{"product_id":"a-pharmacology-primer-techniques-for-more-effective-and-strategic-drug-discovery-paperback-9780323992893","title":"A Pharmacology Primer; Techniques for More Effective and Strategic Drug Discovery (Paperback \/ softback) 9780323992893","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eA Pharmacology Primer\u003c\/font\u003e\u003cbr\u003e\r\n\u003cfont size=\"5\"\u003eTechniques for More Effective and Strategic Drug Discovery\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cem\u003eProvides in-depth discussion on advances in structure-based drug design, data-driven drug discovery and screening technologies\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eTerry P. Kenakin (Author)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780323992893, Elsevier Science\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003ePaperback \/ softback, published 23 August 2022\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e502 pages\u003cbr\u003e27.6 x 21.6 x 3.1 cm, 0.45 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003e\u003cp\u003e\u003ci\u003eA Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery, Sixth Edition\u003c\/i\u003e features the latest research surrounding the application of pharmacology in drug discovery in an effort to equip readers with a deeper understanding of complex and rapid changes in this field. Written by well-respected pharmacologist, Terry P. Kenakin, this primer is an indispensable resource for anyone involved in drug discovery. This edition has been reorganized for better flow and clarity and includes material on new technologies for screening (virtual, DNA encoded libraires, fragment-based) and a major section on phenotypic (target agnostic) screening for new leads and determination of drug targets. \u003c\/p\u003e  \u003cp\u003eWith full color illustrations as well as new examples throughout, this book remains a top reference for all industry and academic scientists and students directly involved in drug discovery or pharmacologic research. New material includes a discussion of the determination of target engagement, including numerous new ways to demonstrate the physical interaction of molecules with drug targets and new drug candidates such a mRNA, gene therapy, antibodies and information on CRISPR and genomics. \u003c\/p\u003e\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e1. What is Pharmacology?\u003cbr\u003e2. How Different Tissues Process Drug Response\u003cbr\u003e3. Drug–Receptor Theory\u003cbr\u003e4. Pharmacological Assay Formats: Binding\u003cbr\u003e5. Drug Targets and Drug-Target Molecules\u003cbr\u003e6. Agonists: The Measurement of Affinity and Efficacy in Functional Assays\u003cbr\u003e7. Orthosteric Drug Antagonism\u003cbr\u003e8. Allosteric Modulation\u003cbr\u003e9. The Optimal Design of Pharmacological Experiments\u003cbr\u003e10. Pharmacokinetics\u003cbr\u003e11. Safety Pharmacology\u003cbr\u003e12. The Drug Discovery Process\u003cbr\u003e13. Selected Pharmacological Methods\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Pharmacology [\u003ca title=\"See our other books on Pharmacology\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Pharmacology%20%5BMMG%5D%22\"\u003eMMG\u003c\/a\u003e], Pharmaceutical industries [\u003ca title=\"See our other books on Pharmaceutical industries\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Pharmaceutical%20industries%20%5BKNDP%5D%22\"\u003eKNDP\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Academic Press","offers":[{"title":"Default Title","offer_id":46648666784024,"sku":"9780323992893","price":88.45,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/products\/9780323992893_f083a8ea-6df6-43cf-8db1-62a451469305.jpg?v=1694976345","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/a-pharmacology-primer-techniques-for-more-effective-and-strategic-drug-discovery-paperback-9780323992893","provider":"Freshly Printed Books","version":"1.0","type":"link"}