating experience and cutting-edge knowledge on natural biomaterials from all over the world\u003c\/li\u003e \u003cli\u003eA must-have on the shelf in every biomaterials lab: graduate and PhD students beginning their career in biomaterials science and experienced researchers and practitioners alike will turn to this comprehensive reference in their daily work\u003c\/li\u003e \u003cli\u003eLink to clinical practice: chapters on translational research make readers aware of what needs to be considered when a biomaterial leaves the lab to be routinely used\u003c\/li\u003e \u003c\/ul\u003e\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e\u003cp\u003eCONTRIBUTORS xix\u003c\/p\u003e \u003cp\u003ePREFACE xxix\u003c\/p\u003e \u003cp\u003e\u003cb\u003ePART I 1 Collagen-Based Porous Scaffolds for Tissue Engineering 3\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eGuoping Chen and Naoki Kawazoe\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e1.1 Introduction, 3\u003c\/p\u003e \u003cp\u003e1.2 Collagen Sponges, 4\u003c\/p\u003e \u003cp\u003e1.3 Collagen Sponges with Micropatterned Pore Structures, 7\u003c\/p\u003e \u003cp\u003e1.4 Collagen Sponges with Controlled Bulk Structures, 10\u003c\/p\u003e \u003cp\u003e1.5 Hybrid Scaffolds, 12\u003c\/p\u003e \u003cp\u003e1.6 Conclusions, 13\u003c\/p\u003e \u003cp\u003eReferences, 14\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 Marine Collagen Isolation and Processing Envisaging Biomedical Applications 16\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eJoana Moreira-Silva, Gabriela S. Diogo, Ana L. P. Marques, Tiago H. Silva, and Rui L. Reis\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2.1 Introduction, 16\u003c\/p\u003e \u003cp\u003e2.2 Extraction of Collagen from Marine Sources, 18\u003c\/p\u003e \u003cp\u003e2.3 Collagen Characterization, 22\u003c\/p\u003e \u003cp\u003e2.4 Marine Collagen Wide Applications, 25\u003c\/p\u003e \u003cp\u003e2.5 Final Remarks, 32\u003c\/p\u003e \u003cp\u003eAcknowledgements, 34\u003c\/p\u003e \u003cp\u003eReferences, 34\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Gelatin-Based Biomaterials for Tissue Engineering and Stem Cell Bioengineering 37\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eMehdi Nikkhah, Mohsen Akbari, Arghya Paul, Adnan Memic, Alireza Dolatshahi-Pirouz, and Ali Khademhosseini\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3.1 Introduction, 37\u003c\/p\u003e \u003cp\u003e3.2 Crosslinking of Gelatin, 38\u003c\/p\u003e \u003cp\u003e3.3 Physical Properties of Gelatin, 39\u003c\/p\u003e \u003cp\u003e3.4 Application of Gelatin-Based Biomaterials in Tissue Engineering, 40\u003c\/p\u003e \u003cp\u003e3.5 Gelatin for Stem Cell Therapy, 45\u003c\/p\u003e \u003cp\u003e3.6 Application of Gelatin in Delivery Systems, 49\u003c\/p\u003e \u003cp\u003e3.7 Conclusion and Perspectives, 50\u003c\/p\u003e \u003cp\u003eAcknowledgements, 50\u003c\/p\u003e \u003cp\u003eAbbreviations, 50\u003c\/p\u003e \u003cp\u003eReferences, 51\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Hyaluronic Acid-Based Hydrogels on a Micro and Macro Scale 63\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eA. Borzacchiello, L. Russo, and L. Ambrosio\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4.1 Classification and Structure of Hydrogels, 63\u003c\/p\u003e \u003cp\u003e4.2 Hyaluronic Acid, 65\u003c\/p\u003e \u003cp\u003e4.3 Hydrogel Mechanical Properties, 66\u003c\/p\u003e \u003cp\u003e4.4 HA-Based Hydrogel for Biomedical