{"product_id":"analysis-and-purification-methods-in-combinatorial-chemistry-hardback-9780471269298","title":"Analysis and Purification Methods in Combinatorial Chemistry (Hardback) 9780471269298","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eAnalysis and Purification Methods in Combinatorial Chemistry\u003c\/font\u003e\u003cbr\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003c\/p\u003e\n\u003cp\u003e\u003cfont size=\"4\"\u003eBing Yan (Edited by), B Yan (Author)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780471269298, Wiley\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 9 January 2004\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e496 pages, Charts: 61 B\u0026amp;W, 0 Color; Photos: 13 B\u0026amp;W, 0 Color; Drawings: 20 B\u0026amp;W, 0 Color; Screen captures: 15 B\u0026amp;W, 0 Color; Tables: 38 B\u0026amp;W, 0 Color; Graphs: 107 B\u0026amp;W, 0 Color\u003cbr\u003e23.8 x 15.8 x 2.7 cm, 0.751 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cem\u003e\u003cfont size=\"3\"\u003e\"…a timely and valuable volume that would be an excellent addition to university libraries and the collections of individuals…\" (\u003ci\u003eE-STREAMS\u003c\/i\u003e, February 2005)  \u003cp\u003e\"...a useful book for chemists entering the field from either analytical or synthetic organic chemistry backgrounds.” (\u003ci\u003eAngewandte Chemie International Edition\u003c\/i\u003e, September 6, 2004)\u003c\/p\u003e \u003cp\u003e\"This useful volume is a worthwhile addition to institute libraries as well as to the libraries students and researchers who are working in analytical chemistry, medicinal chemistry, organic chemistry, biotechnology…\" (\u003ci\u003eEnergy Sources\u003c\/i\u003e, August 2004)\u003c\/p\u003e\u003c\/font\u003e\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003eQuality measurement, control, and improvement in combinatorial chemistry\u003cbr\u003e Combinatorial chemistry has developed rapidly in the past decade, with great advances made by scientists working on analysis and purification of a large number of compounds and the analysis of polymer-bound compounds. However, formidable challenges lie ahead of today's researcher. For example, high-throughput analysis and purification technologies must be further developed to ensure combinatorial libraries are \"purifiable,\" and \"drugable.\"\u003cbr\u003e To this end, Analysis and Purification Methods in Combinatorial Chemistry describes various analytical techniques and systems for the development, validation, quality control, purification, and physicochemical testing of combinatorial libraries. A new volume in Wiley's Chemical Analysis series, this text has four parts covering:\u003cbr\u003e * Various approaches to monitoring reactions on solid support and optimizing reactions for library synthesis\u003cbr\u003e * High-throughput analytical methods used to analyze the quality of libraries\u003cbr\u003e * High-throughput purification techniques\u003cbr\u003e * Analytical methods applied in post-synthesis and post-purification stages\u003cbr\u003e Drawing from the contributions of respected experts in combinatorial chemistry, this comprehensive book provides coverage of applications of Nuclear Magnetic Resonance (NMR), liquid chromatography\/mass spectrometry (LC\/MS), Fourier Transform Infrared (FTIR), micellar electrokinetic chromatography (MEKC) technologies, as well as other analytical techniques.\u003cbr\u003e This eminently useful volume is an essential addition to the library of students and researchers studying or working in analytical chemistry, combinatorial chemistry, medicinal chemistry, organic chemistry, biotechnology, biochemistry, or biophysics.