{"product_id":"advances-in-protein-chemistry-and-structural-biology-hardback-9780123812780","title":"Advances in Protein Chemistry and Structural Biology (Hardback) 9780123812780","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eAdvances in Protein Chemistry and Structural Biology\u003c\/font\u003e\u003cbr\u003e\r\n\r\n\r\n\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eThis volume presents step-by-step techniques for researchers that will predict the structure and potential function of proteins by identifying its coding sequence\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eAlexander McPherson (Author)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780123812780, Elsevier Science\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 9 September 2010\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e240 pages\u003cbr\u003e22.9 x 15.1 x 2.1 cm, 0.54 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003e\u003cp\u003eStructural genomics is the systematic determination of 3-D structures of proteins representative of the range of protein structure and function found in nature. The goal is to build a body of structural information that will predict the structure and potential function for almost any protein from knowledge of its coding sequence. This is essential information for understanding the functioning of the human proteome, the ensemble of tens of thousands of proteins specified by the human genome.\u003c\/p\u003e  \u003cp\u003eWhile most structural biologists pursue structures of individual proteins or protein groups, specialists in structural genomics pursue structures of proteins on a genome wide scale. This implies large-scale cloning, expression and purification. One main advantage of this approach is economy of scale.\u003c\/p\u003e\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e\u003cp\u003e1. Genomic studies and computational predictions of nucleosome positions and formation energies\u003ci\u003eAlexandre V. Morozov\u003csup\u003e \u003c\/sup\u003eand Denis Tolkunov \u003c\/i\u003e2. Protein Homorepeats : Sequences, Structures, Evolution and Functions\u003ci\u003eAndrey V. Kajava and Julien Jorda\u003c\/i\u003e3. Protein Aggregation: from Inclusion Bodies to Amyloid and Biomaterials \u003ci\u003eAnna Mitraki\u003c\/i\u003e4. Taking charge of proteins: from neurodegeneration to industrial biotechnology Bryan F. Shaw\u003csup\u003e \u003c\/sup\u003e, Demetri T. \u003ci\u003eMoustakas , Julian P. Whitelegge , and Kym F. Faull \u003c\/i\u003e5. Histone Acetylation, Acetyltransferases, and Ataxia - Alteration of Histone Acetylation and Chromatin Dynamics is Implicated in the Pathogenesis of Polyglutamine Expansion Disorders Jean-Pol Vigneron and Priscilla Simonis\u003ci\u003eShaun D. McCullough and Patrick Gran\u003c\/i\u003e\u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Cellular biology [\u003ca title=\"See our other books on Cellular biology\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Cellular%20biology%20%5Bcytology%5D%20%5BPSF%5D%22\"\u003ecytology PSF\u003c\/a\u003e], Molecular biology [\u003ca title=\"See our other books on Molecular biology\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Molecular%20biology%20%5BPSD%5D%22\"\u003ePSD\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Academic Press","offers":[{"title":"Default Title","offer_id":46649313427736,"sku":"9780123812780","price":88.35,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/products\/9780123812780.jpg?v=1695013996","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/advances-in-protein-chemistry-and-structural-biology-hardback-9780123812780","provider":"Freshly Printed Books","version":"1.0","type":"link"}