{"product_id":"an-introduction-to-molecular-anthropology-paperback-softback-9781394262595","title":"An Introduction to Molecular Anthropology (Paperback \/ softback) 9781394262595","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eAn Introduction to Molecular Anthropology\u003c\/font\u003e\u003cbr\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003c\/p\u003e\n\u003cp\u003e\u003cfont size=\"4\"\u003eMark Stoneking (Author)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9781394262595, Wiley\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003ePaperback \/ softback, published 10 November 2025\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e464 pages\u003cbr\u003e26.9 x 21.3 x 2.5 cm, 1.225 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003e\u003cp\u003e\u003cb\u003eA freshly updated discussion of the foundations of—and latest developments in—molecular anthropology\u003c\/b\u003e \u003c\/p\u003e\n\u003cp\u003eIn the newly revised second edition of \u003ci\u003eAn Introduction to Molecular Anthropology,\u003c\/i\u003e retired researcher Dr. Mark Stoneking delivers an essential primer on genetics and molecular anthropology. The book is an accessible resource that covers key recent developments in the production and analysis of genome-wide data that highlights advances in methods and technologies, as well as the latest findings from ancient DNA. \u003c\/p\u003e\n\u003cp\u003eThe updated chapters build on basic genetics and evolutionary concepts to demonstrate how to make inferences about human population history and human evolution in the genomics age. It explores how evolution influences genes, how genes evolve, the different kinds of genetic variation in humans and how they are analyzed, and the latest technologies and ethical issues that arise from the sampling of modern populations. \u003c\/p\u003e\n\u003cp\u003eReaders will also find: \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eA thorough introduction to the genetic evidence of human origins and the spread of humans around the world\u003c\/li\u003e\n\u003cli\u003eComprehensive explorations of the role of selection and adaptation in human evolution\u003c\/li\u003e\n\u003cli\u003ePractical discussions of the impact of culture on human genetic variation\u003c\/li\u003e\n\u003cli\u003eComplete treatments of likely future developments within molecular anthropology in the genomics era\u003c\/li\u003e\n\u003c\/ul\u003e \u003cp\u003ePerfect for anthropology students and others studying introductory human evolution, \u003ci\u003eAn Introduction to Molecular Anthropology \u003c\/i\u003ewill also benefit practicing anthropologists and researchers in a variety of fields that touch on this topic.\u003c\/p\u003e\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e\u003cp\u003ePreface to the Second Edition xi\u003c\/p\u003e \u003cp\u003ePreface to the First Edition xiii\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 Genes: How They Are Inherited 1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eBlood and ABO Blood Groups 1\u003c\/p\u003e \u003cp\u003eInheritance of ABO Blood Groups 2\u003c\/p\u003e \u003cp\u003eInheritance of More than One Gene: ABO and Rhesus Blood Groups 4\u003c\/p\u003e \u003cp\u003eSex Chromosomes 8\u003c\/p\u003e \u003cp\u003eDetermining How Traits Are Inherited: Pedigree Analysis 9\u003c\/p\u003e \u003cp\u003eWhat Is – and Isn’t – Inherited 11\u003c\/p\u003e \u003cp\u003eConcluding Remarks 13\u003c\/p\u003e \u003cp\u003eReferences 13\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 What Genes Are, What They Do, and How They Do It 15\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eChromosomes, Proteins, and Nucleic Acids: Figuring Out What Genes Are 15\u003c\/p\u003e \u003cp\u003eThe Structure of Genes and What They Do: The Central Dogma and the Flow of Information 18\u003c\/p\u003e \u003cp\u003eHow Genes Do What They Do: Transcription and Translation 18\u003c\/p\u003e \u003cp\u003eThe Genetic Code 22\u003c\/p\u003e \u003cp\u003eDNA Replication 23\u003c\/p\u003e \u003cp\u003eThe Consequences of Mutations 23\u003c\/p\u003e \u003cp\u003eWhat Causes Mutations? 