Applications, 70\u003c\/p\u003e \u003cp\u003eReferences, 75\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Chondroitin Sulfate as a Bioactive Macromolecule for Advanced Biological Applications and Therapies 79\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eNicola Volpi\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5.1 CS Structure, 81\u003c\/p\u003e \u003cp\u003e5.2 Biological Roles of CS, 81\u003c\/p\u003e \u003cp\u003e5.3 Osteoarthritis Treatment, 84\u003c\/p\u003e \u003cp\u003e5.4 Cardio-Cerebrovascular Disease, 84\u003c\/p\u003e \u003cp\u003e5.5 Tissue Regeneration and Engineering, 85\u003c\/p\u003e \u003cp\u003e5.6 Chondroitin Sulfate-Polymer Conjugates, 86\u003c\/p\u003e \u003cp\u003e5.7 Conclusions and Future Perspectives, 87\u003c\/p\u003e \u003cp\u003eReferences, 88\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 Keratin 93\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eMark Van Dyke\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6.1 Introduction, 93\u003c\/p\u003e \u003cp\u003e6.2 Preparation of Keratoses, 98\u003c\/p\u003e \u003cp\u003e6.3 Preparation of Kerateines, 100\u003c\/p\u003e \u003cp\u003e6.4 Oxidative Sulfitolysis, 101\u003c\/p\u003e \u003cp\u003e6.5 Summary, 102\u003c\/p\u003e \u003cp\u003eReferences, 102\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 Elastin-Like Polypeptides: Bio-Inspired Smart Polymers for Protein Purification, Drug Delivery and Tissue Engineering 106\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eJayanta Bhattacharyya, Joseph J. Bellucci, and Ashutosh Chilkoti\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7.1 Introduction, 106\u003c\/p\u003e \u003cp\u003e7.2 Recombinant Protein Production Using ELPs as Purification Tags, 107\u003c\/p\u003e \u003cp\u003e7.3 Delivery of Therapeutics with ELPs, 113\u003c\/p\u003e \u003cp\u003e7.4 Tissue Engineering with ELPs, 119\u003c\/p\u003e \u003cp\u003e7.5 Conclusions, 122\u003c\/p\u003e \u003cp\u003eAcknowledgements, 122\u003c\/p\u003e \u003cp\u003eAbbreviations, 122\u003c\/p\u003e \u003cp\u003eReferences, 123\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 Silk: A Unique Family of Biopolymers 127\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eA. Motta, M. Floren, and C. Migliaresi\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8.1 Introduction, 127\u003c\/p\u003e \u003cp\u003e8.2 Main Silk Polymers, 129\u003c\/p\u003e \u003cp\u003e8.3 Fibroin Basic Processing: Regenerated Silk Fibroin, 131\u003c\/p\u003e \u003cp\u003e8.4 Materials Fabrication of Silk Proteins, 131\u003c\/p\u003e \u003cp\u003e8.5 Advanced Material Applications of Silks, 135\u003c\/p\u003e \u003cp\u003e8.6 Conclusion, 136\u003c\/p\u003e \u003cp\u003eReferences, 137\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 Silk Protein Sericin: Promising Biopolymer for Biological and Biomedical Applications 142\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eSunita Nayak and Subhas C. Kundu\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9.1 Introduction, 142\u003c\/p\u003e \u003cp\u003e9.2 Sericin Extraction and Processing, 146\u003c\/p\u003e \u003cp\u003e9.3 Potential Applications of Sericin, 147\u003c\/p\u003e \u003cp\u003e9.4 Immunogenicity and Toxicity of Sericin, 152\u003c\/p\u003e \u003cp\u003e9.5 Conclusion, 153\u003c\/p\u003e \u003cp\u003eAcknowledgements, 154\u003c\/p\u003e \u003cp\u003eReferences, 154\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 Fibrin 