{"product_id":"biological-dna-sensor-the-impact-of-nucleic-acids-on-diseases-and-vaccinology-hardback-9780124047327","title":"Biological DNA Sensor; The Impact of Nucleic Acids on Diseases and Vaccinology (Hardback) 9780124047327","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eBiological DNA Sensor\u003c\/font\u003e\u003cbr\u003e\r\n\u003cfont size=\"5\"\u003eThe Impact of Nucleic Acids on Diseases and Vaccinology\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cem\u003e\u003cp\u003eThe realization of the immunogenic properties of double stranded DNA and its implications in disease and vaccinology\u003c\/p\u003e\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eKen Ishii (Edited by), Choon Kit Tang (Edited by)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780124047327\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 7 November 2013\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e368 pages\u003cbr\u003e22.9 x 15.1 x 2.5 cm, 0.63 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cem\u003e\u003cfont size=\"3\"\u003e\u003cp\u003e\"The overall themes are the discovery of double-stranded DNA immunogenicity and the definition of DNA sensing pathways, double-stranded DNA and its part in modulating human diseases, and the DNA sensing pathway and its impact on vaccinology.\" --\u003cb\u003eProtoView.com, April 2014\u003c\/b\u003e\u003c\/p\u003e\u003c\/font\u003e\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003e\u003cp\u003e\u003ci\u003eBiological DNA Sensor\u003c\/i\u003e defines the meaning of DNA sensing pathways and demonstrates the importance of the innate immune responses induced by double stranded DNA (dsDNA) through its influencing functions in disease pathology and immune activity of adjuvants for vaccines. \u003c\/p\u003e  \u003cp\u003eThough discussed in specific subsections of existing books, dsDNA and its immunogenic properties has never received the complete treatment given in this book. \u003ci\u003eBiological DNA Sensor\u003c\/i\u003e approaches the impact of dsDNA's immunogenicity on disease and vaccinology holistically. It paints a complete and concise picture on the topic so you can understand this area of study and make more informed choices for your respective research needs. Chapters are authored by researchers who are renowned for their research focus, ensuring that this book provides the most complete views on the topics. \u003c\/p\u003e\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e\u003cp\u003e1. Route to discovering the immunogenic properties of DNA from TLR9 to cytosolic DNA sensors Choon Kit Tang, Cevayir Coban, Shizuo Akira, Ken J Ishii 2. The PYHIN family of molecules and their functions sensing dsDNA  Sivapriya Kailasan Vanaja, Vijay A. K. Rathinam, Katherine A. Fitzgerald 3. The central role of STING-TBK1 in the DNA sensing pathway  Glen Barber     4. Regulation of intracellular dsDNA-induced innate immune responses by autophagy-related proteins  Running title: Autophagy and dsDNA-induced innate immunity Tatsuya Saitoh 5. Host DNA Induced Inflammation and Autoimmune Diseases Surya Pandey, Taro Kawai 6. Systemic lupus erythematosus and the DNA sensing pathway  Ann Marshak-Rothstein     7. Bacterial infections and the DNA sensing pathway Jan Naujoks, Bastian Opitz 8. Viral infections and the DNA sensing pathway: lessons from herpesviruses and beyond Søren R. Paludan, Andrew G. Bowie 9. Cancer Pathogenesis and DNA sensing Shen Y.J., Lam A.R., Ho S.S.W., Koo C.X., Le Bert N., Gasser S. 10. Atherosclerosis and Aging and DNA sensing   Moshe Arditi 11. DNA Vaccines: Does it Target the Double Stranded-DNA Sensing Pathway?  Cevayir Coban, Miyuki Tozuka, Nao Jounai, Kouji Kobiyama, Fumihiko Takeshita, Choon Kit Tang, Ken J. Ishii 12. Adjuvants targeting the DNA sensing pathways – Alum based adjuvants Christophe J. Desmet 13. Adjuvants Targeting the DNA Sensing Pathways– Cyclic-di-GMP and Other Cyclic-di-Nucleotides  Rebecca Schmidt, Laurel L. Lenz\u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Genetics [\u003ca title=\"See our other books on Genetics\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Genetics%20%5Bnon-medical%5D%20%5BPSAK%5D%22\"\u003enon-medical PSAK\u003c\/a\u003e], Immunology [\u003ca title=\"See our other books on Immunology\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Immunology%20%5BMJCM%5D%22\"\u003eMJCM\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Freshly Printed Books","offers":[{"title":"Default Title","offer_id":46649387745560,"sku":"9780124047327","price":91.19,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/products\/9780124047327.jpg?v=1694100699","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/biological-dna-sensor-the-impact-of-nucleic-acids-on-diseases-and-vaccinology-hardback-9780124047327","provider":"Freshly Printed Books","version":"1.0","type":"link"}