{"product_id":"biology-of-archaea-2-molecular-biology-of-archaea-from-genome-maintenance-to-the-regulation-of-gene-expression-hardback-9781789451696","title":"Biology of Archaea 2; Molecular Biology of Archaea, From Genome Maintenance to the Regulation of Gene Expression (Hardback) 9781789451696","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eBiology of Archaea 2\u003c\/font\u003e\u003cbr\u003e\r\n\u003cfont size=\"5\"\u003eMolecular Biology of Archaea, From Genome Maintenance to the Regulation of Gene Expression\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eBéatrice Clouet-d'Orval (Edited by), Béatrice Clouet–d′Orval (Author), Bruno Franzetti (Edited by), Bruno Franzetti (Author), Philippe Oger (Edited by), Philippe Oger (Author)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9781789451696, Wiley\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 8 July 2025\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e256 pages\u003cbr\u003e23.5 x 15.6 x 1.7 cm, 0.47 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003e\u003cp\u003eArchaea constitute a new branch of life alongside bacteria and eukaryotes. These microorganisms are unique in their cellular and molecular aspects. They have evolutionary links with the first eukaryotic cells and are now being used to elucidate fundamental biological questions.\u003c\/p\u003e \u003cp\u003eChampions of extremophilicity, archaea are helping to lift the veil on the limits of life on Earth. \u003ci\u003eBiology of Archaea 2\u003c\/i\u003e presents the diverse molecular mechanisms involved in the fundamental processes of genome maintenance and regulation of gene expression in archaeal cells.\u003c\/p\u003e \u003cp\u003eThis book analyzes the complex machinery involved in chromosome replication, DNA repair, RNA synthesis (transcription) and protein synthesis (translation), and explores the different classes of RNAs and enzymes involved in RNA maturation and degradation. These regulate the stability of messenger and regulatory non-coding RNAs, and contribute to the formation of the mature forms of ribosomal RNAs and transfer RNAs. These molecular mechanisms are closely related to those of eukaryotes.\u003c\/p\u003e\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e\u003cp\u003ePreface xi\u003cbr\u003e\u003ci\u003eBéatrice CLOUET-D'ORVAL, Bruno FRANZETTI and Philippe OGER\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eChapter 1. Replication of Archaeal Chromosomes 1\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eGhislaine HENNEKE, Roxane LESTINI, Marc NADAL and Didier FLAMENT\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e1.1. Replication initiation 2\u003c\/p\u003e \u003cp\u003e1.2. The elongation phase of replication 8\u003c\/p\u003e \u003cp\u003e1.3. Okazaki fragment maturation 10\u003c\/p\u003e \u003cp\u003e1.4. Restarting replication forks 15\u003c\/p\u003e \u003cp\u003e1.5. Replication termination 18\u003c\/p\u003e \u003cp\u003e1.6. Chromosome segregation and decatenation 18\u003c\/p\u003e \u003cp\u003e1.7. References 19\u003c\/p\u003e \u003cp\u003e\u003cb\u003eChapter 2. Archaeal DNA Repair 25\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eCaroline L'HERMITTE-STEAD, Anaïs BAYARD, Alexey ALEKSANDROV, Roxane LESTINI and Hannu MYLLYKALLIO\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2.1. General introduction 25\u003c\/p\u003e \u003cp\u003e2.2. Several different types of DNA damages occur in archaea 28\u003c\/p\u003e \u003cp\u003e2.3. Different archaeal DNA repair pathways 31\u003c\/p\u003e \u003cp\u003e2.4. Coordination of the different pathways by the replication clamp 40\u003c\/p\u003e \u003cp\u003e2.5. Summary and conclusion 42\u003c\/p\u003e \u003cp\u003e2.6. References 43\u003c\/p\u003e \u003cp\u003e\u003cb\u003eChapter 3. Transcription in Archaea 45\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eThomas FOUQUEAU, Duy KHANH PHUNG and Ludovic SAUGUET\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3.1. RNA polymerase 47\u003c\/p\u003e \u003cp\u003e3.2. The three stages of transcription 51\u003c\/p\u003e \u003cp\u003e3.3. Transcription regulation 64\u003c\/p\u003e \u003cp\u003e3.4. References 66\u003c\/p\u003e \u003cp\u003e\u003cb\u003eChapter 4. RNA Classes and Their Maturation and Degradation Enzymes 77\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eManon BATISTA, Béatrice CLOUET-D'ORVAL and Marie BOUVIER\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4.1. Introduction 77\u003c\/p\u003e \u003cp\u003e4.2. RNA classes in archaea 79\u003c\/p\u003e \u003cp\u003e4.3. Ribonuclease families in archaea 84\u003c\/p\u003e \u003cp\u003e4.4. Ubiquitous RNA-binding proteins in archaea 95\u003c\/p\u003e \u003cp\u003e4.5. Conclusion 100\u003c\/p\u003e \u003cp\u003e4.6. References 100\u003c\/p\u003e \u003cp\u003e\u003cb\u003eChapter 5. Ribosome and Transfer RNA Biogenesis 115\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eTamara BASTA and Sébastien FERREIRA-CERCA\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5.1. Ribosome biogenesis 116\u003c\/p\u003e \u003cp\u003e5.2. Synthesis and maturation of tRNAs 133\u003c\/p\u003e \u003cp\u003e5.3. Methodical toolboxes 156\u003c\/p\u003e \u003cp\u003e5.4. References 158\u003c\/p\u003e \u003cp\u003e\u003cb\u003eChapter 6. The Diversity and Function of Noncoding RNAs in Archaea 167\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eHubert F. BECKER and Christine GASPIN\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6.1. Introduction 167\u003c\/p\u003e \u003cp\u003e6.2. Noncoding RNA diversity 168\u003c\/p\u003e \u003cp\u003e6.3. ncRNA identification 178\u003c\/p\u003e \u003cp\u003e6.4. Circularization of noncoding RNAs 182\u003c\/p\u003e \u003cp\u003e6.5. Conclusion 185\u003c\/p\u003e \u003cp\u003e6.6. References 186\u003c\/p\u003e \u003cp\u003e\u003cb\u003eChapter 7. Translation in Archaea 193\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eEmmanuelle SCHMITT and Yves MECHULAM\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7.1. Initiating the translation 195\u003c\/p\u003e \u003cp\u003e7.2. Elongation peptide synthesis 206\u003c\/p\u003e \u003cp\u003e7.3. Translation termination and ribosome recycling 214\u003c\/p\u003e \u003cp\u003e7.4. Conclusion 219\u003c\/p\u003e \u003cp\u003e7.5. References 220\u003c\/p\u003e \u003cp\u003eList of Authors 233\u003c\/p\u003e \u003cp\u003eIndex 237\u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Clinical \u0026amp; internal medicine [\u003ca title=\"See our other books on Clinical \u0026amp; internal medicine\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Clinical%20\u0026amp;%20internal%20medicine%20%5BMJ%5D%22\"\u003eMJ\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Wiley-ISTE","offers":[{"title":"Brand New","offer_id":52446824431896,"sku":"9781789451696","price":99.69,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/files\/9781789451696.jpg?v=1785114842","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/biology-of-archaea-2-molecular-biology-of-archaea-from-genome-maintenance-to-the-regulation-of-gene-expression-hardback-9781789451696","provider":"Freshly Printed Books","version":"1.0","type":"link"}