{"product_id":"barriers-and-channels-formed-by-tight-junction-proteins-ii-volume-1258-paperback-softback-9781573318921","title":"Barriers and Channels Formed by Tight Junction Proteins II, Volume 1258 (Paperback \/ softback) 9781573318921","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eBarriers and Channels Formed by Tight Junction Proteins II, Volume 1258\u003c\/font\u003e\u003cbr\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003c\/p\u003e\n\u003cp\u003e\u003cfont size=\"4\"\u003eMichael Fromm (Edited by), M Fromm (Author), Jörg-Dieter Schulzke (Edited by)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9781573318921, Wiley\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003ePaperback \/ softback, published 17 August 2012\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e191 pages\u003cbr\u003e25.5 x 17.8 x 0.9 cm, 0.435 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003e\u003cp\u003eTight junction proteins connect epithelial and endothelial cells and, importantly, form selective barriers and channels for paracellular transportation.  Two types of tight junction proteins—the claudin family (claudins-1 to -27) and the TAMP family (occludin, Marvel-D2, and tricellulin)—can be distinguished molecularly and functionally.  Recent work has focused on delineating the functional significance of differences in selective permeability, for example, by examining the regulatory mechanisms of tight junctions.  This work is of great clinical importance as many inflammatory or infectious diseases are characterized by increased permeability and the manipulation of tight junctions presents a new horizon in the development of novel therapeutics.  The volume \u003ci\u003eBarriers and Channels Formed by Tight Junction Proteins II\u003c\/i\u003e provides a detailed look at the recent advances in our understanding of tight junction regulation and dysregulation.  The papers included focus on three major themes: inflammation and gastrointestinal function; epithelial transport, barrier modulation, and food components; and tight junctions in intestinal and renal epithelia.\u003c\/p\u003e \u003cp\u003eNOTE: Annals volumes are available for sale as individual books or as a journal. For more information on instutional journal subscriptions, please visit \u003ca href=\"http:\/\/ordering.onlinelibrary.wiley.com\/subs.asp?ref=1749-6632\u0026amp;doi=10.111\/(ISSN)1749-6632\"\u003ehttp:\/\/ordering.onlinelibrary.wiley.com\/subs.asp?ref=1749-6632\u0026amp;doi=10.111\/(ISSN)1749-6632\u003c\/a\u003e\u003c\/p\u003e \u003cp\u003eACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (\u003ca href=\"http:\/\/www.nyas.org\"\u003ewww.nyas.org\u003c\/a\u003e). Members of the New York Academy of Science receive full-text access to \u003ci\u003eAnnals\u003c\/i\u003e online and discounts on print volumes. Please visit \u003ca href=\"http:\/\/www.nyas.org\/MemberCenter\/Join.aspx\"\u003ehttp:\/\/www.nyas.org\/MemberCenter\/Join.aspx\u003c\/a\u003e for more information on becoming a member.\u003c\/p\u003e\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eTNF-[alpha]-induced intestinal epithelial cell shedding : implications for intestinal barrier function \/ Alastair J.M. Watson and Kevin R. Hughes \u003cp\u003eTight junctions on the move : molecular mechanisms for epithelial barrier regulation \/ Le Shen\u003c\/p\u003e \u003cp\u003eHIV infection and the intestinal mucosal barrier \/ Hans-Jörg Epple and Martin Zeitz\u003c\/p\u003e \u003cp\u003eZonulin, regulation of tight junctions, and autoimmune diseases \/ Alessio Fasano\u003c\/p\u003e \u003cp\u003eMyosin light chain kinase : pulling the strings of epithelial tight junction function \/ Kevin E. Cunningham and Jerrold R. Turner\u003c\/p\u003e \u003cp\u003eDefective tight junctions in refractory celiac disease \/ Michael Schumann [and others]\u003c\/p\u003e \u003cp\u003eMicrobial butyrate and its role for barrier function in the gastrointestinal tract \/ Svenja Plöger [and others]\u003c\/p\u003e \u003cp\u003eSUMOylation of claudin-2 \/ Christina M. Van Itallie, Laura L. Mitic and James M. Anderson\u003c\/p\u003e \u003cp\u003eProof of concept for claudin-targeted drug development \/ Hidehiko Suzuki [and others]\u003c\/p\u003e \u003cp\u003eLoss of enteral nutrition in a mouse model results in intestinal epithelial barrier dysfunction \/ Yongjia Feng [and others]\u003c\/p\u003e \u003cp\u003eThe protein C pathway in intestinal barrier function : challenging the hemostasis paradigm \/ Silvia D'Alessio, Marco Genua and Stefania Vetrano\u003c\/p\u003e \u003cp\u003eAnalysis of absorption enhancers in epithelial cell models \/ Rita Rosenthal [and others]\u003c\/p\u003e \u003cp\u003eCalcium regulation of tight junction permeability \/ Markus Bleich, Qixian Shan and Nina Himmerkus\u003c\/p\u003e \u003cp\u003eEffects of quercetin studied in colonic HT-29\/B6 cells and rat intestine in vitro \/ Maren Amasheh [and others]\u003c\/p\u003e \u003cp\u003eClaudin-based paracellular proton barrier in the stomach \/ Atsushi Tamura [and others]\u003c\/p\u003e \u003cp\u003eRegulation of epithelial proliferation by tight junction proteins \/ Attila E. Farkas, Christopher T. Capaldo and Asma Nusrat\u003c\/p\u003e \u003cp\u003eBarrier dysfunction and bacterial uptake in the follicle-associated epithelium of ileal Crohn's disease \/ Åsa V. Keita and Johan D. Söderholm\u003c\/p\u003e \u003cp\u003eThe protozoan pathogen Toxoplasma gondii targets the paracellular pathway to invade the intestinal epithelium \/ Caroline M. Weight and Simon R. Carding\u003c\/p\u003e \u003cp\u003eIon transport and barrier function are disturbed in microscopic colitis \/ Christian Barmeyer [and others]\u003c\/p\u003e \u003cp\u003eEnteropathogenic E. coli effectors EspG1\/G2 disrupt tight junctions : new roles and mechanisms \/ Lila G. Glotfelty and Gail A. Hecht\u003c\/p\u003e \u003cp\u003eAbnormal intestinal permeability in Crohn's disease pathogenesis \/ Christopher W. Teshima, Levinus A. Dieleman and Jon B. Meddings\u003c\/p\u003e \u003cp\u003eA dynamic paracellular pathway serves diuresis in mosquito Malpighian tubules \/ Klaus W. Beyenbach\u003c\/p\u003e \u003cp\u003eImpaired paracellular ion transport in the loop of Henle causes familial hypomagnesemia with hypercalciuria and nephrocalcinosis \/ Lea Haisch and Martin Konrad\u003c\/p\u003e \u003cp\u003eThe yin and yang of claudin-14 function in human diseases \/ Jianghui Hou\u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Biology, life sciences [\u003ca title=\"See our other books on Biology, life sciences\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Biology,%20life%20sciences%20%5BPS%5D%22\"\u003ePS\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Wiley-Blackwell","offers":[{"title":"Brand New","offer_id":52441901072664,"sku":"9781573318921","price":56.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/files\/9781573318921.jpg?v=1785028035","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/barriers-and-channels-formed-by-tight-junction-proteins-ii-volume-1258-paperback-softback-9781573318921","provider":"Freshly Printed Books","version":"1.0","type":"link"}