25\u003c\/p\u003e \u003cp\u003eA Final Cautionary Note 26\u003c\/p\u003e \u003cp\u003eReferences 26\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Genes in Populations 27\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eWhat Is a Population? 27\u003c\/p\u003e \u003cp\u003eThe Concept of “Effective Population Size” 28\u003c\/p\u003e \u003cp\u003eThe Sex Ratio and N e 29\u003c\/p\u003e \u003cp\u003eInbreeding and N e 30\u003c\/p\u003e \u003cp\u003eVariation in Population Size over Time and N e 31\u003c\/p\u003e \u003cp\u003eDifferential Fertility and N e 31\u003cbr\u003e \u003ci\u003eN e for Humans 33\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eThe Gene Pool with No Evolution: The Hardy–Weinberg Principle 34\u003c\/p\u003e \u003cp\u003eExceptions 37\u003c\/p\u003e \u003cp\u003eA Real-life Example 38\u003c\/p\u003e \u003cp\u003eSome Practical Uses for Hardy–Weinberg 41\u003c\/p\u003e \u003cp\u003eReferences 44\u003c\/p\u003e \u003cp\u003eftoc.indd 7 12-09-2025 19:08:06\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Evolutionary Forces 45\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eNonrandom Mating 46\u003c\/p\u003e \u003cp\u003eSmall Population Size 49\u003c\/p\u003e \u003cp\u003eMutation 54\u003c\/p\u003e \u003cp\u003eMigration 59\u003c\/p\u003e \u003cp\u003eSelection 63\u003c\/p\u003e \u003cp\u003eEvolutionary Forces: Summary 72\u003c\/p\u003e \u003cp\u003eReferences 73\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Molecular Evolution 75\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eFunctionally Less Important Molecules (or Parts of Molecules) Evolve Faster than More Important Ones 76\u003c\/p\u003e \u003cp\u003eConservative Substitutions Occur More Frequently than Disruptive Ones 77\u003c\/p\u003e \u003cp\u003eThe Rate of Molecular Evolution Is Approximately Constant 78\u003c\/p\u003e \u003cp\u003eContrasting Phenotypic and Molecular Evolution 79\u003c\/p\u003e \u003cp\u003eHow Do New Gene Functions Arise? 81\u003c\/p\u003e \u003cp\u003eGene Regulation and Phenotypic Evolution 83\u003c\/p\u003e \u003cp\u003eReferences 84\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 Genetic Markers 85\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eThe First DNA Markers: Restriction Fragment Length Polymorphisms 85\u003c\/p\u003e \u003cp\u003ePolymerase Chain Reaction 87\u003c\/p\u003e \u003cp\u003eDNA Sequencing: The Sanger Method 89\u003c\/p\u003e \u003cp\u003eNext-generation Sequencing 91\u003c\/p\u003e \u003cp\u003eTargeting Single DNA Bases: SNPS 93\u003c\/p\u003e \u003cp\u003eVariation in Length 95\u003c\/p\u003e \u003cp\u003eOther Structural Variation 101\u003c\/p\u003e \u003cp\u003eConcluding Remarks 102\u003c\/p\u003e \u003cp\u003eReferences 102\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 Ancient DNA 105\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eProperties of Ancient DNA: Degradation 105\u003c\/p\u003e \u003cp\u003eProperties of Ancient DNA: Damage 105\u003c\/p\u003e \u003cp\u003eProperties of Ancient DNA: Contamination 108\u003c\/p\u003e \u003cp\u003eHistory of Ancient DNA Studies 112\u003c\/p\u003e \u003cp\u003eReferences 