\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003ePreface.  \u003cp\u003eContributors.\u003c\/p\u003e \u003cp\u003ePART I: ANALYSIS FOR FEASIBILITY AND OPTIMIZATION OF LIBRARY SYNTHESIS.\u003c\/p\u003e \u003cp\u003eChapter 1. Quantitative Analysis in Organic Synthesis with NMR (L. Lucas \u0026amp; C. Larive).\u003c\/p\u003e \u003cp\u003eChapter 2. \u003csup\u003e19\u003c\/sup\u003eF Gel-phase NMR Spectroscopy for Reaction Monitoring and Quantification of Resin Loading (J. Salvino).\u003c\/p\u003e \u003cp\u003eChapter 3. The Application of Single-Bead FTIR and Color Test for Reaction Monitoring and Building Block Validation in Combinatorial Library Sysnthesis(J. Cournoyer, \u003ci\u003eet al\u003c\/i\u003e.).\u003c\/p\u003e \u003cp\u003eChapter 4. HR-MAS NMR Analysis of Compounds Attached to Polymer Supports (M. Guinó \u0026amp; Y. de Miguel).\u003c\/p\u003e \u003cp\u003eChapter 5. Multivariate Tools for Real-Time Monitoring and Optimization of Combinatorial Materials and Process Conditions (R. Potyrailo, \u003ci\u003eet al\u003c\/i\u003e.).\u003c\/p\u003e \u003cp\u003eChapter 6. Mass Spectrometry and Soluble Polymeric Supports (C. Enjalbal, \u003ci\u003eet al\u003c\/i\u003e.).\u003c\/p\u003e \u003cp\u003ePART II: HIGH-THROUGHPUT ANALYSIS FOR LIBRARY QUALITY CONTROL.\u003c\/p\u003e \u003cp\u003eChapter 7. High-Throughput NMR Techniques for Combinatorial Chemical Library Analysis (T. Hou \u0026amp; D. Raftery).\u003c\/p\u003e \u003cp\u003eChapter 8. Micellar Electrokinetic Chromatography as a Tool for Combinatorial Chemistry Analysis: Theory and Applications (P. Simms).\u003c\/p\u003e \u003cp\u003eChapter 9. Characterization of Split-Pool Encoded Combinatorial Libraries (J. Zhang \u0026amp; W. Fitch).\u003c\/p\u003e \u003cp\u003ePART III: HIGH-THROUGHPUT PURIFICATION TO IMPROVE LIBRARY QUALITY.\u003c\/p\u003e \u003cp\u003eCha pter 10. Strategies and Methods for Purifying Organic Compounds and Combinatorial Libraries (J. Zhao, \u003ci\u003eet al\u003c\/i\u003e.).\u003c\/p\u003e \u003cp\u003eChapter 11. HTP of Combinatorial Chemistry Libraries (J. Hochlowski).\u003c\/p\u003e \u003cp\u003eChapter 12. Practical HPLC in High Throughput Analysis and Purification (H. Gumm \u0026amp; R. God).\u003c\/p\u003e \u003cp\u003ePART IV: ANALYSIS FOR COMPOUND STABILITY AND DRUGABILITY.\u003c\/p\u003e \u003cp\u003eChapter 13. Organic Compound Stability in Large, Diverse Phatmaceutical Screening Collection (K. Morand \u0026amp; X. Cheng).\u003c\/p\u003e \u003cp\u003eChapter 14. Quartz Crystal Microbalance in Biomolecular Recognition (M. Tseng, \u003ci\u003eet al\u003c\/i\u003e.).\u003c\/p\u003e \u003cp\u003eChapter 15. High-Throughput Physicochemical Profiling: Potential and Limitations (B. Faller).\u003c\/p\u003e \u003cp\u003eChapter 16. Solubility in the Design of Combinatorial Libraries (C. Lipinski).\u003c\/p\u003e \u003cp\u003eChapter 17. High-Throughput Determination of Log \u003ci\u003eD\u003c\/i\u003e Values by LC\/MS Method (J. Villena, \u003ci\u003eet al\u003c\/i\u003e.). \u003c\/p\u003e \u003cp\u003eIndex. \u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Chemistry [\u003ca title=\"See our other books on Chemistry\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Chemistry%20%5BPN%5D%22\"\u003ePN\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Wiley-Interscience","offers":[{"title":"Brand New","offer_id":52286377459992,"sku":"9780471269298","price":115.89,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/files\/9780471269298.jpg?v=1781550885","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/analysis-and-purification-methods-in-combinatorial-chemistry-hardback-9780471269298","provider":"Freshly Printed Books","version":"1.0","type":"link"}