159\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eMarkus Kerbl, Philipp Heher, James Ferguson, and Heinz Redl\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10.1 Introduction, 159\u003c\/p\u003e \u003cp\u003e10.2 Fibrin Clotting, 160\u003c\/p\u003e \u003cp\u003e10.3 Fibrin Degradation, 160\u003c\/p\u003e \u003cp\u003e10.4 Fibrin Glue, 163\u003c\/p\u003e \u003cp\u003e10.5 Conclusion, 170\u003c\/p\u003e \u003cp\u003eAcknowledgement, 171\u003c\/p\u003e \u003cp\u003eReferences, 171\u003c\/p\u003e \u003cp\u003e\u003cb\u003e11 Casein Proteins 176\u003c\/b\u003e\u003cbr\u003e\u003ci\u003ePranav K. Singh and Harjinder Singh\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e11.1 Introduction, 176\u003c\/p\u003e \u003cp\u003e11.2 Structures and Properties of Casein, 178\u003c\/p\u003e \u003cp\u003e11.3 Interaction of Caseins with Metal Ions, 184\u003c\/p\u003e \u003cp\u003e11.4 Conclusions, 185\u003c\/p\u003e \u003cp\u003eReferences, 186\u003c\/p\u003e \u003cp\u003e\u003cb\u003e12 Biomaterials from Decellularized Tissues 190\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eRicardo Londono and Stephen F. Badylak\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e12.1 Introduction, 190\u003c\/p\u003e \u003cp\u003e12.2 Host Response to Implanted ECM-Derived Biomaterials, 196\u003c\/p\u003e \u003cp\u003eReferences, 199\u003c\/p\u003e \u003cp\u003e\u003cb\u003e13 Demineralized Bone Matrix: A Morphogenetic Extracellular Matrix 211\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eA. Hari Reddi and Ryosuke Sakata\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e13.1 Introduction, 211\u003c\/p\u003e \u003cp\u003e13.2 Demineralized Bone Matrix (DBM), 211\u003c\/p\u003e \u003cp\u003e13.3 From DBM to Bone Morphogenetic Proteins (BMPs), 213\u003c\/p\u003e \u003cp\u003e13.4 BMPs Bind to Extracellular Matrix, 216\u003c\/p\u003e \u003cp\u003e13.5 BMP Receptors, 216\u003c\/p\u003e \u003cp\u003e13.6 Future Perspectives, 218\u003c\/p\u003e \u003cp\u003eAcknowledgements, 218\u003c\/p\u003e \u003cp\u003eReferences, 218\u003c\/p\u003e \u003cp\u003ePART II\u003c\/p\u003e \u003cp\u003e\u003cb\u003e14 Recent Developments on Chitosan Applications in Regenerative Medicine 223\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eAna Rita C. Duarte, Vitor M. Correlo, Joaquim M. Oliveira, and Rui L. Reis\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e14.1 Introduction, 223\u003c\/p\u003e \u003cp\u003e14.2 Chitosan and Derivatives, 224\u003c\/p\u003e \u003cp\u003e14.3 Regenerative Medicine Applications of Chitosan, 227\u003c\/p\u003e \u003cp\u003e14.4 Processing Methodologies, 231\u003c\/p\u003e \u003cp\u003e14.5 Final Remarks, 236\u003c\/p\u003e \u003cp\u003eAcknowledgments, 237\u003c\/p\u003e \u003cp\u003eReferences, 237\u003c\/p\u003e \u003cp\u003e\u003cb\u003e15 Starch-Based Blends in Tissue Engineering 244\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eP.P. Carvalho, M.T. Rodrigues, R.L. Reis, and M.E. Gomes\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e15.1 Introduction, 244\u003c\/p\u003e \u003cp\u003e15.2 Starch, 245\u003c\/p\u003e \u003cp\u003e15.3 Modification of Starch for Biomedical Applications, 247\u003c\/p\u003e \u003cp\u003e15.4 Starch-Based Blends, 248\u003c\/p\u003e \u003cp\u003e15.5 Conclusions and Future Perspectives, 254\u003c\/p\u003e \u003cp\u003eReferences, 255\u003c\/p\u003e \u003cp\u003e\u003cb\u003e16 Agarose Hydrogel Characterization for Regenerative Medicine Applications: Focus on Engineering Cartilage 