{"product_id":"a-practical-guide-to-the-histology-of-the-mouse-hardback-9781119941200","title":"A Practical Guide to the Histology of the Mouse (Hardback) 9781119941200","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eA Practical Guide to the Histology of the Mouse\u003c\/font\u003e\u003cbr\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003c\/p\u003e\n\u003cp\u003e\u003cfont size=\"4\"\u003eCheryl L. Scudamore (Author)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9781119941200, Wiley\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 14 February 2014\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e256 pages\u003cbr\u003e25.4 x 19.3 x 1.8 cm, 0.717 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cem\u003e\u003cfont size=\"3\"\u003e\u003cp\u003e\u003ci\u003e“\u003c\/i\u003eOverall this is a clearly written and well illustrated guide to the histology of the mouse, but also goes a step further by providing information on selected techniques, background pathology, potential artefacts and additional procedures associated with the examination of this commonly used laboratory species. It should prove a useful reference for any scientist examining mice as part of their work or research.”  (\u003ci\u003eBTS News\u003c\/i\u003e, 1 September 2014)\u003c\/p\u003e \u003cp\u003e“The hardcover earns a recommendation as a practical addition to a reference library through the text’s succinct coverage of a complex topic to illustrate the basic histopathology of the mouse.”  (\u003ci\u003eVeterinary Pathology\u003c\/i\u003e, 31 October 2014)\u003c\/p\u003e \u003cp\u003e \u003c\/p\u003e\u003c\/font\u003e\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003e\u003cb\u003eA Practical Guide to the Histology of the Mouse \u003c\/b\u003eprovides a full-colour atlas of mouse histology. Mouse models of disease are used extensively in biomedical research with many hundreds of new models being generated each year. Complete phenotypic analysis of all of these models can benefit from histologic review of the tissues. \u003cp\u003eThis book is aimed at veterinary and medical pathologists who are unfamiliar with mouse tissues and scientists who wish to evaluate their own mouse models. It provides practical guidance on the collection, sampling and analysis of mouse tissue samples in order to maximize the information that can be gained from these tissues. As well as illustrating the normal microscopic anatomy of the mouse, the book also describes and explains the common anatomic variations, artefacts associated with tissue collection and background lesions to help the scientist to distinguish these changes from experimentally- induced lesions.\u003c\/p\u003e \u003cp\u003eThis will be an essential bench-side companion for researchers and practitioners looking for an accessible and well-illustrated guide to mouse pathology.\u003c\/p\u003e \u003cul\u003e \u003cli\u003eWritten by experienced pathologists and specifically tailored to the needs of scientists and histologists\u003c\/li\u003e \u003cli\u003eFull colour throughout\u003c\/li\u003e \u003cli\u003eProvides advice on sampling tissues, necropsy and recording data\u003c\/li\u003e \u003cli\u003eIncludes common anatomic variations, background lesions and artefacts which will help non-experts understand whether histologic variations seen are part of the normal background or related to their experimental manipulation\u003c\/li\u003e \u003c\/ul\u003e\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e\u003cp\u003eList of contributors ix\u003c\/p\u003e \u003cp\u003eForeword xi\u003c\/p\u003e \u003cp\u003ePreface xiii\u003c\/p\u003e \u003cp\u003eAbout the companion website xv\u003c\/p\u003e \u003cp\u003e\u003cb\u003eChapter 1 Necropsy of the mouse 1\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eLorna Rasmussen and Elizabeth McInnes\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e1.1 Recording of findings 2\u003c\/p\u003e \u003cp\u003e1.2 Bleeding