{"product_id":"bayesian-methods-and-ethics-in-a-clinical-trial-design-hardback-9780471846802","title":"Bayesian Methods and Ethics in a Clinical Trial Design (Hardback) 9780471846802","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eBayesian Methods and Ethics in a Clinical Trial Design\u003c\/font\u003e\u003cbr\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003c\/p\u003e\n\u003cp\u003e\u003cfont size=\"4\"\u003eJoseph B. Kadane (Edited by), JB Kadane (Author)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780471846802, Wiley\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 4 March 1996\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e344 pages\u003cbr\u003e24.5 x 16.2 x 2.4 cm, 0.615 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cem\u003e\u003cfont size=\"3\"\u003e\"...Every practitioner and associated statistician involved in a clinical trial should read this book...\" (Statistical Methods in Medical Research, No.11, 2002)\u003c\/font\u003e\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003eHow to conduct clinical trials in an ethical and scientificallyresponsible manner\u003cbr\u003e \u003cbr\u003e This book presents a methodology for clinical trials that producesimproved health outcomes for patients while obtaining sound andunambiguous scientific data. It centers around a real-world testcase--involving a treatment for hypertension after open heartsurgery--and explains how to use Bayesian methods to accommodateboth ethical and scientific imperatives.\u003cbr\u003e \u003cbr\u003e The book grew out of the direct involvement in the project by adiverse group of experts in medicine, statistics, philosophy, andthe law. Not only do they contribute essays on the scientific,technological, legal, and ethical aspects of clinical trials, butthey also critique and debate each other's opinions, creating aninteresting, personalized text.\u003cbr\u003e \u003cbr\u003e Bayesian Methods and Ethics in a Clinical Trial Design\u003cbr\u003e * Answers commonly raised questions about Bayesian methods\u003cbr\u003e * Describes the advantages and disadvantages of this methodcompared with other methods\u003cbr\u003e * Applies current ethical theory to a particular class of designfor clinical trials\u003cbr\u003e * Discusses issues of informed consent and how to serve a patient'sbest interest while still obtaining uncontaminated scientific data\u003cbr\u003e * Shows how to use Bayesian probabilistic methods to createcomputer models from elicited prior opinions of medical experts onthe best treatment for a type of patient\u003cbr\u003e * Contains several chapters on the process, results, andcomputational aspects of the test case in question\u003cbr\u003e * Explores American law and the legal ramifications of using humansubjects\u003cbr\u003e \u003cbr\u003e For statisticians and biostatisticians, and for anyone involvedwith medicine and public health, this book provides both apractical guide and a unique perspective on the connection betweentechnological developments, human factors, and some of the largerethical issues of our times.\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003ePartial table of contents:\u003cbr\u003e \u003cbr\u003e MAJOR ISSUES.\u003cbr\u003e \u003cbr\u003e Ethically Optimizing Clinical Trials (K. Schaffner).\u003cbr\u003e \u003cbr\u003e Admissibility of Treatment (N. Sedransk).\u003cbr\u003e \u003cbr\u003e TEST CASE: VERAPAMIL\/NITROPRUSSIDE.\u003cbr\u003e \u003cbr\u003e The Mechanics of Conducting a Clinical Trial (E. Heitmiller \u0026amp;T. Blanck).\u003cbr\u003e \u003cbr\u003e Issues of Statistical Design (N. Sedransk).\u003cbr\u003e \u003cbr\u003e Operational History and Procedural Feasibility (J. Kadane).\u003cbr\u003e \u003cbr\u003e Verapamil versus Nitroprusside: Results of the Clinical Trial I (J.Kadane \u0026amp; N. Sedransk).\u003cbr\u003e \u003cbr\u003e Verapamil versus Nitroprusside: Results of the Clinical Trial II(E. Heitmiller, et al.).\u003cbr\u003e \u003cbr\u003e OTHER ISSUES.\u003cbr\u003e \u003cbr\u003e Author's Response to Commentaries I and II (D. Kairys).\u003cbr\u003e \u003cbr\u003e EPILOGUE.\u003cbr\u003e \u003cbr\u003e Epilogue (J. Kadane).\u003cbr\u003e \u003cbr\u003e Indexes.\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Mathematics [\u003ca title=\"See our other books on Mathematics\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Mathematics%20%5BPB%5D%22\"\u003ePB\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Wiley-Interscience","offers":[{"title":"Brand New","offer_id":52298062299416,"sku":"9780471846802","price":147.79,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/files\/9780471846802.jpg?v=1781733780","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/bayesian-methods-and-ethics-in-a-clinical-trial-design-hardback-9780471846802","provider":"Freshly Printed Books","version":"1.0","type":"link"}