114\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 Sampling Issues 115\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eSampling Populations: General Issues 115\u003c\/p\u003e \u003cp\u003eSampling Populations: Ethical Issues 117\u003c\/p\u003e \u003cp\u003eArchival Samples 121\u003c\/p\u003e \u003cp\u003eAncient Remains 122\u003c\/p\u003e \u003cp\u003eSampling DNA Regions 123\u003c\/p\u003e \u003cp\u003eMitochondrial DNA 124\u003c\/p\u003e \u003cp\u003eY Chromosomal DNA 131\u003c\/p\u003e \u003cp\u003eAutosomal DNA 132\u003c\/p\u003e \u003cp\u003eX Chromosome 134\u003c\/p\u003e \u003cp\u003ePublic Databases 135\u003c\/p\u003e \u003cp\u003eReferences 138\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 Analysis of Genetic Data from Populations 141\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eGenetic Diversity Within Populations 141\u003c\/p\u003e \u003cp\u003eGenetic Distances Between Populations 144\u003c\/p\u003e \u003cp\u003eAnalysis of Molecular Variance (AMOVA) and Mantel Tests 146\u003c\/p\u003e \u003cp\u003eDisplaying Genetic Distance Data: Trees 151\u003c\/p\u003e \u003cp\u003eDisplaying Genetic Data: Multidimensional Scaling, Principal Components, and Correspondence Analysis 156\u003c\/p\u003e \u003cp\u003eReferences 162\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 Analysis of Genetic Data from Individuals 163\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eGenetic Distances for DNA Sequences 163\u003c\/p\u003e \u003cp\u003eTrees for DNA Sequences 169\u003c\/p\u003e \u003cp\u003eRooting Trees 171\u003c\/p\u003e \u003cp\u003eAssessing the Confidence of a Tree 173\u003c\/p\u003e \u003cp\u003eNetwork Analyses 177\u003c\/p\u003e \u003cp\u003eGenome-wide Data: Unsupervised Analyses 179\u003c\/p\u003e \u003cp\u003eReferences 189\u003c\/p\u003e \u003cp\u003e\u003cb\u003e11 Inferences About Demographic History (Part 1) 191\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eDating Events 191\u003c\/p\u003e \u003cp\u003ePopulation Size and Population Size Change 206\u003c\/p\u003e \u003cp\u003eReferences 212\u003c\/p\u003e \u003cp\u003e\u003cb\u003e12 Inferences About Demographic History (Part 2) 213\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eMigration and Admixture 213\u003c\/p\u003e \u003cp\u003ePutting It All Together: Simulations 227\u003c\/p\u003e \u003cp\u003eReferences 230\u003c\/p\u003e \u003cp\u003e\u003cb\u003e13 Human Origins 233\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eOur Closest Living Relatives 233\u003c\/p\u003e \u003cp\u003eResolving the Trichotomy 236\u003c\/p\u003e \u003cp\u003eComplications 238\u003c\/p\u003e \u003cp\u003eApe Genetics and Genomics 240\u003c\/p\u003e \u003cp\u003eThe Origins of Our Species: Insights from Modern Populations 241\u003c\/p\u003e \u003cp\u003eThe Genetic Evidence: mtDNA 251\u003c\/p\u003e \u003cp\u003eThe Genetic Evidence: Y Chromosome 253\u003c\/p\u003e \u003cp\u003eThe Genetic Evidence: Autosomes 254\u003c\/p\u003e \u003cp\u003eReferences 257\u003c\/p\u003e \u003cp\u003e\u003cb\u003e14 The Origins of Our Species: Insights from Archaic Genomes 259\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eEnter the Denisovans 263\u003c\/p\u003e \u003cp\u003eThe Plot Thickens: Multiple Contributions of Ancestry from Archaic to Modern Humans… 270\u003c\/p\u003e \u003cp\u003e… And Multiple Contributions of Ancestry from Modern to Archaic Humans! 273\u003c\/p\u003e \u003cp\u003eSome Concluding Remarks 277\u003c\/p\u003e \u003cp\u003eReferences 279\u003c\/p\u003e \u003cp\u003e\u003cb\u003e15 Migration and Dispersal: The Colonization of the Americas 283\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eInto Remote Lands: The Colonization of the Americas 287\u003c\/p\u003e \u003cp\u003eReferences 300\u003c\/p\u003e \u003cp\u003e\u003cb\u003e16 Into Even More Remote Lands: The Colonization of Polynesia 303\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eWhat About Micronesia? 