technique 3\u003c\/p\u003e \u003cp\u003e1.3 Perfusion 3\u003c\/p\u003e \u003cp\u003e1.4 External examination 4\u003c\/p\u003e \u003cp\u003e1.5 Weighing of organs 6\u003c\/p\u003e \u003cp\u003e1.6 Positioning of mouse for necropsy and removing the skin 6\u003c\/p\u003e \u003cp\u003e1.7 Opening the abdominal cavity and exposing organs 9\u003c\/p\u003e \u003cp\u003e1.8 Removing the ribcage to expose lungs and heart 17\u003c\/p\u003e \u003cp\u003e1.9 Removing the brain and spinal cord 20\u003c\/p\u003e \u003cp\u003e1.10 Collecting and fixing tissue samples 22\u003c\/p\u003e \u003cp\u003eReferences 22\u003c\/p\u003e \u003cp\u003e\u003cb\u003eChapter 2 Practical approaches to reviewing and recording pathology data 25\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eCheryl L. Scudamore\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2.1 Sample selection and trimming patterns 26\u003c\/p\u003e \u003cp\u003e2.2 Controls 28\u003c\/p\u003e \u003cp\u003e2.3 Standardizing terminology 28\u003c\/p\u003e \u003cp\u003e2.4 Microscopic terminology 30\u003c\/p\u003e \u003cp\u003e2.5 Recording pathology data 33\u003c\/p\u003e \u003cp\u003e2.6 Quantitative versus semiquantitative analysis 35\u003c\/p\u003e \u003cp\u003e2.7 Semiquantitative techniques 37\u003c\/p\u003e \u003cp\u003e2.8 Quantitative techniques 38\u003c\/p\u003e \u003cp\u003eReferences 40\u003c\/p\u003e \u003cp\u003e\u003cb\u003eChapter 3 Gastrointestinal system 43\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eCheryl L. Scudamore\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3.1 Background and development 43\u003c\/p\u003e \u003cp\u003e3.2 Oral cavity 43\u003c\/p\u003e \u003cp\u003e3.3 Salivary glands 46\u003c\/p\u003e \u003cp\u003e3.4 Stomach and intestines 48\u003c\/p\u003e \u003cp\u003e3.5 Liver 56\u003c\/p\u003e \u003cp\u003e3.6 Pancreas 59\u003c\/p\u003e \u003cp\u003eReferences 61\u003c\/p\u003e \u003cp\u003e\u003cb\u003eChapter 4 Cardiovascular system 63\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eCheryl L. Scudamore\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4.1 Background and development 63\u003c\/p\u003e \u003cp\u003e4.2 Sampling techniques and morphometry 63\u003c\/p\u003e \u003cp\u003e4.3 Artefacts 65\u003c\/p\u003e \u003cp\u003e4.4 Anatomy and histology of the heart 67\u003c\/p\u003e \u003cp\u003e4.5 Anatomy and histology of the blood vessels 69\u003c\/p\u003e \u003cp\u003eReferences 72\u003c\/p\u003e \u003cp\u003e\u003cb\u003eChapter 5 Urinary system 75\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eElizabeth McInnes\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5.1 Background and development 75\u003c\/p\u003e \u003cp\u003e5.2 Sampling techniques 76\u003c\/p\u003e \u003cp\u003e5.3 Artefacts 76\u003c\/p\u003e \u003cp\u003e5.4 Background lesions 77\u003c\/p\u003e \u003cp\u003e5.5 Anatomy and histology 79\u003c\/p\u003e \u003cp\u003eReferences 85\u003c\/p\u003e \u003cp\u003e\u003cb\u003eChapter 6 Reproductive system 87\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eCheryl L. Scudamore\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6.1 Background and development of the male and female reproductive tract 87\u003c\/p\u003e \u003cp\u003e6.2 Female reproductive tract 88\u003c\/p\u003e \u003cp\u003e6.3 Male reproductive tract 97\u003c\/p\u003e \u003cp\u003eReferences 105\u003c\/p\u003e \u003cp\u003e\u003cb\u003eChapter 7 Endocrine system 109\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eIan Taylor\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7.1 Introduction 109\u003c\/p\u003e \u003cp\u003e7.2 Adrenals 109\u003c\/p\u003e \u003cp\u003e7.3 Pituitary 114\u003c\/p\u003e \u003cp\u003e7.4 Thyroids and parathyroids 117\u003c\/p\u003e \u003cp\u003eReferences 121\u003c\/p\u003e \u003cp\u003e\u003cb\u003eChapter 8 Nervous system 123\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eAude Roulois\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8.1 Introduction 123\u003c\/p\u003e \u003cp\u003e8.2 Necropsy 123\u003c\/p\u003e \u003cp\u003e8.3 Fixation\/perfusion 126\u003c\/p\u003e \u003cp\u003e8.4 Trimming 131\u003c\/p\u003e \u003cp\u003e8.5 Special stains and techniques 133\u003c\/p\u003e \u003cp\u003e8.6 Microscopic examination 137\u003c\/p\u003e \u003cp\u003e8.7 Normal histology-juvenile – CNS and PNS 137\u003c\/p\u003e \u003cp\u003e8.8 Artefacts – CNS and PNS 141\u003c\/p\u003e \u003cp\u003e8.9 Pathological changes and background pathology – CNS and PNS 142\u003c\/p\u003e \u003cp\u003e8.10 Acknowledgment 146\u003c\/p\u003e \u003cp\u003eReferences 146\u003c\/p\u003e \u003cp\u003eUseful website resources 148\u003c\/p\u003e \u003cp\u003e\u003cb\u003eChapter 9 Lymphoid and haematopoietic system 149\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eIan Taylor\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9.1 Introduction 149\u003c\/p\u003e \u003cp\u003e9.2 Lymph nodes 150\u003c\/p\u003e \u003cp\u003e9.3 Spleen 156\u003c\/p\u003e \u003cp\u003e9.4 MALT (mucosa-associated lymphoid tissue) 160\u003c\/p\u003e \u003cp\u003e9.5 Thymus 161\u003c\/p\u003e \u003cp\u003e9.6 Bone marrow 164\u003c\/p\u003e \u003cp\u003eReferences 166\u003c\/p\u003e \u003cp\u003e\u003cb\u003eChapter 10 Integument and adipose tissue 169\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eCheryl L. Scudamore\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10.1 Background and development 169\u003c\/p\u003e \u003cp\u003e10.2 Sampling technique 170\u003c\/p\u003e \u003cp\u003e10.3 Anatomy and histology 171\u003c\/p\u003e \u003cp\u003eReferences 177\u003c\/p\u003e \u003cp\u003e\u003cb\u003eChapter 11 The respiratory system 179\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eElizabeth McInnes\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e11.1 Background and development 179\u003c\/p\u003e \u003cp\u003e11.2 Embryology 179\u003c\/p\u003e \u003cp\u003e11.3 Anatomy and histology of the respiratory system 180\u003c\/p\u003e \u003cp\u003e11.4 Upper respiratory tract 180\u003c\/p\u003e \u003cp\u003e11.5 Lower respiratory tract 189\u003c\/p\u003e \u003cp\u003eReferences 193\u003c\/p\u003e \u003cp\u003e\u003cb\u003eChapter 12 Special senses 195\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eCheryl L. Scudamore\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e12.1 Background and development 195\u003c\/p\u003e \u003cp\u003e12.2 Sampling technique for the eye 195\u003c\/p\u003e \u003cp\u003e12.3 Artefacts 197\u003c\/p\u003e \u003cp\u003e12.4 Anatomy and histology of the eye and associated glands 199\u003c\/p\u003e \u003cp\u003e12.5 Background and development of the ear 204\u003c\/p\u003e \u003cp\u003e12.6 Sampling technique for the ear and associated structures 205\u003c\/p\u003e \u003cp\u003e12.7 Anatomy and histology of the ear and associated glands 206\u003c\/p\u003e \u003cp\u003eReferences 209\u003c\/p\u003e \u003cp\u003e\u003cb\u003eChapter 13 Musculoskeletal system 211\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eCheryl L. Scudamore\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e13.1 Background and development 211\u003c\/p\u003e \u003cp\u003e13.2 Sampling techniques 211\u003c\/p\u003e \u003cp\u003e13.3 Anatomy and histology 212\u003c\/p\u003e \u003cp\u003eReferences 218\u003cbr\u003e Index 221\u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Biology, life sciences [\u003ca title=\"See our other books on Biology, life sciences\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Biology,%20life%20sciences%20%5BPS%5D%22\"\u003ePS\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Wiley-Blackwell","offers":[{"title":"Brand New","offer_id":52165308088600,"sku":"9781119941200","price":88.47,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/files\/9781119941200.jpg?v=1781098175","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/a-practical-guide-to-the-histology-of-the-mouse-hardback-9781119941200","provider":"Freshly Printed Books","version":"1.0","type":"link"}