258\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eBrendan L. Roach, Adam B. Nover, Gerard A. Ateshian, and Clark T. Hung\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e16.1 The Foundations of Agarose, 258\u003c\/p\u003e \u003cp\u003e16.2 Structure-Function Relationships of Agarose Hydrogels, 259\u003c\/p\u003e \u003cp\u003e16.3 Agarose as a Tissue Engineering Scaffold, 261\u003c\/p\u003e \u003cp\u003e16.4 Agarose in the Clinic, 266\u003c\/p\u003e \u003cp\u003e16.5 A Scaffold to Build On, 267\u003c\/p\u003e \u003cp\u003eAcknowledgements, 268\u003c\/p\u003e \u003cp\u003eReferences, 268\u003c\/p\u003e \u003cp\u003e\u003cb\u003e17 Bioengineering Alginate for Regenerative Medicine Applications 274\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eEmil Ruvinov and Smadar Cohen\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e17.1 Introduction, 274\u003c\/p\u003e \u003cp\u003e17.2 Regenerative Medicine: Definition and Strategies, 275\u003c\/p\u003e \u003cp\u003e17.3 Alginate Biomaterial, 277\u003c\/p\u003e \u003cp\u003e17.4 Alginate Implant: First in Man Trial for Prevention of Heart Failure, 281\u003c\/p\u003e \u003cp\u003e17.5 Alginate Hydrogel as a Vehicle for Stem Cell Delivery and Retention, 284\u003c\/p\u003e \u003cp\u003e17.6 Engineering Alginate-Based Cell Microenvironments, 287\u003c\/p\u003e \u003cp\u003e17.7 Alginate Hydrogel Carrier for Growth Factor Delivery, 289\u003c\/p\u003e \u003cp\u003e17.8 Engineering Alginate for Affinity Binding and Presentation of Heparin-Binding Growth Factors, 292\u003c\/p\u003e \u003cp\u003eReferences, 300\u003c\/p\u003e \u003cp\u003e\u003cb\u003e18 Dextran 307\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eRong Wang, Pieter J. Dijkstra, and Marcel Karperien\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e18.1 Introduction, 307\u003c\/p\u003e \u003cp\u003e18.2 Structure and Properties, 308\u003c\/p\u003e \u003cp\u003e18.3 Dextran Derivatives, 310\u003c\/p\u003e \u003cp\u003e18.4 Dextran Copolymers, 314\u003c\/p\u003e \u003cp\u003e18.5 Degradation, 316\u003c\/p\u003e \u003cp\u003e18.6 Outlook, 316\u003c\/p\u003e \u003cp\u003eReferences, 316\u003c\/p\u003e \u003cp\u003e\u003cb\u003e19 Gellan Gum-based Hydrogels for Tissue Engineering Applications 320\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eJoana Silva-Correia, Joaquim Miguel Oliveira, and Rui Lu´ýs Reis\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e19.1 Introduction, 320\u003c\/p\u003e \u003cp\u003e19.2 Gellan Gum and its Derivatives, 322\u003c\/p\u003e \u003cp\u003e19.3 Tissue Engineering Applications, 325\u003c\/p\u003e \u003cp\u003e19.4 Final Remarks, 331\u003c\/p\u003e \u003cp\u003eAcknowledgments, 332\u003c\/p\u003e \u003cp\u003eReferences, 332\u003c\/p\u003e \u003cp\u003ePART III\u003c\/p\u003e \u003cp\u003e\u003cb\u003e20 Biomedical Applications of Polyhydroxyalkanoates 339\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eL.R. Lizarraga-Valderrama, B. Panchal, C. Thomas, A.R. Boccaccini, and I. Roy\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e20.1 Introduction, 339\u003c\/p\u003e \u003cp\u003e20.2 Skin Tissue Engineering, 341\u003c\/p\u003e \u003cp\u003e20.3 Nerve Tissue Engineering, 344\u003c\/p\u003e \u003cp\u003e20.4 Cardiac Tissue Engineering, 348\u003c\/p\u003e \u003cp\u003e20.5 Dental Tissue Engineering, 356\u003c\/p\u003e \u003cp\u003e20.6 Bone Tissue Engineering, 358\u003c\/p\u003e \u003cp\u003e20.7 Cartilage Tissue Engineering, 366\u003c\/p\u003e \u003cp\u003e20.8 Osteochondral