{"product_id":"alpha-1-antitrypsin-deficiency-biology-diagnosis-clinical-significance-and-emerging-therapies-paperback-9780128039427","title":"Alpha-1-antitrypsin Deficiency; Biology, Diagnosis, Clinical Significance, and Emerging Therapies (Paperback) 9780128039427","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eAlpha-1-antitrypsin Deficiency\u003c\/font\u003e\u003cbr\u003e\r\n\u003cfont size=\"5\"\u003eBiology, Diagnosis, Clinical Significance, and Emerging Therapies\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cem\u003e\u003cp\u003eAuthoritative reference on research on the diagnosis, monitoring and treatment of AAT deficiency \u003c\/p\u003e\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eNoor Kalsheker (Author), Robert Andrew Stockley (Author)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780128039427, Elsevier Science\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003ePaperback, published 8 June 2017\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e262 pages\u003cbr\u003e22.9 x 15.1 x 1.7 cm, 0.43 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003e\u003cp\u003e\u003ci\u003eAlpha-1-antitrypsin Deficiency: Biology, Diagnosis, Clinical Significance, and Emerging Therapies\u003c\/i\u003e is the authoritative reference on AATD, providing standards for diagnosis, monitoring, treatment and appropriate avenues of research.\u003c\/p\u003e  \u003cp\u003eThe book covers the disease from basic biology and epidemiology, to clinical impact, and includes the understanding of the natural history of the disease and the significant advances that have been made in the last 20 years, including the three-dimensional structure of the molecule, its broad biological activity and improved therapeutic options, including replacement therapy and gene therapy. \u003c\/p\u003e  \u003cp\u003eThe editors have recruited international experts in the field to contribute evidence-based chapters and insights on future developments in the understanding of this disease.\u003c\/p\u003e\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e1. Historical perspective2. The Swedish AAT screening study: What we have learnt-from birth through to young middle age3. Gene regulation4. AAT variants5. AAT structure and function6. Novel biological functions of A1AT7. AATD and lung disease8. Alpha-1-Antitrypsin Deficiency Liver Disease9. AATD epidemiological studies and other AATD associated diseases10. THORACIC CT IMAGING IN AATD11. Animal models of alpha-1 antitrypsin deficiency12. Establishing European Registries for AATD and clinical trials for lung disease13. Establishing the USA Registry: logistics, impact and early clinical trials14. Gene therapy15. The future of AAT research\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Physiology [\u003ca title=\"See our other books on Physiology\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Physiology%20%5BMFG%5D%22\"\u003eMFG\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Academic Press","offers":[{"title":"Default Title","offer_id":46648997576984,"sku":"9780128039427","price":102.79,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/products\/9780128039427.jpg?v=1694095943","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/alpha-1-antitrypsin-deficiency-biology-diagnosis-clinical-significance-and-emerging-therapies-paperback-9780128039427","provider":"Freshly Printed Books","version":"1.0","type":"link"}