{"product_id":"annual-reports-in-medicinal-chemistry-paperback-9780128001677","title":"Annual Reports in Medicinal Chemistry (Paperback) 9780128001677","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eAnnual Reports in Medicinal Chemistry\u003c\/font\u003e\u003cbr\u003e\r\n\r\n\r\n\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eA compendium of information on newly approved drugs and compounds entering late-stage clinical trials, and a valuable resource for graduate students pursuing research in medicinal chemistry\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eManoj C Desai (Series edited by)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780128001677\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003ePaperback, published 29 September 2014\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e636 pages\u003cbr\u003e22.9 x 15.1 x 3.9 cm, 0.96 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003e\u003ci\u003eAnnual Reports in Medicinal Chemistry\u003c\/i\u003e provides timely and critical reviews of important topics in medicinal chemistry with an emphasis on emerging topics in the biological sciences that are expected to provide the basis for entirely new future therapies.\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e\u003col\u003e\u003cb\u003e \u003cli\u003eA Personal Essay: My Experiences in the Pharmaceutical Industry\u003c\/li\u003e \u003cli\u003eAdventures in Medicinal Chemistry - A Career in Drug Discovery\u003c\/li\u003e \u003cli\u003eNatural and Synthetic Neuroactive Steroid (NAS) Modulators of GABA\u003csub\u003eA\u003c\/sub\u003e and NMDA Receptors\u003c\/li\u003e \u003cli\u003eDevelopment of LRRK2 Kinase Inhibitors for Parkinson’s Disease\u003c\/li\u003e \u003cli\u003eStimulating Neurotrophin Receptors in the Treatment of Neurodegenerative Disorders\u003c\/li\u003e \u003cli\u003eSmall Molecule Modulators of GPR40 (FFA1)\u003c\/li\u003e \u003cli\u003eRecent Advances in the Development of P2Y\u003csub\u003e12\u003c\/sub\u003e Receptor Antagonists as Antiplatelet Agents\u003c\/li\u003e \u003cli\u003eCurrent Approaches to the Treatment of Atrial Fibrillation\u003c\/li\u003e \u003cli\u003eAdvances in the Discovery of Small Molecule IRAK4 Inhibitors\u003c\/li\u003e \u003cli\u003eH\u003csub\u003e4\u003c\/sub\u003e Receptor Antagonists and Their Potential Therapeutic Applications\u003c\/li\u003e \u003cli\u003eUrate Crystal Deposition Disease and Gout - New Therapies for an Old Problem\u003c\/li\u003e \u003cli\u003ep53 - MDM2 and MDMX Antagonists\u003c\/li\u003e \u003cli\u003eModulators of Atypical Protein Kinase C as Anticancer Agents\u003c\/li\u003e \u003cli\u003eAdvancement of Cell Wall Inhibitors in \u003ci\u003eMycobacterium Tuberculosis\u003c\/i\u003e\n\u003c\/li\u003e \u003cli\u003eNucleosides and Nucleotides for the Treatment of Viral Diseases\u003c\/li\u003e \u003cli\u003eAdvances in Inhibitors of Penicillin Binding Proteins and ß-lactamases as Antibacterial Agents\u003c\/li\u003e \u003cli\u003eTumor Microenvironment as Target in Cancer Therapy\u003c\/li\u003e \u003cli\u003eNovel Screening Paradigms for the Identification of Allosteric Modulators and \/or Biased Ligands for Challenging G-Protein-Coupled Receptors (GPCRs)\u003c\/li\u003e \u003cli\u003eMer Tyrosine Kinase Receptor: Therapeutic Opportunities in Oncology, Virology and Cardiovascular Indications\u003c\/li\u003e \u003cli\u003eDisease Modifying Agents for the Treatment of Cystic Fibrosis\u003c\/li\u003e \u003cli\u003eAdvancements in Stapled Peptide Drug Discovery and Development\u003c\/li\u003e \u003cli\u003eCytochrome P450 Enzyme Metabolites in Lead Discovery and Development\u003c\/li\u003e \u003cli\u003eCase History: Forxiga\u003csup\u003eTM\u003c\/sup\u003e (Dapagliflozin), a Potent Selective SGLT2 Inhibitor for Treatment of Diabetes\u003c\/li\u003e \u003cli\u003eCase History: Kalydeco® (VX-770, Ivacaftor), a CFTR Potentiator for the Treatment of Patients with Cystic Fibrosis and the \u003ci\u003eG551D-CFTR\u003c\/i\u003e Mutation\u003c\/li\u003e \u003cli\u003eCase History: Xeljanz\u003csup\u003eTM\u003c\/sup\u003e (Tofacitinib Citrate), A First-In-Class Janus Kinase (JAK) Inhibitor for the Treatment of Rheumatoid Arthritis\u003c\/li\u003e \u003cli\u003eNew Chemical Entities Entering Phase III Trials in 2013\u003c\/li\u003e \u003cli\u003eTo Market, To Market – 2013\u003c\/li\u003e\u003c\/b\u003e\u003c\/ol\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Organic chemistry [\u003ca title=\"See our other books on Organic chemistry\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Organic%20chemistry%20%5BPNN%5D%22\"\u003ePNN\u003c\/a\u003e], Pharmacology [\u003ca title=\"See our other books on Pharmacology\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Pharmacology%20%5BMMG%5D%22\"\u003eMMG\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Freshly Printed Books","offers":[{"title":"Default Title","offer_id":46649441288472,"sku":"9780128001677","price":80.49,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/products\/9780128001677.jpg?v=1694100985","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/annual-reports-in-medicinal-chemistry-paperback-9780128001677","provider":"Freshly Printed Books","version":"1.0","type":"link"}