316\u003c\/p\u003e \u003cp\u003eContact Between Polynesia and the Americas? 319\u003c\/p\u003e \u003cp\u003eSome Concluding Remarks 322\u003c\/p\u003e \u003cp\u003eReferences 322\u003c\/p\u003e \u003cp\u003e\u003cb\u003e17 Species-wide Selection 325\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eSpecies-wide Selection 326\u003c\/p\u003e \u003cp\u003eNonsynonymous Substitutions and the dN\/dS Ratio 326\u003c\/p\u003e \u003cp\u003eTests Based on the Allele Frequency Distribution 331\u003c\/p\u003e \u003cp\u003eSelection Tests Based on Comparing Divergence to Polymorphism 336\u003c\/p\u003e \u003cp\u003eArchaic Genomes 339\u003c\/p\u003e \u003cp\u003eReferences 342\u003c\/p\u003e \u003cp\u003e\u003cb\u003e18 Local Selection 345\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eExample: Lactase Persistence 349\u003c\/p\u003e \u003cp\u003eExample: EDAR 355\u003c\/p\u003e \u003cp\u003eUsing Admixture to Detect Selection 365\u003c\/p\u003e \u003cp\u003eConcluding Remarks 369\u003c\/p\u003e \u003cp\u003eReferences 369\u003c\/p\u003e \u003cp\u003e\u003cb\u003e19 The Genetic Basis of Phenotypic Variation 373\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eSkin Pigmentation Variation 374\u003c\/p\u003e \u003cp\u003eHair and Eye Color Variation 381\u003c\/p\u003e \u003cp\u003eOther Traits 383\u003c\/p\u003e \u003cp\u003ePredicting Ancient Phenotypes 386\u003c\/p\u003e \u003cp\u003eReferences 387\u003c\/p\u003e \u003cp\u003e\u003cb\u003e20 Genes and Culture 389\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eAre Humans Still Evolving? 389\u003c\/p\u003e \u003cp\u003eGenetic Variation Can Be Directly Influenced by Cultural Practices 390\u003c\/p\u003e \u003cp\u003eGenetic Variation Can Be Indirectly Influenced by Cultural Practices 392\u003c\/p\u003e \u003cp\u003eUsing Genetic Analyses to Learn More About Cultural Practices: Farming\/Language Family Expansions 396\u003c\/p\u003e \u003cp\u003eUsing Genetic Analyses to Learn More About Cultural Practices: Dating the Origin of Clothing 403\u003c\/p\u003e \u003cp\u003eConcluding Remarks 407\u003c\/p\u003e \u003cp\u003eReferences 408\u003c\/p\u003e \u003cp\u003e\u003cb\u003e21 Ongoing and Future Developments in Molecular Anthropology 411\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eMore Modern and Ancient DNA Genomic Studies 411\u003c\/p\u003e \u003cp\u003eThe Other “OMICS” 414\u003c\/p\u003e \u003cp\u003eBeyond “YOU”: The Microbiome 419\u003c\/p\u003e \u003cp\u003eMore Analyses 427\u003c\/p\u003e \u003cp\u003eFiguring Out What Mutations Do: Functional Genomics 430\u003c\/p\u003e \u003cp\u003ePersonal Ancestry Testing and Genomics 431\u003c\/p\u003e \u003cp\u003eReferences 436\u003c\/p\u003e \u003cp\u003eIndex 439\u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Biology, life sciences [\u003ca title=\"See our other books on Biology, life sciences\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Biology,%20life%20sciences%20%5BPS%5D%22\"\u003ePS\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Wiley","offers":[{"title":"Brand New","offer_id":52433237967128,"sku":"9781394262595","price":83.78,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/files\/9781394262595.jpg?v=1784852639","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/an-introduction-to-molecular-anthropology-paperback-softback-9781394262595","provider":"Freshly Printed Books","version":"1.0","type":"link"}