{"product_id":"applied-mixed-models-in-medicine-hardback-9780470023563","title":"Applied Mixed Models in Medicine (Hardback) 9780470023563","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eApplied Mixed Models in Medicine\u003c\/font\u003e\u003cbr\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003c\/p\u003e\n\u003cp\u003e\u003cfont size=\"4\"\u003eHelen Brown (Author), Robin Prescott (Author)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780470023563, Wiley\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 7 April 2006\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e480 pages\u003cbr\u003e23.4 x 16.2 x 3.1 cm, 0.879 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cem\u003e\u003cfont size=\"3\"\u003e\"…a valuable mixed model resource for most applied statisticians working in the medical environment.\" (\u003ci\u003eBiometrics\u003c\/i\u003e, June 2007)  \u003cp\u003e\"…useful for practitioners and applied statisticians working in medical science.\" (\u003ci\u003eJournal of the American Statistical Association\u003c\/i\u003e, September 2007)\u003c\/p\u003e \u003cp\u003e\"…takes a practical rather than theoretical approach and requires understanding of only basic statistics.\" (\u003ci\u003eMAA Reviews\u003c\/i\u003e, October 30, 2006)\u003c\/p\u003e \u003cp\u003e“This second edition gives an overview of the theory of mixed models and its application to real data in medical research.” (\u003ci\u003eZentralblatt MATH,\u003c\/i\u003e April 2007)\u003c\/p\u003e\u003c\/font\u003e\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003eA mixed model allows the incorporation of both fixed and random variables within a statistical analysis. This enables efficient inferences and more information to be gained from the data. The application of mixed models is an increasingly popular way of analysing medical data, particularly in the pharmaceutical industry. There have been many recent advances in mixed modelling, particularly regarding the software and applications. This new edition of a groundbreaking text discusses the latest developments, from updated SAS techniques to the increasingly wide range of applications.  \u003cul\u003e \u003cli\u003ePresents an overview of the theory and applications of mixed models in medical research, including the latest developments and new sections on bioequivalence, cluster randomised trials and missing data.\u003c\/li\u003e \u003cli\u003eEasily accessible to practitioners in any area where mixed models are used, including medical statisticians and economists.\u003c\/li\u003e \u003cli\u003eIncludes numerous examples using real data from medical and health research, and epidemiology, illustrated with SAS code and output.\u003c\/li\u003e \u003cli\u003eFeatures new version of SAS, including the procedure PROC GLIMMIX and an introduction to other available software.\u003c\/li\u003e \u003cli\u003eSupported by a website featuring computer code, data sets, and further material, available at: http:\/\/www.chs.med.ed.ac.uk\/phs\/mixed\/.\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eThis much-anticipated second edition is ideal for applied statisticians working in medical research and the pharmaceutical industry, as well as teachers and students of statistics courses in mixed models. The text will also be of great value to a broad range of scientists, particularly those working the medical and pharmaceutical areas.\u003c\/p\u003e\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e\u003cb\u003ePreface to Second Edition.\u003c\/b\u003e  \u003cp\u003e\u003cb\u003eMixed Model Notations.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 Introduction.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1.1 The Use of Mixed Models.\u003c\/p\u003e \u003cp\u003e1.2 Introductory Example.\u003c\/p\u003e \u003cp\u003e1.3 A Multi-Centre Hypertension Trial.\u003c\/p\u003e \u003cp\u003e1.4 Repeated Measures Data.\u003c\/p\u003e \u003cp\u003e1.5 More aboutMixed Models.\u003c\/p\u003e \u003cp\u003e1.6 Some Useful Definitions.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 NormalMixed Models.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e2.1 Model Definition.\u003c\/p\u003e \u003cp\u003e2.2 Model Fitting Methods.\u003c\/p\u003e \u003cp\u003e2.3 The Bayesian Approach.\u003c\/p\u003e \u003cp\u003e2.4 Practical Application and Interpretation.\u003c\/p\u003e \u003cp\u003e2.5 Example.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Generalised Linear MixedModels.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e3.1 Generalised Linear Models.\u003c\/p\u003e \u003cp\u003e3.2 Generalised Linear Mixed Models.\u003c\/p\u003e \u003cp\u003e3.3 Practical Application and Interpretation.\u003c\/p\u003e \u003cp\u003e3.4 Example.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Mixed Models for Categorical Data.