Tissue Engineering, 368\u003c\/p\u003e \u003cp\u003e20.9 Drug Delivery, 370\u003c\/p\u003e \u003cp\u003e20.10 Conclusions and the Future Potential of PHAs in Biomedical Applications, 373\u003c\/p\u003e \u003cp\u003eReferences, 373\u003c\/p\u003e \u003cp\u003e\u003cb\u003e21 Bacterial Cellulose 384\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eHernane S. Barud, Junkal Gutierrez, Wilton R. Lustri, Maristela F.S. Peres, Sidney J.L. Ribeiro, Sybele Saska, and Agniezska Tercjak\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e21.1 Introduction, 384\u003c\/p\u003e \u003cp\u003e21.2 BC Dressings, 385\u003c\/p\u003e \u003cp\u003e21.3 Bacterial Cellulose for Tissue Engineering and Regenerative Medicine, 388\u003c\/p\u003e \u003cp\u003e21.4 Concluding Remarks, 393\u003c\/p\u003e \u003cp\u003eAcknowledgments, 394\u003c\/p\u003e \u003cp\u003eReferences, 394\u003c\/p\u003e \u003cp\u003ePART IV\u003c\/p\u003e \u003cp\u003e\u003cb\u003e22 Molecularly Imprinted Cryogels for Protein Purification 403\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eMüge Andac¸, Igor Yu Galaev, and Adil Denizli\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e22.1 Introduction, 403\u003c\/p\u003e \u003cp\u003e22.2 Molecularly Imprinted Cryogels for Protein Purification, 405\u003c\/p\u003e \u003cp\u003e22.3 Some Selected Applications of Molecularly Imprinted Cryogels (MIC) for Macromolecules, 414\u003c\/p\u003e \u003cp\u003e22.4 Concluding Remarks and Future Perspectives, 421\u003c\/p\u003e \u003cp\u003eReferences, 423\u003c\/p\u003e \u003cp\u003e\u003cb\u003e23 Immunogenic Reaction of Implanted Biomaterials from Nature 429\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eMartijn Van Griensven and Elizabeth Rosado Balmayor\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e23.1 Introduction, 429\u003c\/p\u003e \u003cp\u003e23.2 Implantation Leads to Tissue Injury, 430\u003c\/p\u003e \u003cp\u003e23.3 Inflammatory Responses, 431\u003c\/p\u003e \u003cp\u003e23.4 Foreign Body Reaction, 433\u003c\/p\u003e \u003cp\u003e23.5 Immunogenic Reactions Towards Natural Biomaterials, 435\u003c\/p\u003e \u003cp\u003e23.6 Final Remarks, 438\u003c\/p\u003e \u003cp\u003eReferences, 438\u003c\/p\u003e \u003cp\u003e\u003cb\u003e24 Chemical Modification of Biomaterials from Nature 444\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eJ.C. Rodr´ýguez Cabello, I. Gonz´alez De Torre, M. Santos, A.M. Testera, and M. Alonso\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e24.1 Protein Modification, 444\u003c\/p\u003e \u003cp\u003e24.2 Lipid Modifications, 451\u003c\/p\u003e \u003cp\u003e24.3 Polysaccharide Chemical Modifications, 457\u003c\/p\u003e \u003cp\u003eReferences, 466\u003c\/p\u003e \u003cp\u003ePART V\u003c\/p\u003e \u003cp\u003e\u003cb\u003e25 Processing of Biomedical Devices for Tissue Engineering and Regenerative Medicine Applications 477\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eVitor M. Correlo, Albino Martins, Nuno M. Neves, and Rui L. Reis\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e25.1 Introduction, 477\u003c\/p\u003e \u003cp\u003e25.2 Processing Techniques of Naturally Derived Biomaterial, 478\u003c\/p\u003e \u003cp\u003e25.3 Processing Techniques of Natural-Based Polymeric Blends, 483\u003c\/p\u003e \u003cp\u003eReferences, 487\u003c\/p\u003e \u003cp\u003e\u003cb\u003e26 General Characterization of Physical Properties of Natural-Based Biomaterials 494\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eManuel