{"product_id":"animal-and-translational-models-for-cns-drug-discovery-psychiatric-disorders-hardback-9780123738561","title":"Animal and Translational Models for CNS Drug Discovery: Psychiatric Disorders (Hardback) 9780123738561","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eAnimal and Translational Models for CNS Drug Discovery: Psychiatric Disorders\u003c\/font\u003e\u003cbr\u003e\r\n\r\n\r\n\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eYour guide for understanding the selection and use of animal translational models for psychiatric drugs\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eRobert A. McArthur (Edited by), Franco Borsini (Edited by)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780123738561, Elsevier Science\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 17 November 2008\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e528 pages\u003cbr\u003e26 x 18.3 x 3.1 cm, 1.14 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003e\u003cp\u003e\u003ci\u003ePsychiatric Disorders\u003c\/i\u003e is written for researchers in both academia and the pharmaceutical industry who use animal models in research and development of drugs for psychiatric disorders such as anxiety, obsessive-compulsive disorder, depression, schizophrenia, bipolar disorder, ADHD, and autistic spectrum disorder. \u003ci\u003ePsychiatric Disorders \u003c\/i\u003ehas introductory chapters expressing the view of the role and relevance of animal models for drug discovery and development for the treatment of psychiatric disorders from the perspective of (a) academic basic neuroscientific research, (b) applied pharmaceutical drug discovery and development, and (c) issues of clinical trial design and regulatory agencies limitations. Each volume examines the rationale, use, robustness and limitations of animal models in each therapeutic area covered and discuss the use of animal models for target identification and validation. The clinical relevance of animal models is discussed in terms of major limitations in cross-species comparisons, clinical trial design of drug candidates, and how clinical trial endpoints could be improved. The aim of this series of volumes on \u003ci\u003eAnimal and Translational Models for CNS Drug Discovery\u003c\/i\u003e is to identify and provide common endpoints between species that can serve to inform both the clinic and the bench with the information needed to accelerate clinically-effective CNS drug discovery.\u003c\/p\u003e  \u003cp\u003eThis is the first volume in the three volume-set, \u003ci\u003eAnimal and Translational Models for CNS Drug Discovery\u003c\/i\u003e 978-0-12-373861-5, and is also available for purchase individually. \u003c\/p\u003e\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003ePreface to Psychiatric Disorders Volume:\u003cbr\u003eWhat Do You Mean By “Translational Research?? An Enquiry through Animal and Translational Models for CNS Drug Discovery: Psychiatric Disorders\u003cbr\u003eRobert A McArthur and Franco Borsini\u003cbr\u003e\u003cbr\u003e1.\tMark J. Millan. The Discovery and Development of Pharmacotherapy for Psychiatric Disorders: A Critical Survey of Animal and Translational Models, and Perspectives for their Improvement\u003cbr\u003e\u003cbr\u003e2.\tL. Winsky et al. Drug Discovery and Development Initiatives at the National Institute of Mental Health:  From Cell-Based System to Proof of Concept\u003cbr\u003e\u003cbr\u003e3.\tJ. McEvoy and Freudenreich. Issues in the Design and Conductance of Clinical Trials\u003cbr\u003e\u003cbr\u003e4.\tKlaus A. Miczek. Challenges for Translational Psychopharmacology Research – The Need for Conceptual Principles\u003cbr\u003e\u003cbr\u003e5.\tT. Steckler et al. Developing Novel Anxiolytics:  Improving Preclinical Detection and Clinical Assessment\u003cbr\u003e\u003cbr\u003e6.\tD. Joel et al. Animal Models of Obsessive-Compulsive Disorder:  From Bench to Beside Via Endophenotypes and Biomarkers\u003cbr\u003e\u003cbr\u003e7.\tJ. Cryan et al. Developing More Efficacious Antidepressant Medications:\u003cbr\u003eImproving and Aligning Preclinical and Clinical Assessment Tools\u003cbr\u003e\u003cbr\u003e8.\tD. Jones et al. Developing New Drugs for Schizophrenia: From Animals to the Clinic\u003cbr\u003e\u003cbr\u003e9.\tC. Large et al. Developing Therapeutics for Bipolar Disorder (BPD):  From Animal Models to the Clinic\u003cbr\u003e\u003cbr\u003e10.\tR. Tannock et al. Towards a Biological Understanding of ADHD and the Discovery of Novel Therapeutic Approaches\u003cbr\u003e\u003cbr\u003e11.\tJ. Bartz et al. Preclinical Animal Models of Autistic Spectrum Disorders (ASD)\u003cbr\u003e\u003cbr\u003e12.\t S. Doran et al. Translational Models of Sleep and Sleep Disorders\t\u003cbr\u003e\u003cbr\u003eEpilogue:\u003cbr\u003eTranslational Models for the 21st century: Reminiscence, Reflections and Some Recommendations\u003cbr\u003ePaul Willner, Franco Borsini, and Robert A McArthur\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Pharmaceutical technology [\u003ca title=\"See our other books on Pharmaceutical technology\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Pharmaceutical%20technology%20%5BTDCW%5D%22\"\u003eTDCW\u003c\/a\u003e], Psychiatry [\u003ca title=\"See our other books on Psychiatry\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Psychiatry%20%5BMMH%5D%22\"\u003eMMH\u003c\/a\u003e], Psychopharmacology [\u003ca title=\"See our other books on Psychopharmacology\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Psychopharmacology%20%5BMMGW%5D%22\"\u003eMMGW\u003c\/a\u003e], Pharmacology [\u003ca title=\"See our other books on Pharmacology\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Pharmacology%20%5BMMG%5D%22\"\u003eMMG\u003c\/a\u003e], Pharmaceutical industries [\u003ca title=\"See our other books on Pharmaceutical industries\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Pharmaceutical%20industries%20%5BKNDP%5D%22\"\u003eKNDP\u003c\/a\u003e], Psychology [\u003ca title=\"See our other books on Psychology\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Psychology%20%5BJM%5D%22\"\u003eJM\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Academic Press","offers":[{"title":"Default Title","offer_id":46649278431512,"sku":"9780123738561","price":63.29,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/products\/9780123738561.jpg?v=1695013826","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/animal-and-translational-models-for-cns-drug-discovery-psychiatric-disorders-hardback-9780123738561","provider":"Freshly Printed Books","version":"1.0","type":"link"}