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e4.1 Ordinal Logistic Regression (Fixed Effects Model).\u003c\/p\u003e \u003cp\u003e4.2 Mixed Ordinal Logistic Regression.\u003c\/p\u003e \u003cp\u003e4.3 Mixed Models for Unordered Categorical Data.\u003c\/p\u003e \u003cp\u003e4.4 Practical Application and Interpretation.\u003c\/p\u003e \u003cp\u003e4.5 Example.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Multi-Centre Trials and Meta-Analyses.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e5.1 Introduction to Multi-Centre Trials.\u003c\/p\u003e \u003cp\u003e5.2 The Implications of using Different Analysis Models.\u003c\/p\u003e \u003cp\u003e5.3 Example: A Multi-Centre Trial.\u003c\/p\u003e \u003cp\u003e5.4 Practical Application and Interpretation.\u003c\/p\u003e \u003cp\u003e5.5 Sample Size Estimation.\u003c\/p\u003e \u003cp\u003e5.6 Meta-Analysis.\u003c\/p\u003e \u003cp\u003e5.7 Example: Meta-analysis.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 RepeatedMeasures Data.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e6.1 Introduction.\u003c\/p\u003e \u003cp\u003e6.2 Covariance Pattern Models.\u003c\/p\u003e \u003cp\u003e6.3 Example: Covariance Pattern Models for Normal Data.\u003c\/p\u003e \u003cp\u003e6.4 Example: Covariance Pattern Models for Count Data.\u003c\/p\u003e \u003cp\u003e6.5 Random Coefficients Models.\u003c\/p\u003e \u003cp\u003e6.6 Examples of Random Coefficients Models.\u003c\/p\u003e \u003cp\u003e6.7 Sample Size Estimation.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 Cross-Over Trials.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e7.1 Introduction.\u003c\/p\u003e \u003cp\u003e7.2 Advantages of Mixed Models in Cross-Over Trials.\u003c\/p\u003e \u003cp\u003e7.3 The AB\/BA Cross-Over Trial.\u003c\/p\u003e \u003cp\u003e7.4 Higher Order Complete Block Designs.\u003c\/p\u003e \u003cp\u003e7.5 Incomplete Block Designs.\u003c\/p\u003e \u003cp\u003e7.6 Optimal Designs.\u003c\/p\u003e \u003cp\u003e7.7 Covariance Pattern Models.\u003c\/p\u003e \u003cp\u003e7.8 Analysis of Binary Data.\u003c\/p\u003e \u003cp\u003e7.9 Analysis of Categorical Data.\u003c\/p\u003e \u003cp\u003e7.10 Use of Results from Random Effects Models in Trial Design.\u003c\/p\u003e \u003cp\u003e7.11 General Points.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 Other Applications of MixedModels.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e8.1 Trials with Repeated Measurements within Visits.\u003c\/p\u003e \u003cp\u003e8.2 Multi-Centre Trials with Repeated Measurements.\u003c\/p\u003e \u003cp\u003e8.3 Multi-Centre Cross-Over Trials.\u003c\/p\u003e \u003cp\u003e8.4 Hierarchical Multi-Centre Trials and Meta-Analysis.\u003c\/p\u003e \u003cp\u003e8.5 Matched Case–Control Studies.\u003c\/p\u003e \u003cp\u003e8.6 Different Variances for Treatment Groups in a Simple Between-Patient Trial.\u003c\/p\u003e \u003cp\u003e8.7 Estimating Variance Components in an Animal Physiology Trial.\u003c\/p\u003e \u003cp\u003e8.8 Inter- and Intra-Observer Variation in Foetal Scan Measurements.\u003c\/p\u003e \u003cp\u003e8.9 Components of Variation and Mean Estimates in a Cardiology Experiment.\u003c\/p\u003e \u003cp\u003e8.10 Cluster Sample Surveys.\u003c\/p\u003e \u003cp\u003e8.11 Small AreaMortality Estimates.\u003c\/p\u003e \u003cp\u003e8.12 Estimating Surgeon Performance.\u003c\/p\u003e \u003cp\u003e8.13 Event History Analysis.\u003c\/p\u003e \u003cp\u003e8.14 A Laboratory Study Using aWithin-Subject 4 × 4 Factorial Design.\u003c\/p\u003e \u003cp\u003e8.15 Bioequivalence Studies with Replicate Cross-Over Designs.\u003c\/p\u003e \u003cp\u003e8.16 Cluster Randomised Trials.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 Software for Fitting MixedModels.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e9.1 Packages for Fitting Mixed Models.\u003c\/p\u003e \u003cp\u003e9.2 Basic use of PROC MIXED.\u003c\/p\u003e \u003cp\u003e9.3 Using SAS to Fit Mixed Models to Non-Normal Data.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eGlossary.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eReferences.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eIndex.\u003c\/b\u003e\u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Mathematics [\u003ca title=\"See our other books on Mathematics\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Mathematics%20%5BPB%5D%22\"\u003ePB\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Wiley","offers":[{"title":"Brand New","offer_id":52256240468248,"sku":"9780470023563","price":86.19,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/files\/9780470023563.jpg?v=1781274506","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/applied-mixed-models-in-medicine-hardback-9780470023563","provider":"Freshly Printed Books","version":"1.0","type":"link"}