Alatorre-Meda and Joäo F. Mano\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e26.1 Introduction, 494\u003c\/p\u003e \u003cp\u003e26.2 Bulk Properties, 495\u003c\/p\u003e \u003cp\u003e26.3 Surface Properties, 507\u003c\/p\u003e \u003cp\u003e26.4 Concluding Remarks, 512\u003c\/p\u003e \u003cp\u003eAcknowledgments, 512\u003c\/p\u003e \u003cp\u003eReferences, 512\u003c\/p\u003e \u003cp\u003e\u003cb\u003e27 General Characterization of Chemical Properties of Natural-Based Biomaterials 517\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eManuel Alatorre-Meda and Joäo F. Mano\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e27.1 Introduction, 517\u003c\/p\u003e \u003cp\u003e27.2 Molecular Weight and Elemental Composition, 518\u003c\/p\u003e \u003cp\u003e27.3 Physiological Degradation, 524\u003c\/p\u003e \u003cp\u003e27.4 Concluding Remarks, 527\u003c\/p\u003e \u003cp\u003eAcknowledgments, 529\u003c\/p\u003e \u003cp\u003eReferences, 529\u003c\/p\u003e \u003cp\u003e\u003cb\u003e28 In Vitro Biological Testing in the Development of New Devices 532\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eMarta L. Alves Da Silva, Albino Martins, Ana Costa-Pinto, Rui L. Reis, and Nuno M. Neves\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e28.1 Introduction, 532\u003c\/p\u003e \u003cp\u003e28.2 Cytotoxicity Assays, 533\u003c\/p\u003e \u003cp\u003e28.3 Evaluation of Cell Morphology and Distribution, 533\u003c\/p\u003e \u003cp\u003e28.4 Cell Viability Assays, 535\u003c\/p\u003e \u003cp\u003e28.5 Cell Proliferation Assays, 536\u003c\/p\u003e \u003cp\u003e28.6 Biochemical Analysis, 537\u003c\/p\u003e \u003cp\u003e28.7 Genotypic Expression Analysis, 541\u003c\/p\u003e \u003cp\u003e28.8 Histological Assessment, 542\u003c\/p\u003e \u003cp\u003e28.9 In Vitro Engineered Tissues, 543\u003c\/p\u003e \u003cp\u003e28.10 Concluding Remarks, 548\u003c\/p\u003e \u003cp\u003eReferences, 548\u003c\/p\u003e \u003cp\u003e\u003cb\u003e29 Advanced In-Vitro Cell Culture Methods Using Natural Biomaterials 551\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eMarta L. Alves Da Silva, Rui L. Reis, and Nuno M. Neves\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e29.1 Introduction, 551\u003c\/p\u003e \u003cp\u003e29.2 Bioreactors, 552\u003c\/p\u003e \u003cp\u003e29.3 Hypoxia, 553\u003c\/p\u003e \u003cp\u003e29.4 Co-Cultures, 555\u003c\/p\u003e \u003cp\u003e29.5 Transfection, 555\u003c\/p\u003e \u003cp\u003e29.6 Nanoparticles and Related Systems, 558\u003c\/p\u003e \u003cp\u003e29.7 Concluding Remarks, 559\u003c\/p\u003e \u003cp\u003eReferences, 559\u003c\/p\u003e \u003cp\u003e\u003cb\u003e30 Testing Natural Biomaterials in Animal Models 562\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eAna Costa-Pinto, Tírcia C. Santos, Nuno M. Neves, and Rui L. Reis\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e30.1 Laboratory Animals as Tools in Biomaterials Testing, 562\u003c\/p\u003e \u003cp\u003e30.2 Inflammation and Host Reaction, 564\u003c\/p\u003e \u003cp\u003e30.3 Animal Models for Tissue Engineering, 568\u003c\/p\u003e \u003cp\u003e30.4 Final Remarks, 574\u003c\/p\u003e \u003cp\u003eReferences, 575\u003c\/p\u003e \u003cp\u003ePART VI\u003c\/p\u003e \u003cp\u003e\u003cb\u003e31 Delivery Systems Made of Natural-Origin Polymers for Tissue Engineering and Regenerative Medicine Applications 583\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eAlbino Martins, Helena Ferreira, Rui L. Reis, and Nuno M. Neves\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e31.1 Introduction, 583\u003c\/p\u003e \u003cp\u003e31.2 Advantages and Disadvantages of Natural Polymers-Based Delivery Systems, 585\u003c\/p\u003e \u003cp\u003e31.3 Fundamentals of Drug Delivery, 586\u003c\/p\u003e \u003cp\u003e31.4 In Vitro and In Vivo Applications of Natural-Based Delivery Systems, 591\u003c\/p\u003e \u003cp\u003e31.5 Concluding Remarks, 601\u003c\/p\u003e \u003cp\u003eReferences, 602\u003c\/p\u003e \u003cp\u003e\u003cb\u003e32 Translational Research into New Clinical Applications 612\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eM. David Harmon and Sangamesh G. Kumbar\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e32.1 Introduction, 612\u003c\/p\u003e \u003cp\u003e32.2 Cardiovascular System Applications, 613\u003c\/p\u003e \u003cp\u003e32.3 Integumentary System Applications, 616\u003c\/p\u003e \u003cp\u003e32.4 Musculoskeletal System Applications, 618\u003c\/p\u003e \u003cp\u003e32.5 Nervous System Applications, 619\u003c\/p\u003e \u003cp\u003e32.6 Respiratory System Applications, 621\u003c\/p\u003e \u003cp\u003e32.7 Gastrointestinal System Applications, 622\u003c\/p\u003e \u003cp\u003e32.8 From Idea to Product, 624\u003c\/p\u003e \u003cp\u003eAcknowledgements, 626\u003c\/p\u003e \u003cp\u003eReferences, 626\u003c\/p\u003e \u003cp\u003e\u003cb\u003e33 Challenges and Opportunities of Natural Biomaterials for Advanced Devices and Therapies 629\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eR.L. Reis and N.M. Neves\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e33.1 Introduction, 629\u003c\/p\u003e \u003cp\u003e33.2 Challenges of Natural Biomaterials, 630\u003c\/p\u003e \u003cp\u003e33.3 Opportunities of Natural Biomaterials, 631\u003c\/p\u003e \u003cp\u003e33.4 Final Remarks, 631\u003c\/p\u003e \u003cp\u003eReferences, 632\u003c\/p\u003e \u003cp\u003e\u003cb\u003e34 Adhesives Inspired by Marine Mussels 634\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eCourtney L. Jenkins, Heather J. Meredith, and Jonathan J. Wilker\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e34.1 Introduction, 634\u003c\/p\u003e \u003cp\u003e34.2 Requirements for a Bioadhesive, 635\u003c\/p\u003e \u003cp\u003e34.3 Marine Mussels, 636\u003c\/p\u003e \u003cp\u003e34.4 Bulk Adhesion Testing, 638\u003c\/p\u003e \u003cp\u003e34.5 Extracted Mussel Adhesive Proteins, 640\u003c\/p\u003e \u003cp\u003e34.6 Mimics of Mussel Adhesive, 641\u003c\/p\u003e \u003cp\u003e34.7 Conclusions, 645\u003c\/p\u003e \u003cp\u003eAcknowledgement, 645\u003c\/p\u003e \u003cp\u003eReferences, 645\u003c\/p\u003e \u003cp\u003e\u003cb\u003e35 Final Comments and Remarks 649\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eR.L. Reis and N.M. Neves\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eINDEX 651\u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Other branches of medicine [\u003ca title=\"See our other books on Other branches of medicine\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Other%20branches%20of%20medicine%20%5BMM%5D%22\"\u003eMM\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Wiley","offers":[{"title":"Brand New","offer_id":52417777434904,"sku":"9781118478059","price":138.47,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/files\/9781118478059.jpg?v=1784508613","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/biomaterials-from-nature-for-advanced-devices-and-therapies-hardback-9781118478059","provider":"Freshly Printed Books","version":"1.0","type":"link"}